{"id":"agspt201-tab-contains-s-pantoprazole","safety":{"commonSideEffects":[{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Diarrhea"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Abdominal pain"},{"rate":null,"effect":"Constipation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"S-pantoprazole is the active S-enantiomer of pantoprazole, a proton pump inhibitor (PPI) that irreversibly binds to and blocks the H+/K+-ATPase enzyme in the gastric mucosa. This reduces intragastric acid production, providing relief from acid-related gastrointestinal conditions. The S-enantiomer is the pharmacologically active form responsible for acid suppression.","oneSentence":"S-pantoprazole inhibits the proton pump in gastric parietal cells, reducing gastric acid secretion.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T01:00:15.053Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Gastroesophageal reflux disease (GERD)"},{"name":"Peptic ulcer disease"},{"name":"Acid-related gastrointestinal disorders"}]},"trialDetails":[{"nctId":"NCT01400945","phase":"PHASE3","title":"Efficacy Study of AGSPT201 Tablet to Treat Gastroesophageal Reflux Disease","status":"COMPLETED","sponsor":"Ahn-Gook Pharmaceuticals Co.,Ltd","startDate":"2009-12","conditions":"Gastroesophageal Reflux Disease","enrollment":154}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["AGSPT201 Tab. (Brand name Deflux tab)"],"phase":"phase_3","status":"active","brandName":"AGSPT201 Tab contains S-pantoprazole","genericName":"AGSPT201 Tab contains S-pantoprazole","companyName":"Ahn-Gook Pharmaceuticals Co.,Ltd","companyId":"ahn-gook-pharmaceuticals-co-ltd","modality":"Small molecule","firstApprovalDate":"","aiSummary":"S-pantoprazole inhibits the proton pump in gastric parietal cells, reducing gastric acid secretion. Used for Gastroesophageal reflux disease (GERD), Peptic ulcer disease, Acid-related gastrointestinal disorders.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}