{"id":"acetaminophen-tablets","safety":{"commonSideEffects":[{"rate":null,"effect":"Hepatotoxicity (at overdose)"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Rash"}]},"_chembl":null,"_dailymed":{"setId":"2a31a975-72f9-2a16-e063-6394a90a8149","title":"ACETAMINOPHEN 250 MG AND IBUPROFEN 125 MG (ACETAMINOPHEN 250 MG AND IBUPROFEN 125 MG TABLETS) TABLET [SUN PHARMACEUTICAL INDUSTRIES, INC.]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Acetaminophen is believed to work primarily through inhibition of cyclooxygenase (COX) enzymes in the brain and spinal cord, reducing prostaglandin production and thereby lowering the pain threshold and resetting the hypothalamic thermoregulatory set point. Unlike NSAIDs, it has minimal peripheral anti-inflammatory effects and does not significantly inhibit COX in peripheral tissues.","oneSentence":"Acetaminophen reduces pain and fever by inhibiting prostaglandin synthesis in the central nervous system.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T02:20:36.708Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Mild to moderate pain"},{"name":"Fever reduction"}]},"trialDetails":[{"nctId":"NCT06966700","phase":"PHASE3","title":"A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)","status":"RECRUITING","sponsor":"Merck Sharp & Dohme LLC","startDate":"2025-06-30","conditions":"Breast Neoplasms, Triple Negative Breast Neoplasms, HR Low-Positive/HER2-Negative Breast Neoplasms","enrollment":2400},{"nctId":"NCT07458282","phase":"NA","title":"The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving 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