{"id":"aggressive-iron-dextran-supplementation","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site reactions (pain, inflammation)"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Dizziness"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Hypersensitivity reactions"},{"rate":null,"effect":"Arthralgia"}]},"_chembl":{"chemblId":"CHEMBL1201544","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Iron dextran is a parenteral iron replacement therapy consisting of ferric iron complexed with dextran, allowing intravenous or intramuscular administration. The iron is released from the dextran complex and incorporated into hemoglobin and other iron-dependent proteins, correcting iron deficiency anemia. 'Aggressive supplementation' refers to higher-dose or more frequent dosing regimens to rapidly restore iron stores.","oneSentence":"Iron dextran is a colloidal iron-carbohydrate complex that replenishes depleted iron stores by providing bioavailable iron for hemoglobin synthesis.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:26:51.755Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Iron deficiency anemia"},{"name":"Iron deficiency anemia in patients unable to tolerate or absorb oral iron"}]},"trialDetails":[{"nctId":"NCT02731378","phase":"PHASE4","title":"Erythropoietin and Iron Supplementation for Patients With Chemotherapy-induced Anaemia","status":"UNKNOWN","sponsor":"Shanghai East Hospital","startDate":"2016-12","conditions":"Chemotherapy-induced Anaemia","enrollment":603}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Aggressive iron dextran supplementation","genericName":"Aggressive iron dextran supplementation","companyName":"Shanghai East Hospital","companyId":"shanghai-east-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Iron dextran is a colloidal iron-carbohydrate complex that replenishes depleted iron stores by providing bioavailable iron for hemoglobin synthesis. Used for Iron deficiency anemia, Iron deficiency anemia in patients unable to tolerate or absorb oral iron.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}