{"id":"allert-low-dose","safety":{"commonSideEffects":[{"rate":null,"effect":"Local injection site reactions"},{"rate":null,"effect":"Systemic allergic reactions"},{"rate":null,"effect":"Pruritus"}]},"_chembl":{"chemblId":"CHEMBL2108580","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"AllerT works by presenting allergens in a form that promotes regulatory T cell (Treg) development and immune tolerance rather than allergic sensitization. The low-dose formulation is intended to shift the immune response from Th2-mediated allergic inflammation toward Th1/Treg-mediated tolerance, reducing allergic symptoms and potentially providing long-term desensitization.","oneSentence":"AllerT is an allergen immunotherapy designed to induce immune tolerance to allergens through low-dose, modified allergen exposure.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T03:21:08.433Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Allergic rhinitis and/or allergic asthma (in development)"}]},"trialDetails":[{"nctId":"NCT01720251","phase":"PHASE2","title":"Efficacy Study of a Preseasonal Treatment With AllerT in Subjects With Birch Pollen Allergy","status":"COMPLETED","sponsor":"Anergis","startDate":"2012-10","conditions":"Allergic Rhinitis, Rhinoconjunctivitis","enrollment":240}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["AllerT 25-50 micrograms"],"phase":"phase_2","status":"active","brandName":"AllerT low dose","genericName":"AllerT low dose","companyName":"Anergis","companyId":"anergis","modality":"Small molecule","firstApprovalDate":"","aiSummary":"AllerT is an allergen immunotherapy designed to induce immune tolerance to allergens through low-dose, modified allergen exposure. Used for Allergic rhinitis and/or allergic asthma (in development).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}