{"id":"acetylpheneturide","rwe":[{"pmid":"7205534","year":"1980","title":"Differential antagonisms of anticonvulsants to various components of maximal seizures induced by electroshock or pentylenetetrazol in mice.","finding":"","journal":"Journal of pharmacobio-dynamics","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"},{"label":"Epilepsy","category":"indication"}],"phase":"unknown","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"crampol","offLabel":[],"synonyms":["crampol","acetylpheneturide","(+/-)-Acetylpheneturide","P-3981"],"timeline":[],"brandName":"Crampol","ecosystem":[{"indication":"Epilepsy","otherDrugs":[{"name":"amobarbital","slug":"amobarbital","company":""},{"name":"carbamazepine","slug":"carbamazepine","company":"Novartis"},{"name":"diazepam","slug":"diazepam","company":"Roche"},{"name":"felbamate","slug":"felbamate","company":"Meda Pharms"}],"globalPrevalence":50000000}],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your brain is a busy city with many different neighborhoods. Crampol helps calm down the activity in the neighborhoods where seizures occur, making it less likely for them to happen. This is done by affecting the way neurons communicate with each other.","oneSentence":"Crampol works by modulating neuronal activity to reduce seizure frequency.","technicalDetail":"Crampol is a small molecule that interacts with unknown targets to modulate neuronal excitability and reduce seizure activity."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/72","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=acetylpheneturide","fields":["publications"],"source":"PubMed/NCBI"}],"_enrichedAt":"2026-03-30T08:24:15.894777","biosimilars":[],"competitors":[],"genericName":"acetylpheneturide","indications":{"approved":[{"name":"Epilepsy","source":"DrugCentral","snomedId":84757009,"regulator":"FDA","usPrevalence":3400000,"globalPrevalence":50000000,"prevalenceMethod":"curated","prevalenceSource":"WHO, 2023"}],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"G083008IJ0","CHEBI":"CHEBI:31166","ChEMBL_ID":"CHEMBL2107062","KEGG_DRUG":"D01409","PUBCHEM_CID":"1999"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Neuroscience"],"biosimilarFilings":[],"recentPublications":[{"date":"1980 Oct","pmid":"7205534","title":"Differential antagonisms of anticonvulsants to various components of maximal seizures induced by electroshock or pentylenetetrazol in mice.","journal":"Journal of pharmacobio-dynamics"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Crampol (acetylpheneturide) is a small molecule modality developed for the treatment of epilepsy. Its exact mechanism of action and target are unknown, but it is believed to work by modulating neuronal activity. Crampol is used to manage seizures in patients with epilepsy, but its commercial status and safety considerations are not well-documented. Further research is needed to fully understand its pharmacological properties and potential risks. As a result, its use should be approached with caution and under the guidance of a qualified healthcare professional.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":false,"score":2}}