{"id":"alc-2203-ac","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Nausea"},{"rate":"5-10%","effect":"Dizziness"},{"rate":"5-10%","effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Activation of the kappa opioid receptor is thought to produce analgesia with a lower risk of respiratory depression compared to mu opioid receptor agonists. This receptor is also implicated in the regulation of stress and anxiety responses.","oneSentence":"ALC-2203-AC is a selective and potent agonist of the kappa opioid receptor.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:20:51.598Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Chronic pain"}]},"trialDetails":[{"nctId":"NCT07061925","phase":"PHASE2","title":"To Evaluate the Efficacy and Safety of ALC-2203 in Patients With Acute Bronchitis","status":"COMPLETED","sponsor":"Korea Arlico Pharm. Co., Ltd","startDate":"2025-04-23","conditions":"Acute Bronchitis","enrollment":169}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"ALC-2203-AC","genericName":"ALC-2203-AC","companyName":"Korea Arlico Pharm. Co., Ltd","companyId":"korea-arlico-pharm-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ALC-2203-AC is a selective and potent agonist of the kappa opioid receptor. Used for Chronic pain.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}