{"id":"ad-337","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Headache"},{"rate":"5-10%","effect":"Nausea"},{"rate":"5-10%","effect":"Diarrhea"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"S1P1 is a sphingosine-1-phosphate receptor involved in lymphocyte trafficking and immune response. By targeting this receptor, AD 337 aims to modulate immune cell activity and potentially treat autoimmune diseases.","oneSentence":"AD 337 is a small molecule targeting the S1P1 receptor.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T03:19:11.728Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Relapsing multiple sclerosis"}]},"trialDetails":[{"nctId":"NCT00310817","phase":"PHASE2","title":"Safety and Immunogenicity of Novartis Meningococcal ACWY Conjugate Vaccine in Healthy Children Aged 12-59 Months.","status":"COMPLETED","sponsor":"Novartis Vaccines","startDate":"2005-03","conditions":"Meningococcal Meningitis","enrollment":623},{"nctId":"NCT00377039","phase":"PHASE2","title":"A Multicentre Trial to Determine the Efficacy and Safety of AD-337 in the Treatment of Fibromyalgia","status":"COMPLETED","sponsor":"Sosei","startDate":"2006-08","conditions":"Fibromyalgia","enrollment":100}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":1341,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"AD 337","genericName":"AD 337","companyName":"Sosei","companyId":"sosei","modality":"Small molecule","firstApprovalDate":"","aiSummary":"AD 337 is a small molecule targeting the S1P1 receptor. Used for Relapsing multiple sclerosis.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}