{"id":"a-arm-da-90","safety":{"commonSideEffects":[{"rate":"50-70%","effect":"Neutropenia"},{"rate":"30-50%","effect":"Anemia"},{"rate":"20-40%","effect":"Thrombocytopenia"}]},"_chembl":{"chemblId":"CHEMBL498283","moleculeType":"Small molecule","molecularWeight":"405.63"},"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"DA-90 works by binding to CD19 on the surface of B cells, marking them for destruction by the immune system. This leads to the depletion of cancerous B cells in the body.","oneSentence":"DA-90 is a monoclonal antibody targeting CD19.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:58:23.271Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Relapsed or refractory B-cell acute lymphoblastic leukemia"}]},"trialDetails":[{"nctId":"NCT03257241","phase":"PHASE3","title":"A PALG Prospective Multicenter Clinical Trial to Compare the Efficacy of Two Standard Induction Therapies (DA-90 vs DAC) and Two Standard Salvage Regimens (FLAG-IDA vs CLAG-M) in AML Patients ≤ 60 Years Old","status":"UNKNOWN","sponsor":"Polish Adult Leukemia Group","startDate":"2017-07-03","conditions":"Acute Myeloid Leukemia","enrollment":582}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Daunorubicin, Cytarabine"],"phase":"phase_3","status":"active","brandName":"A arm (DA-90)","genericName":"A arm (DA-90)","companyName":"Polish Adult Leukemia Group","companyId":"polish-adult-leukemia-group","modality":"Small molecule","firstApprovalDate":"","aiSummary":"DA-90 is a monoclonal antibody targeting CD19. Used for Relapsed or refractory B-cell acute lymphoblastic leukemia.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}