{"id":"aceglatone","rwe":[{"pmid":"21479479","year":"2008","title":"Effects of synthetic and natural in vivo inhibitors of β-glucuronidase on azoxymethane-induced colon carcinogenesis in rats.","finding":"","journal":"Molecular medicine reports","studyType":"Clinical Study"}],"tags":[{"label":"Small Molecule","category":"modality"},{"label":"Active","category":"status"}],"phase":"phase_2","safety":{"commonSideEffects":[]},"trials":[],"aliases":[],"patents":[],"pricing":[],"allNames":"glucaron","offLabel":[],"synonyms":["aceglatone","glucaron"],"timeline":[],"brandName":"Glucaron","ecosystem":[],"mechanism":{"modality":"Small Molecule","explanation":"Imagine your body's cells are like a orchestra, and each cell has its own specific role to play. Glucaron is like a conductor that helps the cells work together in harmony, but we don't yet know exactly how it does this. By understanding how Glucaron interacts with the cells, we can learn more about how it might help treat certain diseases.","oneSentence":"Glucaron works by binding to and modulating specific biological targets, although the exact mechanism is not yet fully understood.","technicalDetail":"Glucaron's mechanism of action is likely to involve the inhibition or activation of specific enzymes or receptors, although the precise molecular details are not yet publicly disclosed."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/Aceglatone","title":"Aceglatone","extract":"Aceglatone (Glucaron) is an antineoplastic drug available in Japan."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/45","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=ACEGLATONE","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/Aceglatone","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T08:21:53.527847","biosimilars":[],"competitors":[],"genericName":"aceglatone","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[],"trialDetails":[],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"crossReferences":{"UNII":"347Q3OOJ13","CHEBI":"CHEBI:31160","INN_ID":"3151","UMLSCUI":"C0050406","ChEMBL_ID":"CHEMBL446209","KEGG_DRUG":"D01805","PUBCHEM_CID":"636372","MESH_SUPPLEMENTAL_RECORD_UI":"C038936"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":1,"therapeuticAreas":["Other"],"biosimilarFilings":[],"recentPublications":[{"date":"2008 Sep-Oct","pmid":"21479479","title":"Effects of synthetic and natural in vivo inhibitors of β-glucuronidase on azoxymethane-induced colon carcinogenesis in rats.","journal":"Molecular medicine reports"}],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Glucaron is a small molecule with synonyms including ACEGLATONA, ACEGLATONE, and GLUCARON.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":false,"score":1}}