{"id":"acid-mycophenolic-myfortic","safety":{"commonSideEffects":[{"rate":"10-20%","effect":"Diarrhea"},{"rate":"10-20%","effect":"Nausea"},{"rate":"5-10%","effect":"Vomiting"},{"rate":"5-10%","effect":"Abdominal pain"},{"rate":"5-10%","effect":"Headache"},{"rate":"5-10%","effect":"Fatigue"},{"rate":"5-10%","effect":"Infection"},{"rate":"5-10%","effect":"Anemia"},{"rate":"5-10%","effect":"Leukopenia"},{"rate":"5-10%","effect":"Thrombocytopenia"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"By inhibiting IMPDH, acid mycophenolic reduces the proliferation of T and B lymphocytes, which are key components of the immune system. This action is particularly beneficial in preventing organ rejection in transplant patients. Additionally, the inhibition of IMPDH can also affect the function of other cells, such as dendritic cells and natural killer cells, which play a role in the immune response.","oneSentence":"Acid mycophenolic inhibits inosine monophosphate dehydrogenase (IMPDH), an enzyme involved in the de novo synthesis of guanosine nucleotides.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:59:01.251Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of organ rejection in kidney transplant patients"}]},"trialDetails":[{"nctId":"NCT03844061","phase":"PHASE2","title":"Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis","status":"RECRUITING","sponsor":"Hospital for Special Surgery, New York","startDate":"2019-07-29","conditions":"Systemic Sclerosis","enrollment":30},{"nctId":"NCT01659606","phase":"PHASE2","title":"Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With 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