{"id":"alk-hdm-ait-6-du","safety":{"commonSideEffects":[{"rate":null,"effect":"Local injection site reactions (erythema, swelling, pruritus)"},{"rate":null,"effect":"Systemic allergic reactions"},{"rate":null,"effect":"Rhinitis symptoms"},{"rate":null,"effect":"Asthma exacerbation"}]},"_chembl":{"chemblId":"CHEMBL1162127","moleculeType":"Small molecule","molecularWeight":"669.01"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This is an allergy immunotherapy product containing modified house dust mite allergen extracts designed to induce immune tolerance. By gradually exposing patients to increasing doses of HDM allergens, the treatment shifts the immune response from IgE-mediated hypersensitivity toward IgG-mediated tolerance and regulatory T cell activation, reducing allergic symptoms and airway hyperresponsiveness.","oneSentence":"ALK HDM AIT 6 DU is an allergen immunotherapy (AIT) vaccine that desensitizes the immune system to house dust mite (HDM) allergens through repeated subcutaneous administration.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:00:43.246Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"House dust mite allergic rhinitis and/or asthma"}]},"trialDetails":[{"nctId":"NCT01433523","phase":"PHASE3","title":"House Dust Mite Treatment of Asthma. The MITRA Trial House Dust Mite Treatment of Asthma","status":"COMPLETED","sponsor":"ALK-Abelló A/S","startDate":"2011-08","conditions":"Asthma","enrollment":834}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"ALK HDM AIT 6 DU","genericName":"ALK HDM AIT 6 DU","companyName":"ALK-Abelló A/S","companyId":"alk-abell-a-s","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ALK HDM AIT 6 DU is an allergen immunotherapy (AIT) vaccine that desensitizes the immune system to house dust mite (HDM) allergens through repeated subcutaneous administration. Used for House dust mite allergic rhinitis and/or asthma.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}