{"id":"acthib-dpt-takeda","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site reactions (pain, redness, swelling)"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Irritability"},{"rate":null,"effect":"Drowsiness"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This is a multi-component vaccine combining the ActHIB conjugate vaccine (against Haemophilus influenzae type b) with DPT (diphtheria, pertussis, tetanus) components. It works by stimulating the immune system to produce antibodies and cellular immunity against these bacterial pathogens, providing protection against invasive Hib disease and the three DPT diseases. The conjugate technology enhances immunogenicity in infants and young children.","oneSentence":"ActHIB+ DPT-TAKEDA is a combined vaccine that provides immunization against Haemophilus influenzae type b, diphtheria, pertussis, and tetanus through active immunization.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:44:09.001Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Active immunization against Haemophilus influenzae type b, diphtheria, pertussis, and tetanus in infants and children"}]},"trialDetails":[{"nctId":"NCT01379846","phase":"PHASE3","title":"Study of TAK-816 in Healthy Infants","status":"COMPLETED","sponsor":"Takeda","startDate":"2011-06","conditions":"Immunization","enrollment":416}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Haemophilus b Conjugate Vaccine (Tetanus Toxoid Conjugate)"],"phase":"phase_3","status":"active","brandName":"ActHIB+ DPT-TAKEDA","genericName":"ActHIB+ DPT-TAKEDA","companyName":"Takeda","companyId":"takeda","modality":"Biologic","firstApprovalDate":"","aiSummary":"ActHIB+ DPT-TAKEDA is a combined vaccine that provides immunization against Haemophilus influenzae type b, diphtheria, pertussis, and tetanus through active immunization. Used for Active immunization against Haemophilus influenzae type b, diphtheria, pertussis, and tetanus in infants and children.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}