{"id":"acacia-catechu","safety":{"commonSideEffects":[{"rate":null,"effect":"Tooth staining"},{"rate":null,"effect":"Oral irritation"}]},"_chembl":{"chemblId":"CHEMBL2108172","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Acacia catechu (also known as cutch or catechu) is a plant extract rich in polyphenols, particularly catechins and tannins, which exert antimicrobial activity against oral pathogens and provide astringent properties that help reduce inflammation and bleeding in oral tissues. These compounds have been traditionally used in dental and oral care formulations to support gum health and reduce bacterial colonization.","oneSentence":"Acacia catechu extract provides antimicrobial, astringent, and anti-inflammatory effects through its tannin and catechin content.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:26:29.991Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Oral health support and gum disease management"},{"name":"Antimicrobial oral rinse or dental formulation"}]},"trialDetails":[{"nctId":"NCT06805292","phase":"NA","title":"Evaluation of Acacia Catechu and Low-Level Laser in the Treatmentof Stage II Periodontitis","status":"COMPLETED","sponsor":"Faculty of Dental Medicine for Girls","startDate":"2022-09-20","conditions":"Chronic Periodontitis","enrollment":60},{"nctId":"NCT05994391","phase":"NA","title":"A Prospective, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of LasoperinTM on Cognitive Function in Healthy Adults","status":"COMPLETED","sponsor":"Lindenwood University","startDate":"2022-06-03","conditions":"Cognitive Impairment, Cognitive Decline, Cognition Disorders in Old Age","enrollment":100},{"nctId":"NCT02154594","phase":"PHASE4","title":"\"The Efficacy of Acacia Catechu Mouthrinse as Antiplaque and Antigingivitis Agent in Fixed Orthodontic Appliance Patients.","status":"COMPLETED","sponsor":"Tatyasaheb Kore Dental College","startDate":"2014-02","conditions":"Gingivitis","enrollment":60}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":158,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Acacia catechu","genericName":"Acacia catechu","companyName":"Tatyasaheb Kore Dental College","companyId":"tatyasaheb-kore-dental-college","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Acacia catechu extract provides antimicrobial, astringent, and anti-inflammatory effects through its high tannin and catechin content. Used for Oral health maintenance and dental care (likely used in dental formulations by Tatyasaheb Kore Dental College).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}