{"id":"albumin-electrolyte-solution","safety":{"commonSideEffects":[{"rate":null,"effect":"Hypervolemia / fluid overload"},{"rate":null,"effect":"Hypernatremia"},{"rate":null,"effect":"Allergic reactions"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Hypotension"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Albumin is a major plasma protein that maintains oncotic pressure and serves as a carrier for various substances; when combined with an electrolyte solution, it replaces both the protein and ionic components lost during hemorrhage, severe burns, or other conditions causing fluid depletion. The electrolyte component restores sodium, potassium, chloride, and other ions necessary for normal cellular and cardiovascular function. This combination is used for volume resuscitation and nutritional support in critically ill patients.","oneSentence":"This product provides albumin protein and essential electrolytes to restore intravascular volume and maintain electrolyte balance in patients with fluid loss or hypoproteinemia.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:26:56.923Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Hypovolemia and hypoproteinemia in critically ill patients"},{"name":"Volume replacement in severe burns"},{"name":"Hemorrhagic shock"},{"name":"Perioperative fluid management"}]},"trialDetails":[{"nctId":"NCT04894643","phase":"NA","title":"Preoperative, Proton- Radiotherapy Combined With Chemotherapy for Borderline Resectable Pancreatic Cancer","status":"RECRUITING","sponsor":"EBG MedAustron GmbH","startDate":"2020-09-14","conditions":"Pancreatic Cancer, Proton Therapy","enrollment":10},{"nctId":"NCT05059795","phase":"","title":"Volume Resuscitation in Cirrhosis With Sepsis Induced Hypotension","status":"COMPLETED","sponsor":"Post Graduate Institute of Medical Education and Research, Chandigarh","startDate":"2020-02-01","conditions":"Cirrhosis, Liver, Sepsis, Acute on Chronic Liver Failure","enrollment":350},{"nctId":"NCT03668236","phase":"PHASE4","title":"The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial","status":"COMPLETED","sponsor":"Anders Perner, MD, PhD","startDate":"2018-11-27","conditions":"Septic Shock","enrollment":1554},{"nctId":"NCT03507062","phase":"NA","title":"Effect of Crystalloids With Different SID on pH, and Urinary Electrolytes During General Anesthesia","status":"COMPLETED","sponsor":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","startDate":"2017-12-10","conditions":"SID, Acid-Base Imbalance","enrollment":45},{"nctId":"NCT06236958","phase":"","title":"Effect of Early Enteral Nutrition on Postoperative Recovery of Ovarian Cancer Patients","status":"UNKNOWN","sponsor":"Luo Chengyan","startDate":"2023-12-01","conditions":"Advanced Epithelial Ovarian Cancer","enrollment":200},{"nctId":"NCT02837094","phase":"PHASE1","title":"Enhanced Epidermal Antigen Specific Immunotherapy Trial -1","status":"COMPLETED","sponsor":"Cardiff University","startDate":"2016-09-29","conditions":"Type 1 Diabetes","enrollment":6},{"nctId":"NCT05076435","phase":"PHASE2","title":"Restrictive Fluid Administration vs. Standard of Care in Emergency Department Sepsis Patients","status":"COMPLETED","sponsor":"Marie Kristine Jessen, MD","startDate":"2021-11-03","conditions":"Sepsis","enrollment":124},{"nctId":"NCT05033704","phase":"NA","title":"Effect of Human Plasma Protein Transfusion With and Without Crystalloids During Major Liver Resection Surgeries","status":"UNKNOWN","sponsor":"Hamad Medical Corporation","startDate":"2019-09-09","conditions":"Coagulation; Intravascular, Fluid Electrolyte Disorders","enrollment":48},{"nctId":"NCT02560519","phase":"PHASE4","title":"Albumin in Cardiac Surgery","status":"COMPLETED","sponsor":"Helsinki University Central Hospital","startDate":"2017-03-21","conditions":"C.Surgical Procedure; Cardiac","enrollment":1386},{"nctId":"NCT03801135","phase":"NA","title":"Changes in Haemostasis After Therapeutic Plasmapheresis With Citrate Anticoagulation","status":"UNKNOWN","sponsor":"University Medical Centre Ljubljana","startDate":"2018-10-03","conditions":"Humoral Rejection, Guillain-Barre Syndrome, Miller Fisher Syndrome","enrollment":20},{"nctId":"NCT01553617","phase":"PHASE4","title":"VolulyteTM in Cardiac Surgery","status":"COMPLETED","sponsor":"Fresenius Kabi","startDate":"2012-10","conditions":"Heart; Dysfunction Postoperative, Cardiac Surgery","enrollment":133},{"nctId":"NCT01689506","phase":"PHASE4","title":"Fluid Resuscitation in Patients Suffering From Burns Injury","status":"TERMINATED","sponsor":"Fresenius Kabi","startDate":"2012-12","conditions":"Burns","enrollment":11},{"nctId":"NCT00936247","phase":"PHASE4","title":"Tetraspan 6 Percent (%) Combined With Sterofundin ISO Versus Albumin 5 Percent (%) Combined With Sodium Chloride (NaCL)","status":"TERMINATED","sponsor":"B. Braun Melsungen AG","startDate":"2009-11","conditions":"Renal Insufficiency","enrollment":2}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":10,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Crystalloid"],"phase":"marketed","status":"active","brandName":"Albumin + electrolyte solution","genericName":"Albumin + electrolyte solution","companyName":"B. Braun Melsungen AG","companyId":"b-braun-melsungen-ag","modality":"Small molecule","firstApprovalDate":"","aiSummary":"This product provides albumin protein and essential electrolytes to restore intravascular volume and maintain electrolyte balance in patients with fluid loss or hypoproteinemia. Used for Hypovolemia and hypoproteinemia in critically ill patients, Volume replacement in severe burns, Hemorrhagic shock.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}