{"id":"aconite-pain-oil","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation or contact dermatitis"},{"rate":null,"effect":"Local burning or tingling sensation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Aconite (monkshood) contains bioactive alkaloids that are traditionally used in herbal medicine to modulate pain signaling and reduce inflammation when applied topically. The oil formulation allows transdermal delivery of these compounds to affected tissues, where they may interact with pain receptors and inflammatory pathways to provide symptomatic relief.","oneSentence":"Aconite pain oil is a topical herbal preparation that delivers alkaloid compounds from aconite root to provide local analgesic and anti-inflammatory effects for pain relief.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:59:02.035Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Localized pain relief (musculoskeletal pain, joint pain, rheumatic conditions)"}]},"trialDetails":[{"nctId":"NCT06186479","phase":"PHASE3","title":"Clinical Trial With Aconite Pain Oil in Oncology Patients Under Chemotherapy to Prevent CIPN Grade-II, to Reduce Symptoms and to Improve the Quality of Life of Patients With CIPN","status":"RECRUITING","sponsor":"WALA Heilmittel GmbH","startDate":"2024-03-13","conditions":"Chemotherapy-induced Polyneuropathy","enrollment":350}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":5,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Aconite pain oil","genericName":"Aconite pain oil","companyName":"WALA Heilmittel GmbH","companyId":"wala-heilmittel-gmbh","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Aconite pain oil is a topical herbal preparation that delivers alkaloid compounds from aconite root to provide local analgesic and anti-inflammatory effects for pain relief. Used for Localized pain relief (musculoskeletal pain, joint pain, rheumatic conditions).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}