{"id":"a197-ophthalmic-solution","safety":{"commonSideEffects":[{"rate":"5-10%","effect":"Eye irritation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"A197 Ophthalmic Solution works by inhibiting the production of inflammatory mediators in the eye, thereby reducing swelling and pain. This is achieved through the action of its active ingredient, which is a corticosteroid. Corticosteroids are a class of steroid hormones that are produced by the adrenal gland and play a crucial role in regulating inflammation in the body.","oneSentence":"A197 Ophthalmic Solution is a topical corticosteroid used to reduce inflammation in the eye.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T02:28:06.395Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Treatment of inflammation and pain in the eye"}]},"trialDetails":[{"nctId":"NCT05238597","phase":"PHASE2","title":"A Study to Evaluate the Safety, Tolerability, and Efficacy of A197 in Subjects With Dry Eye Disease","status":"COMPLETED","sponsor":"Aramis Biosciences, Inc.","startDate":"2022-01-25","conditions":"Dry Eye Disease","enrollment":207}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_2","status":"active","brandName":"A197 Ophthalmic Solution","genericName":"A197 Ophthalmic Solution","companyName":"Aramis Biosciences, Inc.","companyId":"aramis-biosciences-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A197 Ophthalmic Solution is a topical corticosteroid used to reduce inflammation in the eye. Used for Treatment of inflammation and pain in the eye.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}