{"id":"alfadolone-acetate","rwe":[],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Anesthetics","category":"pharmacology"},{"label":"Central Nervous System Agents","category":"pharmacology"},{"label":"Central Nervous System Depressants","category":"pharmacology"},{"label":"Neurosteroids","category":"pharmacology"},{"label":"Neurotransmitter Agents","category":"pharmacology"}],"phase":"unknown","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"_fixedAt":"2026-03-30T16:30:33.042069","allNames":"alphadolone acetate","offLabel":[],"synonyms":["alphadolone acetate","alfadolone acetate"],"timeline":[],"brandName":"Alphadolone Acetate","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells have locks on them, and Alphadolone Acetate is a key that fits into those locks. When it binds to the lock, it sends a signal to the cell to do something specific, like reducing inflammation or suppressing an immune response. This is a simplified explanation of how Alphadolone Acetate works at a molecular level.","oneSentence":"Alphadolone Acetate works by interacting with specific receptors in the body to produce a desired therapeutic effect.","technicalDetail":"Alphadolone Acetate is a synthetic steroid that likely acts as an agonist or antagonist at specific nuclear receptors, influencing gene expression and cellular function."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Alfadolone","title":"Alfadolone","extract":"Alfadolone (INN), or alphadolone is a neuroactive steroid and general anesthetic. Along with alfaxolone, as alfadolone acetate, it is one of the components of the anesthetic drug mixture althesin."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/5045","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=alfadolone acetate","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Alfadolone","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T08:36:30.227402","biosimilars":[],"competitors":[],"genericName":"alfadolone acetate","indications":{"approved":[],"offLabel":[],"pipeline":[]},"_fixedFields":["pubmed(2)"],"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"00TN4GS00S","CHEBI":"CHEBI:92901","INN_ID":"3216","UMLSCUI":"C0051481","ChEMBL_ID":"CHEMBL2104019","PUBCHEM_CID":"24733","SNOMEDCT_US":"125707004","SECONDARY_CAS_RN":"14107-37-0","MESH_SUPPLEMENTAL_RECORD_UI":"C033418"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":2,"therapeuticAreas":["Immunology"],"biosimilarFilings":[],"recentPublications":[{"date":"1983 Jan","pmid":"6828225","title":"Althesin in the management of head injuries: a preliminary report.","journal":"Neurosurgery"},{"date":"1979 Apr","pmid":"434539","title":"Porphyrin-inducing activity of alfaxolone and alfadolone acetate in chick embryo liver cells.","journal":"Anesthesiology"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Alphadolone Acetate, also known as alfadolone acetate, is a synthetic steroid with a complex mechanism of action. However, due to the lack of available information, a comprehensive summary cannot be provided. It is not clear what specific condition or disease it targets, nor its exact pharmacological class. Alphadolone Acetate is a small molecule, but its commercial status and safety considerations are unknown. Further research is needed to understand its clinical applications and potential risks.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}