{"id":"agn-210669-ophthalmic-solution-0-1","safety":{"commonSideEffects":[{"rate":"null","effect":"Increased intraocular pressure"}]},"_chembl":{"chemblId":"CHEMBL4303670","moleculeType":"Small molecule","molecularWeight":"424.57"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"Corticosteroids like AGN-210669 work by inhibiting the production of inflammatory mediators, such as prostaglandins and leukotrienes, which contribute to the inflammatory response. This leads to a reduction in swelling, redness, and pain in the affected area. AGN-210669 is administered topically to the eye to minimize systemic side effects.","oneSentence":"AGN-210669 ophthalmic solution is a corticosteroid used to reduce inflammation in the eye.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:20:13.205Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of noninfectious uveitis affecting the posterior segment of the eye"}]},"trialDetails":[{"nctId":"NCT01001195","phase":"PHASE2","title":"Safety and Efficacy of Three Formulations of AGN-210669 Ophthalmic Solution Compared With Bimatoprost Ophthalmic Solution","status":"COMPLETED","sponsor":"Allergan","startDate":"2009-11","conditions":"Glaucoma, Open-Angle, Ocular Hypertension","enrollment":165}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":39,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"AGN-210669 ophthalmic solution, 0.1%","genericName":"AGN-210669 ophthalmic solution, 0.1%","companyName":"Allergan","companyId":"allergan","modality":"Small molecule","firstApprovalDate":"","aiSummary":"AGN-210669 ophthalmic solution is a corticosteroid used to reduce inflammation in the eye. Used for Treatment of noninfectious uveitis affecting the posterior segment of the eye.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}