{"id":"1-3-1-6-d-glucan","safety":{"commonSideEffects":[{"rate":null,"effect":"Mild gastrointestinal disturbance"},{"rate":null,"effect":"Fever or chills"},{"rate":null,"effect":"Allergic reactions"}]},"_chembl":{"chemblId":"CHEMBL229282","moleculeType":"Small molecule","molecularWeight":"178.21"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"β-glucans are polysaccharides derived from fungal cell walls that stimulate macrophages, neutrophils, and natural killer cells through Dectin-1 and complement receptor 3 binding. This activation enhances phagocytosis, cytokine production, and antimicrobial defense mechanisms. The compound is used as an immunomodulatory agent to support immune function and potentially improve outcomes in infections and certain disease states.","oneSentence":"β-1,3/1,6-D-glucan activates innate immune cells by binding to pattern recognition receptors, enhancing immune response and antimicrobial activity.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:41:33.576Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Immune support and enhancement"},{"name":"Adjunctive therapy in infections"}]},"trialDetails":[],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":6,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Imurril capsules 100mg"],"phase":"marketed","status":"active","brandName":"β-1,3/1,6-D-glucan","genericName":"β-1,3/1,6-D-glucan","companyName":"Al-Azhar University","companyId":"al-azhar-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"β-1,3/1,6-D-glucan activates innate immune cells by binding to pattern recognition receptors, enhancing immune response and antimicrobial activity. Used for Immune support and enhancement, Adjunctive therapy in infections.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}