{"id":"ald-401","safety":{"commonSideEffects":[{"rate":"null","effect":"Injection site reaction"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"ALD-401 is a type of cell therapy that utilizes a patient's own stem cells to stimulate the repair and regeneration of damaged tissues. This is achieved through the administration of a specific type of stem cell that has been shown to have regenerative properties.","oneSentence":"ALD-401 is a stem cell therapy that aims to promote tissue repair and regeneration.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T03:20:52.597Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Ischemic heart failure"}]},"trialDetails":[{"nctId":"NCT01273337","phase":"PHASE2","title":"Study of ALD-401 Via Intracarotid Infusion in Ischemic Stroke Subjects","status":"UNKNOWN","sponsor":"Aldagen","startDate":"2011-03","conditions":"Stroke, Ischemic Stroke, Stroke in Middle Cerebral Artery (MCA)","enrollment":100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["ALDHbr cells","ALDH Bright cells"],"phase":"phase_2","status":"active","brandName":"ALD-401","genericName":"ALD-401","companyName":"Aldagen","companyId":"aldagen","modality":"Biologic","firstApprovalDate":"","aiSummary":"ALD-401 is a treatment being studied for stroke, ischemic stroke, and stroke in the middle cerebral artery (MCA). It is administered via intracarotid infusion in a randomized, controlled study.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}