{"id":"agn-210961-formulation-6","safety":{"commonSideEffects":[{"rate":null,"effect":"Testosterone suppression"},{"rate":null,"effect":"Liver enzyme elevation"},{"rate":null,"effect":"Lipid profile changes"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"SARMs like AGN-210961 bind to androgen receptors with selectivity for certain tissues, aiming to deliver anabolic benefits (muscle, bone) while minimizing unwanted androgenic side effects in other tissues. This tissue selectivity is intended to improve the therapeutic window compared to traditional androgens or non-selective compounds.","oneSentence":"AGN-210961 is a selective androgen receptor modulator (SARM) designed to provide tissue-selective androgenic effects.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T03:20:20.534Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Muscle wasting or sarcopenia (investigational)"},{"name":"Bone health / osteoporosis (investigational)"}]},"trialDetails":[{"nctId":"NCT01110499","phase":"PHASE2","title":"Safety and Efficacy of AGN-210961 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension","status":"COMPLETED","sponsor":"Allergan","startDate":"2010-06","conditions":"Ocular Hypertension, Primary Open-Angle Glaucoma","enrollment":163}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":3,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"AGN-210961 Formulation 6","genericName":"AGN-210961 Formulation 6","companyName":"Allergan","companyId":"allergan","modality":"Small molecule","firstApprovalDate":"","aiSummary":"AGN-210961 is a selective androgen receptor modulator (SARM) designed to provide tissue-selective androgenic effects. Used for Muscle wasting or sarcopenia (investigational), Bone health / osteoporosis (investigational).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}