{"id":"4-dimethylaminophenol","rwe":[],"tags":[{"label":"4-dimethylaminophenol","category":"class"},{"label":"Small Molecule","category":"modality"},{"label":"V03AB27","category":"atc"},{"label":"Active","category":"status"},{"label":"Antidotes","category":"pharmacology"},{"label":"Protective Agents","category":"pharmacology"}],"phase":"unknown","safety":{"commonSideEffects":[]},"trials":["NCT04164667","NCT00033644"],"aliases":[],"patents":[],"pricing":[],"allNames":"dmap","offLabel":[],"synonyms":["4-dimethylaminophenol","DMAP","N,N-Dimethyl-4-aminophenol"],"timeline":[],"brandName":"Dmap","ecosystem":[],"mechanism":{"modality":"Small Molecule","drugClass":"4-dimethylaminophenol","explanation":"Imagine Dmap as a key that unlocks a specific lock in the body, allowing it to work properly. However, the exact lock and how Dmap interacts with it are still being studied. This process may help to treat certain conditions, but more research is needed to confirm its effectiveness and safety.","oneSentence":"Dmap is thought to work by modulating a specific biological pathway, although the exact mechanism is not well understood.","technicalDetail":"Dmap is a small molecule that likely interacts with a specific protein or receptor, altering its activity and leading to a therapeutic effect. However, the precise molecular details of this interaction are currently unknown."},"_wikipedia":{"url":"https://en.wikipedia.org/wiki/4-Dimethylaminophenol","title":"4-Dimethylaminophenol","extract":"4-Dimethylaminophenol (DMAP) is an aromatic compound containing both phenol and amine functional groups. It has the molecular formula C8H11NO."},"commercial":{},"references":[{"id":1,"url":"https://drugcentral.org/drugcard/4312","fields":["approvals","synonyms","ATC","PK","indications","contraindications","DDIs","targets","patents","FAERS"],"source":"DrugCentral"},{"id":2,"url":"https://pubmed.ncbi.nlm.nih.gov/?term=4-dimethylaminophenol","fields":["publications"],"source":"PubMed/NCBI"},{"id":3,"url":"https://en.wikipedia.org/wiki/4-Dimethylaminophenol","fields":["history","overview"],"source":"Wikipedia"}],"_enrichedAt":"2026-03-30T07:24:16.665424","biosimilars":[],"competitors":[{"drugName":"nalorphine","drugSlug":"nalorphine","fdaApproval":"","relationship":"same-class"},{"drugName":"pralidoxime","drugSlug":"pralidoxime","fdaApproval":"1964-03-11","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"prednisolone","drugSlug":"prednisolone","fdaApproval":"1955-06-21","genericCount":42,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"promethazine","drugSlug":"promethazine","fdaApproval":"1951-03-29","genericCount":48,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"sodium nitrite","drugSlug":"sodium-nitrite","fdaApproval":"2011-01-14","patentExpiry":"Feb 10, 2030","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"dimercaprol","drugSlug":"dimercaprol","fdaApproval":"1946-05-06","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"protamine sulfate","drugSlug":"protamine-sulfate","fdaApproval":"1969-08-13","genericCount":2,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"naloxone","drugSlug":"naloxone","fdaApproval":"1971-04-13","patentExpiry":"Oct 30, 2028","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"ethanol","drugSlug":"ethanol","fdaApproval":"1946-01-17","patentStatus":"Unknown","relationship":"same-class"},{"drugName":"methylthioninium chloride","drugSlug":"methylthioninium-chloride","fdaApproval":"","relationship":"same-class"},{"drugName":"copper sulfate","drugSlug":"copper-sulfate","fdaApproval":"1987-05-05","relationship":"same-class"},{"drugName":"potassium iodide","drugSlug":"potassium-iodide","fdaApproval":"1979-11-09","genericCount":3,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"amyl nitrite","drugSlug":"amyl-nitrite","fdaApproval":"","relationship":"same-class"},{"drugName":"acetylcysteine","drugSlug":"acetylcysteine","fdaApproval":"1963-09-14","patentExpiry":"May 8, 2032","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"flumazenil","drugSlug":"flumazenil","fdaApproval":"1991-12-20","genericCount":8,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"methionine","drugSlug":"methionine","fdaApproval":"","relationship":"same-class"},{"drugName":"prussian blue","drugSlug":"prussian-blue","fdaApproval":"2003-10-02","relationship":"same-class"},{"drugName":"hydroxocobalamin","drugSlug":"hydroxocobalamin","fdaApproval":"1978-08-16","genericCount":5,"patentStatus":"Off-patent — generic available","relationship":"same-class"},{"drugName":"fomepizole","drugSlug":"fomepizole","fdaApproval":"1997-12-04","patentExpiry":"Jun 30, 2027","patentStatus":"Patent protected","relationship":"same-class"},{"drugName":"sugammadex","drugSlug":"sugammadex","fdaApproval":"2015-12-15","patentExpiry":"Jul 27, 2026","patentStatus":"Patent protected","relationship":"same-class"}],"dataSources":[{"url":"https://clinicaltrials.gov","name":"ClinicalTrials.gov","fields":["trialDetails","trials"],"retrievedDate":"2026-04-07"},{"url":"https://drugcentral.org","name":"DrugCentral","fields":["indications","contraindications","safety","target","drugInteractions"],"retrievedDate":"2026-04-07"}],"genericName":"4-dimethylaminophenol","indications":{"approved":[],"offLabel":[],"pipeline":[]},"drugCategory":"active","labelChanges":[],"relatedDrugs":[{"drugId":"nalorphine","brandName":"nalorphine","genericName":"nalorphine","approvalYear":"","relationship":"same-class"},{"drugId":"pralidoxime","brandName":"pralidoxime","genericName":"pralidoxime","approvalYear":"1964","relationship":"same-class"},{"drugId":"prednisolone","brandName":"prednisolone","genericName":"prednisolone","approvalYear":"1955","relationship":"same-class"},{"drugId":"promethazine","brandName":"promethazine","genericName":"promethazine","approvalYear":"1951","relationship":"same-class"},{"drugId":"sodium-nitrite","brandName":"sodium nitrite","genericName":"sodium nitrite","approvalYear":"2011","relationship":"same-class"},{"drugId":"dimercaprol","brandName":"dimercaprol","genericName":"dimercaprol","approvalYear":"1946","relationship":"same-class"},{"drugId":"protamine-sulfate","brandName":"protamine sulfate","genericName":"protamine sulfate","approvalYear":"1969","relationship":"same-class"},{"drugId":"naloxone","brandName":"naloxone","genericName":"naloxone","approvalYear":"1971","relationship":"same-class"},{"drugId":"ethanol","brandName":"ethanol","genericName":"ethanol","approvalYear":"1946","relationship":"same-class"},{"drugId":"methylthioninium-chloride","brandName":"methylthioninium chloride","genericName":"methylthioninium chloride","approvalYear":"","relationship":"same-class"}],"trialDetails":[{"nctId":"NCT04164667","phase":"NA","title":"Enhancing Executive Function and Self-regulation Success Through the Promotion of Brain Health Behaviors: a Telehealth Pilot Study for Veterans with Chronic Multi-symptom Illness.","status":"COMPLETED","sponsor":"War Related Illness and Injury Study Center","isPivotal":false,"enrollment":24,"indication":"Chronic Multisymptom Illness","completionDate":"2021-07-06"},{"nctId":"NCT00033644","phase":"Phase 2","title":"A Phase II Evaluation of DMAP Plus GM-CSF in the Treatment of Advanced, Persistent, or Recurrent Leiomyosarcoma of the Uterus","status":"TERMINATED","sponsor":"Gynecologic Oncology Group","isPivotal":false,"enrollment":0,"indication":"Sarcoma","completionDate":""}],"genericFilers":[],"latestUpdates":[],"manufacturing":[],"administration":{},"crossReferences":{"NDDF":"007209","UNII":"X387L5559O","CHEBI":"CHEBI:135941","RXNORM":"15027","UMLSCUI":"C0048250","ChEMBL_ID":"CHEMBL3707216","DRUGBANK_ID":"DB13549","PUBCHEM_CID":"22174","MESH_SUPPLEMENTAL_RECORD_UI":"C020292"},"formularyStatus":[],"_enricherVersion":"v2","developmentCodes":[],"ownershipHistory":[],"publicationCount":67,"therapeuticAreas":["Other"],"atcClassification":{"source":"DrugCentral","atcCode":"V03AB27","allCodes":["V03AB27"]},"biosimilarFilings":[],"recentPublications":[],"companionDiagnostics":[],"genericManufacturerList":[],"status":"active","companyName":"","companyId":"unknown","modality":"Small Molecule","firstApprovalDate":"","aiSummary":"Dmap (4-dimethylaminophenol) is a small molecule drug of the 4-dimethylaminophenol class, but information on its target, approved indications, and commercial status is currently unavailable. As a result, its clinical use, safety profile, and pharmacokinetic properties remain unknown. Further research is necessary to determine the efficacy and potential risks associated with Dmap. The development and ownership of Dmap are also unclear. More information is needed to assess its potential as a therapeutic agent.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"partial","dataCompleteness":{"mechanism":true,"indications":false,"safety":false,"trials":true,"score":2}}