{"id":"activa-kids-bioactive-restorative-material","safety":{"commonSideEffects":[]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This material is designed to release bioactive ions and stimulate the formation of mineralized tissue, supporting the natural healing and restoration of tooth structure in children. It combines calcium, phosphate, and other bioactive components to enhance dentin remineralization and provide a biocompatible interface between the restoration and tooth tissue.","oneSentence":"ACTIVA KIDS is a bioactive restorative material that promotes remineralization and biocompatibility in pediatric dental applications.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:44:09.145Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Pediatric dental caries restoration"},{"name":"Dentin remineralization in primary and permanent teeth"}]},"trialDetails":[{"nctId":"NCT03788616","phase":"PHASE3","title":"Fluoride Release,Compressive Strength and Clinical Performance of a Bioactive Restorative Material in ART","status":"COMPLETED","sponsor":"Marina F Fahmy, MD","startDate":"2018-11-17","conditions":"Dental Caries","enrollment":110}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["ACTIVA , Modified composite"],"phase":"phase_3","status":"active","brandName":"ACTIVA KIDS bioactive restorative material","genericName":"ACTIVA KIDS bioactive restorative material","companyName":"Marina F Fahmy, MD","companyId":"marina-f-fahmy-md","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ACTIVA KIDS is a bioactive restorative material that promotes remineralization and biocompatibility in pediatric dental applications. Used for Pediatric dental caries restoration, Dentin remineralization in primary and permanent teeth.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}