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Carboplatin, on the other hand, works by cross-linking DNA, which prevents the replication of DNA and transcription of RNA, ultimately leading to cell death.","oneSentence":"Albumin paclitaxel is a formulation of paclitaxel, a microtubule inhibitor, which works by binding to tubulin and preventing the formation of microtubules, thereby inhibiting cell division. Carboplatin is a platinum-based chemotherapy drug that works by cross-linking DNA, thereby inhibiting cell division.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:20:39.852Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Non-small cell lung cancer"}]},"trialDetails":[{"nctId":"NCT03907475","phase":"PHASE2","title":"Durvalumab in Combination With Chemotherapy in Treating Patients With Advanced Solid Tumors, DURVA+ Trial","status":"RECRUITING","sponsor":"National Cancer Institute (NCI)","startDate":"2019-07-16","conditions":"Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm","enrollment":115},{"nctId":"NCT06841354","phase":"PHASE3","title":"A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)","status":"RECRUITING","sponsor":"Merck Sharp & Dohme 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