{"id":"adrenalone","rwe":[{"pmid":"40876091","year":"2026","title":"Hydrogel-based drug delivery system designed for chemotherapy-induced alopecia.","finding":"","journal":"Biomaterials advances","studyType":"Clinical Study"},{"pmid":"39229547","year":"2024","title":"Study on the uptake of Gastrodin in the liver.","finding":"","journal":"Heliyon","studyType":"Clinical Study"},{"pmid":"37857579","year":"2023","title":"Highly Enantioselective Synthesis of Pharmaceuticals at Chiral-Encoded Metal Surfaces.","finding":"","journal":"Chemistry (Weinheim an der Bergstrasse, Germany)","studyType":"Clinical Study"},{"pmid":"35096110","year":"2022","title":"The Study of the Transport Mechanism of Isorhynchophylline in Liver.","finding":"","journal":"Evidence-based complementary and alternative medicine : eCAM","studyType":"Clinical Study"},{"pmid":"32504973","year":"2020","title":"NiO/SWCNTs coupled with an ionic liquid composite for amplified carbon paste electrode; A feasible approach for improving sensing ability of adrenalone and folic acid in dosage form.","finding":"","journal":"Journal of pharmaceutical and biomedical analysis","studyType":"Clinical Study"}],"tags":[{"label":"adrenalone","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"A01AD06","category":"atc"},{"label":"Active","category":"status"},{"label":"Cardiovascular Agents","category":"pharmacology"},{"label":"Coagulants","category":"pharmacology"},{"label":"Hematologic Agents","category":"pharmacology"},{"label":"Hemostatics","category":"pharmacology"},{"label":"Vasoconstrictor Agents","category":"pharmacology"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"adrenon","offLabel":[],"synonyms":["adrenalone","4-Methylaminoacetopyrocatechol","adrenon","adrenone","methaminoacetocatech","stryphnone","stryphnon"],"timeline":[],"brandName":"Adrenon","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"adrenalone","explanation":"Imagine your body's 'fight or flight' response as a car's accelerator pedal. Adrenon is like a key that presses this pedal, causing your heart to beat faster, your blood vessels to constrict, and your body to prepare for action. This response is meant to help you react quickly to emergencies, but it can also have side effects if it's triggered unnecessarily.","oneSentence":"Adrenon works by stimulating the body's 'fight or flight' response, mimicking the effects of epinephrine.","technicalDetail":"Adrenon exerts its effects by binding to adrenergic receptors, specifically alpha and beta-adrenergic receptors, which triggers a cascade of downstream signaling events that ultimately lead to increased sympathetic nervous system activity."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/96","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ADRENALONE","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:29:16.558433","biosimilars":[],"competitors":[{"drugName":"epinephrine","drugSlug":"epinephrine","fdaApproval":"1948-11-19","patentExpiry":"Oct 20, 2036","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"acetylsalicylic acid","drugSlug":"acetylsalicylic-acid","fdaApproval":"1950-04-12","relationship":"same-class"},{"drugName":"amlexanox","drugSlug":"amlexanox","fdaApproval":"1996-12-17","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"becaplermin","drugSlug":"becaplermin","fdaApproval":"1997-12-16","relationship":"same-class"}],"genericName":"adrenalone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"epinephrine","brandName":"epinephrine","genericName":"epinephrine","approvalYear":"1948","relationship":"same-class"},{"drugId":"acetylsalicylic-acid","brandName":"acetylsalicylic acid","genericName":"acetylsalicylic acid","approvalYear":"1950","relationship":"same-class"},{"drugId":"amlexanox","brandName":"amlexanox","genericName":"amlexanox","approvalYear":"1996","relationship":"same-class"},{"drugId":"becaplermin","brandName":"becaplermin","genericName":"becaplermin","approvalYear":"1997","relationship":"same-class"}],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"NDDF":"005666","UNII":"EGU41QL329","CHEBI":"CHEBI:134821","INN_ID":"3174","RXNORM":"17073","UMLSCUI":"C0050876","ChEMBL_ID":"CHEMBL2103996","KEGG_DRUG":"D02774","DRUGBANK_ID":"DB13394","PUBCHEM_CID":"7436","MESH_SUPPLEMENTAL_RECORD_UI":"C040224"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":22,"therapeuticAreas":["Nephrology"],"atcClassification":{"source":"DrugCentral","atcCode":"A01AD06","allCodes":["A01AD06","B02BC05"]},"biosimilarFilings":[],"recentPublications":[{"date":"2026 Jan","pmid":"40876091","title":"Hydrogel-based drug delivery system designed for chemotherapy-induced alopecia.","journal":"Biomaterials advances"},{"date":"2024 Aug 30","pmid":"39229547","title":"Study on the uptake of Gastrodin in the liver.","journal":"Heliyon"},{"date":"2023 Nov 2","pmid":"37857579","title":"Highly Enantioselective Synthesis of Pharmaceuticals at Chiral-Encoded Metal Surfaces.","journal":"Chemistry (Weinheim an der Bergstrasse, Germany)"},{"date":"2022","pmid":"35096110","title":"The Study of the Transport Mechanism of Isorhynchophylline in Liver.","journal":"Evidence-based complementary and alternative medicine : eCAM"},{"date":"2020 Sep 5","pmid":"32504973","title":"NiO/SWCNTs coupled with an ionic liquid composite for amplified carbon paste electrode; A feasible approach for improving sensing ability of adrenalone and folic acid in dosage form.","journal":"Journal of pharmaceutical and biomedical analysis"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Adrenon (ADRENALONE) is a small molecule adrenalone, a synthetic analogue of epinephrine. Its exact target is unknown, but it is believed to work by stimulating the body's 'fight or flight' response. Adrenon is not FDA approved for any indications, and its commercial status, patent status, and availability of generic manufacturers are also unknown. As a result, key safety considerations and pharmacokinetic properties, such as half-life and bioavailability, are also not well established. Further research is needed to fully understand Adrenon's mechanism of action and clinical utility.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}