{"id":"alk-tree-ait-12-du","_chembl":null,"modality":"Biologic","_dailymed":null,"mechanism":{"explanation":"The product likely works through gradual exposure to allergen extracts to induce immune tolerance, reducing allergic responses over time. This approach typically modulates T-cell responses and promotes regulatory immune pathways.","oneSentence":"Allergen immunotherapy designed to desensitize the immune system through controlled exposure to specific allergens."},"_scrapedAt":"2026-03-28T03:21:03.002Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"_claudeStub":{"ts":1779123078,"model":"claude-sonnet-4-5-20250929"},"competitors":[{"name":"Ragwitek","brand":"Ragwitek","company":"ALK-Abelló A/S","rationale":"Sublingual allergy immunotherapy tablet for ragweed allergy"},{"name":"Grastek","brand":"Grastek","company":"ALK-Abelló A/S","rationale":"Sublingual allergy immunotherapy tablet for grass pollen allergy"},{"name":"Palforzia","brand":"Palforzia","company":"Aimmune Therapeutics","rationale":"Oral immunotherapy for peanut allergy desensitization"}],"description":"ALK tree AIT 12 DU is an investigational allergy immunotherapy product developed by ALK-Abelló A/S, currently in Phase 2 clinical development. The product appears to be part of ALK-Abelló's allergy immunotherapy portfolio, though specific details about its formulation and target allergens are limited.","indications":{"approved":[{"status":"investigational","condition":"Allergic conditions","patientPopulation":"Adults and potentially pediatric patients with specific allergies"}]},"trialDetails":[{"nctId":"NCT01675791","phase":"PHASE2","title":"A Dose-response Evaluation of ALK (the Sponsor) Tree Allergy Immunotherapy Tablet","status":"COMPLETED","sponsor":"ALK-Abelló A/S","startDate":"2012-08","conditions":"Birch Pollen Allergy","enrollment":637}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"ALK tree AIT 12 DU","genericName":"ALK tree AIT 12 DU","companyName":"ALK-Abelló A/S","companyId":"alk-abell-a-s","firstApprovalDate":"","aiSummary":"","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}