{"id":"adjuvanted-hep-b-vaccine-lot-3","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site pain or erythema"},{"rate":null,"effect":"Fatigue"},{"rate":null,"effect":"Myalgia"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Low-grade fever"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The vaccine contains hepatitis B surface antigen (HBsAg) combined with an adjuvant that enhances the immunogenicity of the antigen. The adjuvant amplifies the body's innate immune response, leading to stronger and more durable antibody production and T-cell activation against HBsAg. This provides protection against hepatitis B virus infection.","oneSentence":"This adjuvanted hepatitis B vaccine stimulates the immune system to produce antibodies and cellular immunity against hepatitis B virus surface antigen.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:59:55.543Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of hepatitis B infection"}]},"trialDetails":[{"nctId":"NCT00480116","phase":"PHASE3","title":"Consistency Study of Three Lots of Henogen's Adjuvanted Hepatitis B Vaccine When Given in 0, 1 Month Schedule","status":"COMPLETED","sponsor":"Henogen","startDate":"2008-01","conditions":"Hepatitis B","enrollment":450}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Adjuvanted Hep B vaccine Lot 3","genericName":"Adjuvanted Hep B vaccine Lot 3","companyName":"Henogen","companyId":"henogen","modality":"Biologic","firstApprovalDate":"","aiSummary":"This adjuvanted hepatitis B vaccine stimulates the immune system to produce antibodies and cellular immunity against hepatitis B virus surface antigen. Used for Prevention of hepatitis B infection.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}