{"id":"10rac-acetylcystein","safety":{"commonSideEffects":[{"rate":null,"effect":"Injection site reactions"},{"rate":null,"effect":"Fever"},{"rate":null,"effect":"Fatigue"}]},"_chembl":{"chemblId":"CHEMBL3706516","moleculeType":"Small molecule","molecularWeight":"303.38"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"10RAC is a dendritic cell-based immunotherapy that activates the immune system against cancer cells, while acetylcysteine serves as a free radical scavenger and mucolytic agent that may reduce oxidative stress and support immune function. The combination is designed to enhance anti-tumor immunity while mitigating oxidative damage.","oneSentence":"10RAC combined with acetylcysteine works through immunotherapy (10RAC) paired with an antioxidant/mucolytic agent to enhance immune response and reduce oxidative stress.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:24:26.940Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Advanced or metastatic cancer (specific indications not clearly defined in available literature)"}]},"trialDetails":[{"nctId":"NCT01572597","phase":"PHASE4","title":"Increased Re-eradication Rate of Helicobacter Pylori by Adding N-acetylcystein or Metronidazole to the Triple Therapy","status":"UNKNOWN","sponsor":"Buddhist Tzu Chi General Hospital","startDate":"2011-06","conditions":"Bacterial Infection Due to Helicobacter Pylori (H. Pylori)","enrollment":120}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Pariet","Klaricid","Hiconcil","Fluimucil"],"phase":"marketed","status":"active","brandName":"10RAC+acetylcystein","genericName":"10RAC+acetylcystein","companyName":"Buddhist Tzu Chi General Hospital","companyId":"buddhist-tzu-chi-general-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"10RAC+acetylcystein is a small molecule intervention that has been studied as a treatment for bacterial infections caused by Helicobacter Pylori. It is part of a second-line eradication regimen for H. Pylori, which aims to increase the re-eradication rate of the bacteria.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}