{"id":"acyc-vehicle","safety":{"commonSideEffects":[{"rate":null,"effect":"Local irritation or burning at application site"},{"rate":null,"effect":"Erythema"},{"rate":null,"effect":"Pruritus"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"ACYC vehicle represents a pharmaceutical formulation technology that improves the penetration and bioavailability of acyclovir at the site of application. By optimizing the vehicle or carrier system, this formulation aims to increase therapeutic efficacy while potentially reducing systemic exposure and adverse effects associated with traditional acyclovir delivery.","oneSentence":"ACYC vehicle is a topical formulation designed to enhance the delivery and efficacy of acyclovir for localized antiviral treatment.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:44:37.979Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Herpes simplex virus infections (topical indication, likely cold sores or genital herpes)"}]},"trialDetails":[{"nctId":"NCT01701024","phase":"PHASE3","title":"Clinical Study to Test the Efficacy and Safety of ACYC to Treat Moderate to Severe Acne","status":"COMPLETED","sponsor":"Bausch Health Americas, Inc.","startDate":"2012-10","conditions":"Acne","enrollment":498}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"ACYC vehicle","genericName":"ACYC vehicle","companyName":"Bausch Health Americas, Inc.","companyId":"bausch-health-americas-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ACYC vehicle is a control treatment used in clinical studies to compare the efficacy and safety of ACYC in treating moderate to severe acne. The exact mechanism of ACYC is unknown, as it is not specified in available databases.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}