{"id":"allergen-immunotherapy","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Local reactions at injection site"},{"rate":"0.1-1%","effect":"Systemic reactions (e.g. anaphylaxis)"}]},"_chembl":{"chemblId":"CHEMBL2108717","moleculeType":"Cell"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This is achieved through subcutaneous injections or sublingual tablets that contain small amounts of the allergen, allowing the body to develop a protective immune response and reduce inflammation.","oneSentence":"Allergen immunotherapy works by gradually increasing exposure to specific allergens to build tolerance and reduce symptoms.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:21:08.065Z","_scrapedBy":"cloudflare-swarm","_wikipedia":{"url":"https://en.wikipedia.org/wiki/Allergen_immunotherapy","title":"Allergen immunotherapy","extract":"Allergen immunotherapy, also known as desensitization or hypo-sensitization, is a medical treatment for environmental allergies and asthma. Immunotherapy involves exposing people to increasing amounts of allergens in an attempt to change the immune system's response."},"indications":{"approved":[{"name":"Treatment of allergic rhinitis and asthma"}]},"trialDetails":[{"nctId":"NCT07419230","phase":"NA","title":"Evaluation of a Digital Tool to Improve Aeroallergen Immunotherapy Adherence. NavigAITme Project","status":"RECRUITING","sponsor":"Fundación de Investigación Biomédica - Hospital Universitario de La Princesa","startDate":"2026-03-11","conditions":"Allergic Rhinitis","enrollment":880},{"nctId":"NCT07412990","phase":"","title":"GRASS (Grass MATA MPL Real-world Assessment Study)","status":"RECRUITING","sponsor":"Allergy Therapeutics","startDate":"2026-03-11","conditions":"Grass Pollen Allergy","enrollment":1000},{"nctId":"NCT06960382","phase":"PHASE1, PHASE2","title":"Safety and Immunogenicity of Cat-allergen Intralymphatic Immunotherapy in Patients With Cat Allergy With and Without Asthma","status":"RECRUITING","sponsor":"University of Zurich","startDate":"2025-08-20","conditions":"Allergic Rhinitis, Allergic Asthma","enrollment":36},{"nctId":"NCT07447869","phase":"EARLY_PHASE1","title":"LYmph Node eXamination in Cat Allergen Immunotherapy","status":"NOT_YET_RECRUITING","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2026-03-19","conditions":"Allergy","enrollment":16},{"nctId":"NCT07452380","phase":"","title":"The Efficacy of Specific Immunotherapy Guided by Component-Resolved Diagnosis for Dust Mite Allergens in Chinese Pediatric Patients With Rhinitis and/or Asthma","status":"RECRUITING","sponsor":"The Children's Hospital of Zhejiang University School of Medicine","startDate":"2025-11-01","conditions":"Allergic Rhinitis Due to House Dust Mite","enrollment":1000},{"nctId":"NCT06378255","phase":"NA","title":"Clinical Evaluation of Polycation-based New Dental Desensitizer on Dentin Hypersensitivity","status":"COMPLETED","sponsor":"Peking University Hospital of Stomatology","startDate":"2024-03-20","conditions":"Dentin Sensitivity","enrollment":40},{"nctId":"NCT05460520","phase":"NA","title":"DevRobust Treatment for Mal de Débarquement Syndrome","status":"RECRUITING","sponsor":"Icahn School of Medicine at Mount Sinai","startDate":"2023-01-01","conditions":"Mal de Débarquement Syndrome","enrollment":200},{"nctId":"NCT06256146","phase":"NA","title":"Investigating Modified Protocols of Oral Immunotherapy to Validate Efficacy and Safety","status":"RECRUITING","sponsor":"McGill University Health Centre/Research Institute of the McGill University Health Centre","startDate":"2022-03-01","conditions":"Peanut Allergy, Milk Allergy, Cow's, Egg Allergy","enrollment":360},{"nctId":"NCT07348302","phase":"PHASE3","title":"Efficacy and Safety of SLIT in Patients With Rhinitis/RC With/Without Mild-moderate Asthma, Due to Dpt and/or Df","status":"RECRUITING","sponsor":"Inmunotek S.L.","startDate":"2025-04-02","conditions":"Rhinitis, Rhinoconjunctivitis","enrollment":736},{"nctId":"NCT07317960","phase":"PHASE1","title":"Phase I Study of PollenVax in Patients With Mugwort Pollen-Induced Allergic Rhinitis","status":"ACTIVE_NOT_RECRUITING","sponsor":"Kazakh National Agrarian University","startDate":"2025-11-22","conditions":"Allergic Rhinitis Due to Artemisia Pollen","enrollment":30},{"nctId":"NCT04259359","phase":"","title":"Predominant Sensitizations to Single Bee Venom Allergens as a Risk Factor for Therapy Failure","status":"RECRUITING","sponsor":"Medical University of Graz","startDate":"2019-05-02","conditions":"Bee Venom Allergy","enrollment":266},{"nctId":"NCT07269509","phase":"NA","title":"Evaluation of the Efficacy and Safety of an Intensified Strategy of Intratonsillar Immunotherapy (ITIT) for Allergic Rhinitis: A Multicenter, Randomized, Double-blind, Controlled Trial","status":"NOT_YET_RECRUITING","sponsor":"Renmin Hospital of Wuhan University","startDate":"2025-12-30","conditions":"Allergic Rhinitis","enrollment":276},{"nctId":"NCT06876506","phase":"","title":"Identification of B Regulatory Cells by Flow Cytometry","status":"NOT_YET_RECRUITING","sponsor":"Hull University Teaching Hospitals NHS Trust","startDate":"2026-02-01","conditions":"Pollen Allergy, Venom Allergy","enrollment":80},{"nctId":"NCT05714514","phase":"","title":"Survival and Dialysis Independency in Highly Sensitized Patients After Desensitization With Imlifidase and Tx of Kidneys","status":"ACTIVE_NOT_RECRUITING","sponsor":"Hansa Biopharma AB","startDate":"2023-04-21","conditions":"Kidney Transplantation in Highly Sensitized Patients","enrollment":64},{"nctId":"NCT06834165","phase":"PHASE4","title":"Study Evaluating the Safety and Efficacy of Neffy or Intramuscular Adrenalin in Patients With Allergic Reactions After Oral Food Challenge or Allergen Immunotherapy","status":"RECRUITING","sponsor":"ARS Pharmaceuticals, Inc.","startDate":"2025-05-20","conditions":"Allergic Reactions","enrollment":600},{"nctId":"NCT05621317","phase":"PHASE2","title":"A Safety and Efficacy Study of PVX108 in Children and Adolescents With Peanut Allergy","status":"ACTIVE_NOT_RECRUITING","sponsor":"Aravax Pty Ltd","startDate":"2023-02-09","conditions":"Peanut Allergy, Peanut Hypersensitivity, Peanut-Induced Anaphylaxis","enrollment":90},{"nctId":"NCT07197437","phase":"NA","title":"Efficacy of Universal Bonding Agents as Desensitizers","status":"COMPLETED","sponsor":"Peking University Hospital of Stomatology","startDate":"2023-02-27","conditions":"Dentin Hypersensitivity","enrollment":14},{"nctId":"NCT06085963","phase":"NA","title":"Nasal Allergen Challenge Test as a Method to Detect Clinical Reactivity Against Birch Pollen","status":"COMPLETED","sponsor":"Karolinska Institutet","startDate":"2023-02-01","conditions":"Allergic Rhinitis Due to Pollen","enrollment":89},{"nctId":"NCT07171307","phase":"","title":"Treg Effector Function and Th2/Treg Ratio in Allergic Conjunctivitis: Effect of Desensitization Therapy","status":"NOT_YET_RECRUITING","sponsor":"Instituto de Oftalmología Fundación Conde de Valenciana","startDate":"2026-01-01","conditions":"Conjunctivitis, Allergic","enrollment":60},{"nctId":"NCT05738798","phase":"NA","title":"Oral Immunotherapy in Young Children With Food Allergy","status":"ENROLLING_BY_INVITATION","sponsor":"Deventer Ziekenhuis","startDate":"2023-02-01","conditions":"Food Allergy","enrollment":500},{"nctId":"NCT06533462","phase":"NA","title":"Randomized Controlled Trial of Slow Multiallergen Oral Immunotherapy in Young Children","status":"RECRUITING","sponsor":"Karolinska Institutet","startDate":"2024-11-08","conditions":"Food Allergy, Oral Immunotherapy for Food Allergy","enrollment":80},{"nctId":"NCT03881696","phase":"PHASE3","title":"Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic Participants","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2019-07-22","conditions":"Peanut Allergy, Multi-food Allergy","enrollment":471},{"nctId":"NCT07158619","phase":"NA","title":"Sustained Unresponsiveness (SU) to Cashew Nut Protein Following Oral Allergen-Specific Immunotherapy","status":"NOT_YET_RECRUITING","sponsor":"Medical University of Warsaw","startDate":"2025-09","conditions":"Food Allergy in Children","enrollment":39},{"nctId":"NCT07149298","phase":"","title":"Quality of Life In Patients With Allergic Conjunctivitis In Treatment With Sublingual Allergen Immunotherapy In A Referral Ophthalmological Hospital","status":"ACTIVE_NOT_RECRUITING","sponsor":"Instituto de Oftalmología Fundación Conde de Valenciana","startDate":"2014-03-24","conditions":"Allergic Conjunctivitis of Both Eyes","enrollment":100},{"nctId":"NCT06448585","phase":"PHASE4","title":"Dietary Supplement (Beta-Glucans) in Allergic Patients Undergoing Subcutaneous Immunotherapy.","status":"COMPLETED","sponsor":"Gala Servicios Clinicos S.L.","startDate":"2024-05-29","conditions":"Rhinitis, Allergic Rhinoconjunctivitis, Rhinoconjunctivitis","enrollment":60},{"nctId":"NCT05191186","phase":"PHASE3","title":"Documentation of Efficacy of Intralymphatic Allergen Immunotherapy","status":"COMPLETED","sponsor":"Aarhus University Hospital","startDate":"2020-02-01","conditions":"Allergic Rhinitis Due to Grass Pollen, Allergic Conjunctivitis of Both Eyes, Allergic Asthma","enrollment":450},{"nctId":"NCT07073404","phase":"","title":"Omalizumab for Plant-Food Allergy Due to Sensitization to LTP or Profilin","status":"NOT_YET_RECRUITING","sponsor":"Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud","startDate":"2026-01","conditions":"Food Allergies","enrollment":37},{"nctId":"NCT07107451","phase":"NA","title":"Sustained Unresponsiveness (SU) to Sesame Protein Following Low-dose Oral Allergen-specific Immunotherapy","status":"NOT_YET_RECRUITING","sponsor":"Medical University of Warsaw","startDate":"2025-08","conditions":"Food Allergy in Children","enrollment":39},{"nctId":"NCT07096440","phase":"","title":"Noninterventional Study on Tolerability and Safety of One Strength Updosing With Novo-Helisen Depot House Dust Mites","status":"NOT_YET_RECRUITING","sponsor":"Allergopharma GmbH & Co. KG","startDate":"2025-07-30","conditions":"Allergic Rhinitis Due to House Dust Mite, Allergic Conjunctivitis Due to Dermatophagoides Farinae, Allergic Conjunctivitis Due to Dermatophagoides Pteronyssinus","enrollment":105},{"nctId":"NCT04502966","phase":"PHASE2","title":"Grass Pollen Immunotherapy Plus Dupilumab for Tolerance Induction","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2020-11-09","conditions":"Allergic Rhinoconjunctivitis, Grass Pollen Allergy","enrollment":108},{"nctId":"NCT06421415","phase":"","title":"Long Term Effect of AIT in Children","status":"RECRUITING","sponsor":"Odense University Hospital","startDate":"2024-05-01","conditions":"Allergy in Children","enrollment":100},{"nctId":"NCT05503446","phase":"NA","title":"Using Commonly Available Food Products To Treat Food Allergy","status":"RECRUITING","sponsor":"University of Southampton","startDate":"2023-01-19","conditions":"IgE-Mediated Cow Milk Allergy, Peanut Allergy","enrollment":216},{"nctId":"NCT05560698","phase":"NA","title":"A Motivation-enhancing App to Retain Patients With Hay Fever in a Trial After Treatment","status":"COMPLETED","sponsor":"University of Aarhus","startDate":"2022-09-26","conditions":"Grass Pollen Allergy, Rhinoconjunctivitis","enrollment":224},{"nctId":"NCT07013123","phase":"PHASE3","title":"Potency of HDM Sublingual AIT Tablets in Assuring the Persistency of Asthma Control in HDM Allergic Patients With Severe Asthma, Treated With Tezepelumab","status":"NOT_YET_RECRUITING","sponsor":"University Hospital, Montpellier","startDate":"2025-07-15","conditions":"Severe Asthma, Allergy to House Dust Mites","enrollment":38},{"nctId":"NCT06997432","phase":"","title":"Endophenotyping for Plant-based Food Allergy Diagnosis, Tolerance Biomarkers, and Mechanisms in Microneedle Immunotherapy","status":"NOT_YET_RECRUITING","sponsor":"Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud","startDate":"2025-06","conditions":"Food Allergies","enrollment":32},{"nctId":"NCT05960266","phase":"EARLY_PHASE1","title":"Immunological Analysis of Lymph Node Tissue After Intralymphatic Immunotherapy: A Prospective Case Control Study","status":"COMPLETED","sponsor":"University of Zurich","startDate":"2023-11-23","conditions":"Hypersensitivity, Hay Fever, Rhinitis, Allergic, Seasonal","enrollment":28},{"nctId":"NCT03799328","phase":"PHASE2","title":"Low Dose Multi-OIT for Food Allergy (LoMo)","status":"COMPLETED","sponsor":"The Hospital for Sick Children","startDate":"2019-05-23","conditions":"Food Allergy","enrollment":18},{"nctId":"NCT05297760","phase":"PHASE1, PHASE2","title":"Intralymphatic Immunotherapy With Polvac Grass & Rye Allergen Extract","status":"COMPLETED","sponsor":"University of Zurich","startDate":"2022-02-10","conditions":"Rhinitis, Allergic, Seasonal, Rhinitis; Allergic, With Asthma, Allergic Rhinitis","enrollment":60},{"nctId":"NCT04898283","phase":"PHASE3","title":"Efficacy and Safety Evaluation of the Treatment of Allergy Against Cupressaceae and Grasses.","status":"RECRUITING","sponsor":"Inmunotek S.L.","startDate":"2021-05-31","conditions":"Rhinitis, Allergic, Rhinoconjunctivitis, Asthma, Allergic","enrollment":180},{"nctId":"NCT04891237","phase":"PHASE3","title":"Efficacy and Safety Evaluation for the Treatment of Allergy Against Grass and Olive Pollen","status":"RECRUITING","sponsor":"Inmunotek S.L.","startDate":"2021-06-14","conditions":"Rhinitis, Allergic, Rhinoconjunctivitis, Asthma, Allergic","enrollment":180},{"nctId":"NCT06930950","phase":"NA","title":"The NACHO Trial (Nut Allergy Children OIT)","status":"RECRUITING","sponsor":"HUS Skin and Allergy Hospital","startDate":"2024-09-13","conditions":"Oral Immunotherapy for Food Allergy, Tree Nut Allergy, Cashew Nut Allergy","enrollment":45},{"nctId":"NCT05448066","phase":"NA","title":"Molecular Allergen Component Resolved Diagnosis to Decide Immunotherapy","status":"RECRUITING","sponsor":"Universidade do Porto","startDate":"2022-07-30","conditions":"Asthma, Rhinitis, Allergic","enrollment":210},{"nctId":"NCT06499480","phase":"","title":"Italian Registry of Allergen ImmunoTherapy","status":"RECRUITING","sponsor":"Società Italiana di Allergologia, Asma e Immunologia Clinica","startDate":"2024-05-01","conditions":"Allergic Respiratory Disease","enrollment":5000},{"nctId":"NCT01199133","phase":"PHASE3","title":"Safety and Efficacy Study of Sublingual Immunotherapy (SLIT) to Treat House Dust Mite Allergic Rhinitis in Adolescents and Children","status":"TERMINATED","sponsor":"Stallergenes Greer","startDate":"2009-10","conditions":"Allergic Rhinitis Due to Dust Mite","enrollment":471},{"nctId":"NCT03532360","phase":"NA","title":"Peanut and Tree Nut Desensitization","status":"ACTIVE_NOT_RECRUITING","sponsor":"McGill University Health Centre/Research Institute of the McGill University Health Centre","startDate":"2018-02-19","conditions":"Peanut Allergy, Tree Nut Allergy","enrollment":51},{"nctId":"NCT01527188","phase":"PHASE2","title":"Efficacy and Safety of 100IR, 300IR, 500IR Sublingual House Dust Mite Tablets in Allergic Rhinitis Environment Exposure Chamber Model","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2010-12-08","conditions":"Allergic Rhinitis Due to House Dust Mite","enrollment":355},{"nctId":"NCT06778213","phase":"PHASE4","title":"Evaluation of the Efficacy of Allergen-specific Immunotherapy Using Assessment in an Allergen Exposure chamber-a Randomized Placebo-controlled Double-blind Study","status":"RECRUITING","sponsor":"Wroclaw Medical University","startDate":"2024-11-02","conditions":"Allergic Rhinoconjunctivitis","enrollment":67},{"nctId":"NCT01919554","phase":"PHASE1","title":"Safety Study of Sublingual Immunotherapy Tablets of House Dust Mite Allergen Extracts in Adolescents","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2013-07","conditions":"Allergic Rhinitis Due to House Dust Mite","enrollment":37},{"nctId":"NCT06771934","phase":"","title":"Combination Therapy of Omalizumab and Allergen Immunotherapy for Moderate to Severe Asthma","status":"ACTIVE_NOT_RECRUITING","sponsor":"Qianfoshan Hospital","startDate":"2024-06-01","conditions":"Allergic Asthma","enrollment":60},{"nctId":"NCT03292484","phase":"PHASE3","title":"Longer-term Study of AR101 in Subjects Who Participated in a Prior AR101 Study (ARC008)","status":"COMPLETED","sponsor":"Aimmune Therapeutics, Inc.","startDate":"2017-11-02","conditions":"Peanut Allergy","enrollment":911},{"nctId":"NCT05113394","phase":"PHASE2","title":"Preventing Childhood Asthma Using Prophylactic House Dust Mite Allergen Immunotherapy","status":"WITHDRAWN","sponsor":"Boston Children's Hospital","startDate":"2027-02-01","conditions":"Asthma, Allergy","enrollment":""},{"nctId":"NCT05430919","phase":"PHASE2","title":"Efficacy of the Anti-Bet v 1 Monoclonal Antibodies (Given Subcutaneously) to Reduce Allergic Rhinitis and Conjunctivitis Symptoms and Skin Test Reactivity Upon Exposure to Birch Allergen in Adult Participants","status":"COMPLETED","sponsor":"Regeneron Pharmaceuticals","startDate":"2022-08-15","conditions":"Allergic Rhinitis, Conjunctivitis","enrollment":217},{"nctId":"NCT06061848","phase":"PHASE2, PHASE3","title":"Intralymphatic Immunotherapy Enhanced by Vitamin-D, a Randomized Placebo-controlled Trial and Comparison With SLIT","status":"RECRUITING","sponsor":"Lars Olaf Cardell","startDate":"2023-02-01","conditions":"Allergic Rhinitis Due to Grass Pollen","enrollment":360},{"nctId":"NCT06574061","phase":"","title":"Evaluation of the Benefits of Sublingual AIT (PRACTIS)","status":"COMPLETED","sponsor":"Stallergenes Greer","startDate":"2018-08-29","conditions":"Allergic Rhinitis","enrollment":1635},{"nctId":"NCT06535087","phase":"","title":"The Impact of Airway Allergic Diseases on Children's and Parents' Quality of Life","status":"RECRUITING","sponsor":"Wenjing Zhou","startDate":"2024-07-20","conditions":"Pediatric Asthma, Rhinitis, Allergic, Quality of Life","enrollment":600},{"nctId":"NCT06523478","phase":"NA","title":"Intratonsillar Immunotherapy for Allergic Rhinitis","status":"RECRUITING","sponsor":"Xu Yu","startDate":"2024-04-29","conditions":"Allergic Rhinitis","enrollment":120},{"nctId":"NCT06509243","phase":"NA","title":"Dupilumab and House Dust Mite Immunotherapy in Patients With Atopic Dermatitis","status":"COMPLETED","sponsor":"Medical University of Silesia","startDate":"2023-02-10","conditions":"Atopic Dermatitis","enrollment":132},{"nctId":"NCT03219827","phase":"NA","title":"Pilot Study: Characterization of the Immune Phenotype of Patients Allergic to Wasp Venom or Penicillin","status":"COMPLETED","sponsor":"Institut Pasteur","startDate":"2017-06-13","conditions":"Allergy","enrollment":10},{"nctId":"NCT06038019","phase":"","title":"Thresholds In Food Allergy evaluaTion And predictioN","status":"RECRUITING","sponsor":"Hamilton Health Sciences Corporation","startDate":"2023-11-01","conditions":"Tree Nut Allergy, Food Allergy","enrollment":2000},{"nctId":"NCT04856865","phase":"PHASE1, PHASE2","title":"ADP101 for Oral Immunotherapy in Food-Allergic Children and Adults","status":"COMPLETED","sponsor":"Alladapt Immunotherapeutics, Inc.","startDate":"2021-04-20","conditions":"Food Allergy","enrollment":73},{"nctId":"NCT00135629","phase":"PHASE3","title":"Factors Predicting Efficacy of Allergen Injection Immunotherapy for Grass Pollen Hayfever","status":"COMPLETED","sponsor":"Imperial College London","startDate":"2002-10","conditions":"Rhinitis, Allergic, Seasonal","enrollment":18},{"nctId":"NCT05740163","phase":"NA","title":"Oral Immunotherapy for Egg Allergy in Children Aged 6 to 16","status":"RECRUITING","sponsor":"Tampere University Hospital","startDate":"2019-12-30","conditions":"Egg Allergy","enrollment":60},{"nctId":"NCT05243719","phase":"PHASE1, PHASE2","title":"Open-label Extension Study of ADP101","status":"TERMINATED","sponsor":"Alladapt Immunotherapeutics, Inc.","startDate":"2022-03-14","conditions":"Food Allergy","enrollment":45},{"nctId":"NCT03504774","phase":"PHASE2","title":"Food Allergen OIT for Shrimp and Cashew","status":"TERMINATED","sponsor":"Sayantani B. Sindher","startDate":"2019-07-09","conditions":"Allergy;Food, Allergy to Shrimp, Allergy to Cashew Nut (Disorder)","enrollment":58},{"nctId":"NCT06103656","phase":"PHASE2","title":"E-B-FAHF-2, Multi OIT and Xolair for Food Allergy","status":"COMPLETED","sponsor":"New York Medical College","startDate":"2016-08-20","conditions":"Food Allergy","enrollment":33},{"nctId":"NCT06151938","phase":"","title":"Evaluate Measurement Instruments Relevance in Assessing Effectiveness of ACARIZAX® in House Dust Mite Allergic Rhinitis","status":"ENROLLING_BY_INVITATION","sponsor":"ALK-Abelló A/S","startDate":"2023-11-21","conditions":"Allergic Rhinitis Due to House Dust Mite, Allergic Asthma","enrollment":100},{"nctId":"NCT05753241","phase":"","title":"the Relationship Between Allergic Rhinitis and the Risk of Symptom in Patients With Mild COVID-19","status":"COMPLETED","sponsor":"qinxiu zhang","startDate":"2022-11-10","conditions":"COVID-19, Allergic Rhinitis","enrollment":1100},{"nctId":"NCT05641272","phase":"PHASE2, PHASE3","title":"Clinical Trial to Evaluate the Efficacy and Safety of Polymerized, Mannan-Conjugated Dermatophagoides Allergen Extract","status":"NOT_YET_RECRUITING","sponsor":"Inmunotek S.L.","startDate":"2023-11-01","conditions":"Allergic Rhinitis, Allergic Asthma, Allergic Rhinoconjunctivitis","enrollment":90},{"nctId":"NCT04222491","phase":"PHASE2","title":"Food Oral Immunotherapy for Peanut Allergy","status":"ENROLLING_BY_INVITATION","sponsor":"Massachusetts General Hospital","startDate":"2020-06-25","conditions":"Peanut Allergy","enrollment":500},{"nctId":"NCT06027073","phase":"PHASE4","title":"Biologics and Sublingual Immunotherapy","status":"NOT_YET_RECRUITING","sponsor":"Medical University of Silesia","startDate":"2024-05-01","conditions":"Asthma, Allergic","enrollment":150},{"nctId":"NCT06021912","phase":"","title":"e-ITAG Allergen Immunotherapy in the Management of Allergic Asthma","status":"UNKNOWN","sponsor":"General Administration of Military Health, Tunisia","startDate":"2023-03-01","conditions":"Study the Efficacy of ITA in Patients With Allergic Asthma or Allergic Rhinitis or Allergic Rhinitis Compared With Conventional Treatment","enrollment":300},{"nctId":"NCT03541187","phase":"PHASE2","title":"Cockroach Immunotherapy in Children and Adolescents","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2018-07-16","conditions":"Persistent Asthma","enrollment":82},{"nctId":"NCT04100122","phase":"","title":"Luminex-based Assay to Identify Major IgE-binding Episode Among IgE-mediated Wheat-allergic Patient","status":"COMPLETED","sponsor":"Mahidol University","startDate":"2019-09-13","conditions":"Wheat Allergy","enrollment":100},{"nctId":"NCT05821621","phase":"","title":"Efficacy and Safety of Cashew Nut Oral Immunotherapy in Children","status":"UNKNOWN","sponsor":"Central Hospital, Nancy, France","startDate":"2023-04-17","conditions":"Food Allergy in Children","enrollment":50},{"nctId":"NCT05786638","phase":"NA","title":"Efficacy of Sublingual Versus Subcutaneous Allergen Immunotherapy in Patients With Bronchial Asthma","status":"COMPLETED","sponsor":"Mansoura University Hospital","startDate":"2021-10-20","conditions":"Efficacy, Self","enrollment":100},{"nctId":"NCT01134757","phase":"NA","title":"Safety of Bronchial Allergen Challenge and Predictors for Positive Reaction.","status":"COMPLETED","sponsor":"Johann Wolfgang Goethe University Hospital","startDate":"2011-01","conditions":"House Dust Mite Allergy, Bronchial Hyperresponsiveness","enrollment":425},{"nctId":"NCT03736447","phase":"PHASE3","title":"Peanut Oral Immunotherapy Study of Early Intervention for Desensitization","status":"COMPLETED","sponsor":"Aimmune Therapeutics, Inc.","startDate":"2018-12-27","conditions":"Peanut Allergy","enrollment":146},{"nctId":"NCT04813380","phase":"PHASE3","title":"Serum MicroRNAs 223 and 146a in Allergic Rhinitis Patients as Biomarkers for Efficacy of Sublingual Immunotherapy","status":"COMPLETED","sponsor":"Zagazig University","startDate":"2021-07-27","conditions":"Effects of Immunotherapy","enrollment":64},{"nctId":"NCT04200989","phase":"PHASE1, PHASE2","title":"Novel Treatment for Patients With Peanut Allergy: Intralymphatic Immunotherapy","status":"WITHDRAWN","sponsor":"Scripps Health","startDate":"2021-03-01","conditions":"Food Allergy Peanut","enrollment":""},{"nctId":"NCT05621356","phase":"","title":"Monitoring Allergen Immunotherapy in Allergic Rhinitis","status":"UNKNOWN","sponsor":"Rijnstate Hospital","startDate":"2022-10-25","conditions":"Immunotherapy, Rhinitis, Allergic, Treatment Outcome","enrollment":25},{"nctId":"NCT05400811","phase":"PHASE3","title":"Efficacy and Safety Evaluation for the Treatment of HDM Induced Allergic Asthma and Rhinitis/Rhinoconjunctivitis","status":"UNKNOWN","sponsor":"Inmunotek S.L.","startDate":"2022-12","conditions":"House Dust Mite Allergy, Perennial Allergic Rhinitis, Allergic Rhinoconjunctivitis","enrollment":400},{"nctId":"NCT05570383","phase":"PHASE2, PHASE3","title":"Observation on the Efficacy and Mechanism of SLIT With Dust Mite Allergen for PAR","status":"UNKNOWN","sponsor":"People's Hospital of Anshun City of Guizhou Province","startDate":"2022-12-01","conditions":"Allergic Rhinitis","enrollment":60},{"nctId":"NCT04296474","phase":"PHASE1, PHASE2","title":"Follow up Study 5-6 Years After ILIT With 2 Concomitant Allergens, Birch and Grass","status":"COMPLETED","sponsor":"Lars Olaf Cardell","startDate":"2018-05-15","conditions":"Allergic Rhinitis","enrollment":34},{"nctId":"NCT05510024","phase":"NA","title":"Radiofrequency Ablation of Bilateral Inferior Turbinate Followed by Subcutaneous Immunotherapy Trial","status":"NOT_YET_RECRUITING","sponsor":"Eye & ENT Hospital of Fudan University","startDate":"2022-10-01","conditions":"Allergic Rhinitis Due to House Dust Mite","enrollment":392},{"nctId":"NCT05450289","phase":"NA","title":"The Efficacy of Nigella Sativa in Children With House Dust Mite-Induced Respiratory Allergy Receiving Immunotherapy","status":"UNKNOWN","sponsor":"Universitas Airlangga","startDate":"2022-08","conditions":"House Dust Mite Allergy","enrollment":40},{"nctId":"NCT02975479","phase":"PHASE2, PHASE3","title":"Intralymphatic Immunotherapy in Increasing Doses, Substudy","status":"COMPLETED","sponsor":"Karolinska Institutet","startDate":"2016-05","conditions":"Rhinitis, Allergic, Seasonal","enrollment":40},{"nctId":"NCT05318157","phase":"PHASE4","title":"Efficacy of Artemisia Pollen Specific Allergen Immunotherapy","status":"UNKNOWN","sponsor":"Beijing Tongren Hospital","startDate":"2022-03-31","conditions":"Allergic Rhinitis","enrollment":150},{"nctId":"NCT04100902","phase":"PHASE4","title":"The Effect of Allergen Immunotherapy on Anti-viral Immunity in Patients With Allergic Asthma","status":"COMPLETED","sponsor":"Bispebjerg Hospital","startDate":"2020-01-20","conditions":"Allergic Asthma Due to Dermatophagoides Pteronyssinus","enrollment":39},{"nctId":"NCT04104828","phase":"","title":"Comparison of Innate Immune Responses Induced by Allergy Immunotherapy (AIT) With Different Adjuvants","status":"COMPLETED","sponsor":"University of Zurich","startDate":"2019-11-05","conditions":"Allergic Rhinitis","enrollment":24},{"nctId":"NCT02676765","phase":"PHASE3","title":"Desensitization and Cross-Desensitization During Oral Grass or Ragweed Pollen Immunotherapy","status":"TERMINATED","sponsor":"Virginia Commonwealth University","startDate":"2016-06","conditions":"Immunologic Desensitization","enrollment":58},{"nctId":"NCT05009134","phase":"","title":"Influences of Allergic Rhinitis and Allergen Immunotherapy on SARS-CoV-2 Vaccination","status":"UNKNOWN","sponsor":"Huazhong University of Science and Technology","startDate":"2021-06-04","conditions":"Allergic Rhinitis, Allergen Immunotherapy, SARS-CoV-2","enrollment":120},{"nctId":"NCT02635776","phase":"PHASE3","title":"Peanut Allergy Oral Immunotherapy Study of AR101 for Desensitization in Children and Adults (PALISADE)","status":"COMPLETED","sponsor":"Aimmune Therapeutics, Inc.","startDate":"2015-12-22","conditions":"Peanut Allergy","enrollment":555},{"nctId":"NCT02993107","phase":"PHASE3","title":"PALISADE Follow-on Study (ARC004)","status":"COMPLETED","sponsor":"Aimmune Therapeutics, Inc.","startDate":"2016-12-29","conditions":"Peanut Allergy","enrollment":388},{"nctId":"NCT04056299","phase":"PHASE2","title":"Oral Immunotherapy for Desensitization in Children, Adolescents, and Young Adults With Hen Egg Allergy","status":"TERMINATED","sponsor":"Aimmune Therapeutics, Inc.","startDate":"2019-08-20","conditions":"Hen Egg Allergy","enrollment":15},{"nctId":"NCT02654223","phase":"PHASE2","title":"Dose Finding for the Treatment of Rhinitis/Rhinoconjunctivitis Against Grass Pollen Allergy","status":"COMPLETED","sponsor":"Inmunotek S.L.","startDate":"2015-12-30","conditions":"Rhinitis, Rhinoconjunctivitis","enrollment":180},{"nctId":"NCT01987817","phase":"PHASE2","title":"Oral Desensitization to Peanut in Peanut-Allergic Children and Adults Using Characterized Peanut Allergen OIT","status":"COMPLETED","sponsor":"Aimmune Therapeutics, Inc.","startDate":"2014-02-06","conditions":"Peanut Allergy","enrollment":56},{"nctId":"NCT02198664","phase":"PHASE2","title":"Oral Desensitization to Peanut in Peanut Allergic Children and Adults Using CPNA Peanut OIT Safety Follow-On Study","status":"COMPLETED","sponsor":"Aimmune Therapeutics, Inc.","startDate":"2014-08-27","conditions":"Peanut Allergy","enrollment":47},{"nctId":"NCT03126227","phase":"PHASE3","title":"Real-World AR101 Market-Supporting Experience Study in Peanut-Allergic Children (RAMSES)","status":"COMPLETED","sponsor":"Aimmune Therapeutics, Inc.","startDate":"2017-05-08","conditions":"Peanut Allergy","enrollment":506},{"nctId":"NCT03337542","phase":"PHASE3","title":"AR101 Real-World Open-Label Extension Study","status":"COMPLETED","sponsor":"Aimmune Therapeutics, Inc.","startDate":"2017-10-18","conditions":"Peanut Allergy","enrollment":243},{"nctId":"NCT03821077","phase":"","title":"Study to Evaluate the Efficacy and Safety of \"Allergovac Poliplus\" in Polysensitized Patients With Allergic Rhinitis/Rhinoconjunctivitis, With or Without Asthma","status":"COMPLETED","sponsor":"Roxall Medicina España S.A","startDate":"2018-08-30","conditions":"Rhinitis, Allergic, Rhinoconjunctivitis","enrollment":122}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2850,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"Allergen immunotherapy","genericName":"Allergen immunotherapy","companyName":"Rohr and Columbo Asthma, Allergy and Immunology Specialists, P.C.","companyId":"rohr-and-columbo-asthma-allergy-and-immunology-specialists-p-c","modality":"Biologic","firstApprovalDate":"","aiSummary":"Allergen immunotherapy works by gradually increasing exposure to specific allergens to build tolerance and reduce symptoms. Used for Treatment of allergic rhinitis and asthma.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}