{"id":"actidose-aqua","safety":{"commonSideEffects":[{"rate":null,"effect":"Black discoloration of stool"},{"rate":null,"effect":"Constipation"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Vomiting"},{"rate":null,"effect":"Abdominal discomfort"}]},"_chembl":null,"_dailymed":{"setId":"c85dc235-3f42-4361-9bd2-1aaff798ad75","title":"ACTIDOSE AQUA (ACTIVATED CHARCOAL) SUSPENSION [PADAGIS US LLC]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Activated charcoal is a highly porous form of carbon with a large surface area that adsorbs (binds) various drugs, toxins, and poisons within the stomach and intestines. By binding these substances, it prevents their systemic absorption and facilitates their elimination through feces. This mechanism makes it useful as a general antidote in acute poisoning and overdose situations.","oneSentence":"Actidose Aqua is an aqueous suspension of activated charcoal that binds toxins and drugs in the gastrointestinal tract to prevent their absorption.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T02:20:42.264Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acute poisoning and overdose (general antidote for various drugs and toxins)"},{"name":"Gastrointestinal decontamination in emergency settings"}]},"trialDetails":[{"nctId":"NCT01955382","phase":"PHASE2","title":"Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With Malaria","status":"COMPLETED","sponsor":"National Institute of Allergy and Infectious Diseases (NIAID)","startDate":"2013-09","conditions":"Malaria, Severe Malaria","enrollment":70}],"_emaApprovals":[],"_faersSignals":[{"count":1,"reaction":"ACCIDENTAL EXPOSURE"},{"count":1,"reaction":"AGITATION"},{"count":1,"reaction":"BLOOD GLUCOSE INCREASED"},{"count":1,"reaction":"DROOLING"},{"count":1,"reaction":"EYE ROLLING"},{"count":1,"reaction":"LIP SWELLING"},{"count":1,"reaction":"MIOSIS"},{"count":1,"reaction":"MOOD ALTERED"},{"count":1,"reaction":"SOMNOLENCE"}],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Oral activated charcoal"],"phase":"marketed","status":"active","brandName":"Actidose Aqua","genericName":"Actidose Aqua","companyName":"National Institute of Allergy and Infectious Diseases (NIAID)","companyId":"national-institute-of-allergy-and-infectious-diseases-niaid","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Actidose Aqua is an aqueous suspension of activated charcoal that binds toxins and drugs in the gastrointestinal tract to prevent their absorption. Used for Acute poisoning and overdose (general antidote for various drugs and toxins), Gastrointestinal decontamination in emergency settings.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}