{"id":"alk-grass-tablet","safety":{"commonSideEffects":[{"rate":null,"effect":"Oral pruritus"},{"rate":null,"effect":"Throat irritation"},{"rate":null,"effect":"Mouth edema"},{"rate":null,"effect":"Local allergic reactions at administration site"}]},"_chembl":{"chemblId":"CHEMBL1162127","moleculeType":"Small molecule","molecularWeight":"669.01"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This sublingual immunotherapy tablet contains standardized grass pollen allergen extract designed to induce immune tolerance. By administering small, gradually increasing doses of the allergen under the tongue, the treatment shifts the immune response from allergic (Th2-mediated) to tolerant (Th1/Treg-mediated), reducing allergic symptoms upon natural grass pollen exposure.","oneSentence":"ALK Grass tablet is an allergen immunotherapy that desensitizes the immune system to grass pollen allergens through gradual exposure.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:00:46.337Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Grass pollen-induced allergic rhinitis and/or allergic asthma"}]},"trialDetails":[{"nctId":"NCT06061848","phase":"PHASE2, PHASE3","title":"Intralymphatic Immunotherapy Enhanced by Vitamin-D, a Randomized Placebo-controlled Trial and Comparison With SLIT","status":"RECRUITING","sponsor":"Lars Olaf Cardell","startDate":"2023-02-01","conditions":"Allergic Rhinitis Due to Grass Pollen","enrollment":360},{"nctId":"NCT01889875","phase":"NA","title":"Immunological Comparison of AIT and SCIT Immunotherapy Against Grass Pollen","status":"COMPLETED","sponsor":"Bispebjerg Hospital","startDate":"2010-11","conditions":"Allergic Rhinitis Due to Grass Pollens","enrollment":40},{"nctId":"NCT00227279","phase":"PHASE3","title":"A Trial of the ALK Grass Tablet in Subjects With Hayfever","status":"COMPLETED","sponsor":"ALK-Abelló A/S","startDate":"2004-10","conditions":"Allergy","enrollment":634},{"nctId":"NCT00293046","phase":"PHASE3","title":"Assessment of Grazax® Treatment Compliance","status":"COMPLETED","sponsor":"ALK-Abelló A/S","startDate":"2006-02","conditions":"Allergy","enrollment":500},{"nctId":"NCT00413556","phase":"PHASE3","title":"Changes in the Immune Response and Skin Reactivity of Grass Pollen Allergic Patients Treated With ALK Grass Tablets","status":"COMPLETED","sponsor":"ALK-Abelló A/S","startDate":"2007-01","conditions":"Allergy","enrollment":76},{"nctId":"NCT00298701","phase":"PHASE1","title":"Tolerability of Grazax-R in Children","status":"COMPLETED","sponsor":"ALK-Abelló A/S","startDate":"2006-02","conditions":"Allergy","enrollment":50},{"nctId":"NCT00310453","phase":"PHASE1","title":"Tolerability of ALK Grass Tablet in Children","status":"COMPLETED","sponsor":"ALK-Abelló A/S","startDate":"2006-03","conditions":"Allergy","enrollment":32}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"ALK Grass tablet","genericName":"ALK Grass tablet","companyName":"ALK-Abelló A/S","companyId":"alk-abell-a-s","modality":"Biologic","firstApprovalDate":"","aiSummary":"ALK Grass tablet is an allergen immunotherapy that desensitizes the immune system to grass pollen allergens through gradual exposure. Used for Grass pollen-induced allergic rhinitis and/or allergic asthma.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}