{"id":"alminoprofen","rwe":[],"tags":[{"label":"alminoprofen","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"M01AE16","category":"atc"},{"label":"Active","category":"status"},{"label":"Analgesics","category":"pharmacology"},{"label":"Analgesics, Non-Narcotic","category":"pharmacology"},{"label":"Anti-Inflammatory Agents","category":"pharmacology"},{"label":"Anti-Inflammatory Agents, Non-Steroidal","category":"pharmacology"},{"label":"Antirheumatic Agents","category":"pharmacology"},{"label":"Peripheral Nervous System Agents","category":"pharmacology"},{"label":"Sensory System Agents","category":"pharmacology"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"minalfene","offLabel":[],"synonyms":["alminoprofen","(+/-)-Alminoprofen","minalfene"],"timeline":[],"brandName":"Minalfene","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"alminoprofen","explanation":"Think of inflammation like a fire in your body. Minalfene helps put out the fire by blocking the chemicals that make it burn. This can help reduce pain and swelling.","oneSentence":"Minalfene works by inhibiting enzymes involved in inflammation.","technicalDetail":"Minalfene is a small molecule inhibitor of certain enzymes, such as COX-2, which play a key role in the inflammatory response."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/126","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ALMINOPROFEN","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:37:48.232650","biosimilars":[],"competitors":[{"drugName":"ibuprofen","drugSlug":"ibuprofen","fdaApproval":"1974-09-19","patentExpiry":"Sep 30, 2029","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"naproxen","drugSlug":"naproxen","fdaApproval":"1976-03-11","genericCount":31,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"ketoprofen","drugSlug":"ketoprofen","fdaApproval":"1986-01-09","genericCount":7,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"fenoprofen","drugSlug":"fenoprofen","fdaApproval":"1976-03-16","genericCount":16,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"benoxaprofen","drugSlug":"benoxaprofen","fdaApproval":"1982-04-19","relationship":"same-class"},{"drugName":"suprofen","drugSlug":"suprofen","fdaApproval":"1988-12-23","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"flurbiprofen","drugSlug":"flurbiprofen","fdaApproval":"1986-12-31","genericCount":8,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"oxaprozin","drugSlug":"oxaprozin","fdaApproval":"1992-10-29","genericCount":13,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"esomeprazole","drugSlug":"esomeprazole","fdaApproval":"2001-02-20","patentExpiry":"Dec 8, 2036","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"misoprostol","drugSlug":"misoprostol","fdaApproval":"1988-12-27","genericCount":4,"patentStatus":"Off-patent — generic available","relationship":"same-class"}],"genericName":"alminoprofen","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"ibuprofen","brandName":"ibuprofen","genericName":"ibuprofen","approvalYear":"1974","relationship":"same-class"},{"drugId":"naproxen","brandName":"naproxen","genericName":"naproxen","approvalYear":"1976","relationship":"same-class"},{"drugId":"ketoprofen","brandName":"ketoprofen","genericName":"ketoprofen","approvalYear":"1986","relationship":"same-class"},{"drugId":"fenoprofen","brandName":"fenoprofen","genericName":"fenoprofen","approvalYear":"1976","relationship":"same-class"},{"drugId":"benoxaprofen","brandName":"benoxaprofen","genericName":"benoxaprofen","approvalYear":"1982","relationship":"same-class"},{"drugId":"suprofen","brandName":"suprofen","genericName":"suprofen","approvalYear":"1988","relationship":"same-class"},{"drugId":"flurbiprofen","brandName":"flurbiprofen","genericName":"flurbiprofen","approvalYear":"1986","relationship":"same-class"},{"drugId":"oxaprozin","brandName":"oxaprozin","genericName":"oxaprozin","approvalYear":"1992","relationship":"same-class"},{"drugId":"esomeprazole","brandName":"esomeprazole","genericName":"esomeprazole","approvalYear":"2001","relationship":"same-class"},{"drugId":"misoprostol","brandName":"misoprostol","genericName":"misoprostol","approvalYear":"1988","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"005223","UNII":"0255AHR9GJ","CHEBI":"CHEBI:31190","INN_ID":"4570","RXNORM":"17387","UMLSCUI":"C0051247","ChEMBL_ID":"CHEMBL1765293","KEGG_DRUG":"D01513","DRUGBANK_ID":"DB13314","PUBCHEM_CID":"2097","SNOMEDCT_US":"713469005","MESH_SUPPLEMENTAL_RECORD_UI":"C027953"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":21,"therapeuticAreas":["Pain"],"atcClassification":{"source":"DrugCentral","atcCode":"M01AE16","allCodes":["M01AE16"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Minalfene, also known as Alminoprofen, is a small molecule drug in the alminoprofen class. Its exact target and mechanism of action are unknown, but it is believed to work by inhibiting certain enzymes involved in inflammation. Minalfene is not FDA-approved for any indications, and its commercial status, including patent and generic availability, is unclear. Further research is needed to determine its safety and efficacy. As a result, key safety considerations and approved indications are currently unavailable.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}