{"disease":{"id":"white-spot-lesion","name":"white spot lesion"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06882304","title":"PREVALENCE OF WHITE SPOT LESIONS IN ENAMEL AFTER ORTHODONTIC TREATMENT IN YOUNG ADULTS","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":368,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT03865680","title":"Effect of Casein Phosphopeptide Amorphous Calcium Phosphate Fluoride Varnish on Remineralization of White Spot Lesion in Primary Teeth","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":180,"lead_sponsor_name":"Nourhan M.Aly","has_results":false},{"nct_id":"NCT04992481","title":"Fluoride Varnish, Ozone, Octenidin and WSLs in Orthodontic Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":150,"lead_sponsor_name":"Pomeranian Medical University Szczecin","has_results":false},{"nct_id":"NCT06824493","title":"Orthodontic Treatment on Oral Microbiota and Salivary Proteins","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":150,"lead_sponsor_name":"Xi'an Jiaotong University","has_results":false},{"nct_id":"NCT04382287","title":"Comparison of Remineralisation Efficacy of MI PASTE Plus® and REMIN PRO® for White Spot Lesions in Primary Teeth","phase":"NA","overall_status":"COMPLETED","enrollment_count":123,"lead_sponsor_name":"Universidad Autonoma de San Luis Potosí","has_results":false},{"nct_id":"NCT07111403","title":"Clinical Evaluation of Remineralizing Potential of Remineralizing Agents on WSLs Managment","phase":"NA","overall_status":"RECRUITING","enrollment_count":120,"lead_sponsor_name":"Mansoura University","has_results":false},{"nct_id":"NCT05710874","title":"A Prospective, Randomized, Clinical Study on the Effects of CPP-ACP-paste, Fluoride and a Combination on the Evolution of White Spot Lesions in Orthodontic Patients After Debonding.","phase":"NA","overall_status":"COMPLETED","enrollment_count":107,"lead_sponsor_name":"University Hospital, Ghent","has_results":false},{"nct_id":"NCT06821724","title":"Effect of Different Remineralizing Agents on White Spot Lesions Treatment in Children","phase":"NA","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"National Research Centre, Egypt","has_results":false},{"nct_id":"NCT06797882","title":"Preventive Effects of Silver Diamine Fluoride on Early Enamel Caries","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":99,"lead_sponsor_name":"National University of Malaysia","has_results":false},{"nct_id":"NCT04342858","title":"Prospective Randomized Controlled Trial for Prevention of Demineralization During Fixed Orthodontic Treatment","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":99,"lead_sponsor_name":"The University of Hong Kong","has_results":false},{"nct_id":"NCT06200129","title":"İmportance of Scattered White Spots Detected in the Duodenum and Their Relationship wıth Zonulin","phase":"NA","overall_status":"COMPLETED","enrollment_count":93,"lead_sponsor_name":"Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital","has_results":false},{"nct_id":"NCT03440996","title":"Comparison of Three Toothpastes for the Prevention and Reduction of White Spot Lesions","phase":"NA","overall_status":"COMPLETED","enrollment_count":90,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":false},{"nct_id":"NCT06616207","title":"Topical 10% Povidone-Iodine in Preventing White Spots","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":80,"lead_sponsor_name":"University of Washington","has_results":false},{"nct_id":"NCT05738369","title":"The Effect of Probiotic Lozenges on White Spot Lesion Development in Orthodontic Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Jordan University of Science and Technology","has_results":false},{"nct_id":"NCT07325643","title":"Effect of Hydroxyapatite Toothpaste and Mouthwash in Preventing White Spot Lesions During Orthodontic Treatment","phase":"NA","overall_status":"RECRUITING","enrollment_count":75,"lead_sponsor_name":"Heba Tahseen Almasri","has_results":false},{"nct_id":"NCT05738356","title":"Evaluation of White Spot Lesion Development Using 3 Orthodontic Adhesive Systems","phase":"NA","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Jordan University of Science and Technology","has_results":false},{"nct_id":"NCT06402500","title":"Color Masking Potential of Bioactive and ICON Materials","phase":"NA","overall_status":"RECRUITING","enrollment_count":75,"lead_sponsor_name":"King Abdullah University Hospital","has_results":false},{"nct_id":"NCT04705428","title":"Preventive Therapy of White Spot Lesions Using Different Remineralizing Agents in Children From 3 to 12 Years Old","phase":"NA","overall_status":"COMPLETED","enrollment_count":75,"lead_sponsor_name":"Universitat Internacional de Catalunya","has_results":false},{"nct_id":"NCT07247760","title":"PATIENT SATISFACTION AND MASKING OF WHITE SPOT LESIONS AFTER HOME WHITENING WITH 10% CARBAMIDE PEROXIDE","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":67,"lead_sponsor_name":"Universidad Rey Juan Carlos","has_results":false},{"nct_id":"NCT03841825","title":"Effects of Active Reminders and Motivational Techniques on Oral Hygiene and Gingival Health in Orthodontic Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":67,"lead_sponsor_name":"Virginia Commonwealth University","has_results":false},{"nct_id":"NCT06566833","title":"Effectiveness of Different Remineralizing Strategies on the Management of Early Carious Lesions in Primary Teeth","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":66,"lead_sponsor_name":"Alexandria University","has_results":false},{"nct_id":"NCT04929509","title":"P11-4 and Nanosilver Fluoride Varnish in Treatment of White Spot Carious Lesions","phase":"NA","overall_status":"UNKNOWN","enrollment_count":66,"lead_sponsor_name":"Hams Hamed Abdelrahman","has_results":false},{"nct_id":"NCT05584878","title":"Remineralizing Potential of Biomimetic Scaffolds on Enamel White Spot Lesions","phase":"NA","overall_status":"UNKNOWN","enrollment_count":63,"lead_sponsor_name":"Hams Hamed Abdelrahman","has_results":false},{"nct_id":"NCT03976583","title":"Remineralization Potential of Pearl Powder Compared to CPP-ACP on Enamel White Spot Lesions","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":62,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT03446690","title":"MI Varnish for the Prevention of White Spot Lesions","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":62,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":true},{"nct_id":"NCT05733676","title":"Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment","phase":"NA","overall_status":"RECRUITING","enrollment_count":62,"lead_sponsor_name":"University of Alberta","has_results":false},{"nct_id":"NCT06561789","title":"Remineralization Effect of βTricalcium Phosphate Nanoparticles Versus FunctionalizedβTricalcium Phosphate Nanoparticles","phase":"NA","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Aya Magdy Elsadany","has_results":false},{"nct_id":"NCT06696105","title":"Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory Setting","phase":"PHASE4","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":60,"lead_sponsor_name":"King Abdulaziz University","has_results":false},{"nct_id":"NCT05202821","title":"Clinical Evaluation of the Efficacy of SPR-G Barrier Coat Versus Fluoride Varnish Versus MI Paste in the Treatment of Early White Spot Lesions in Pediatric Patients","phase":"PHASE1","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"Ain Shams University","has_results":false},{"nct_id":"NCT04401280","title":"Bioactive Glass in the Treatment of Enamel White Spot Lesions","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Rania Salah","has_results":false},{"nct_id":"NCT03731403","title":"Remineralization Potential of MI Varnish Versus Fluoride Varnish on White Spot Lesions in Maxillary Primary Incisors","phase":"NA","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT07126366","title":"Color Stability of S-PRG Resin-Based Light-Cure Varnish and Prophylaxis Paste on White Spot Lesions","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":58,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT03973554","title":"Caries Prevention Potential of Pearl Powder Versus CPP-ACP on Enamel White Spot Lesions","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":58,"lead_sponsor_name":"Ruba Alaa El Din Adel El Damarisy","has_results":false},{"nct_id":"NCT03738839","title":"A Comparative Assessment of Orthodontic Treatment Outcomes Using the Quantitative Light-Induced Fluorescence Method","phase":"NA","overall_status":"COMPLETED","enrollment_count":51,"lead_sponsor_name":"TC Erciyes University","has_results":false},{"nct_id":"NCT05764187","title":"Incidence of White Spot Lesions Around Ceramic Brackets Compared With Metal Brackets","phase":"NA","overall_status":"COMPLETED","enrollment_count":51,"lead_sponsor_name":"Jordan University of Science and Technology","has_results":false},{"nct_id":"NCT06358066","title":"The Remineralization of Early Enamel Caries in Permanent Teeth","phase":"PHASE1","overall_status":"NOT_YET_RECRUITING","enrollment_count":50,"lead_sponsor_name":"Tanta University","has_results":false},{"nct_id":"NCT05757440","title":"Effect of Low-viscosity Resin Infiltration on Color Change of Enamel White Spot Lesions","phase":"NA","overall_status":"COMPLETED","enrollment_count":49,"lead_sponsor_name":"National Research Centre, Egypt","has_results":false},{"nct_id":"NCT05771077","title":"Effect of Poly Amido Amine Dendrimer, Nano-hydroxyapatite","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":45,"lead_sponsor_name":"Egymedicalpedia","has_results":false},{"nct_id":"NCT06833970","title":"Toothpastes With Different Contents and Tooth Color","phase":"","overall_status":"COMPLETED","enrollment_count":45,"lead_sponsor_name":"Taner OZTURK, DDS, MS","has_results":false},{"nct_id":"NCT06749977","title":"P11-4 and Fluoride Varnish for Remineralization of Post-orthodontic Lesions","phase":"NA","overall_status":"COMPLETED","enrollment_count":45,"lead_sponsor_name":"Medical University of Sofia","has_results":false},{"nct_id":"NCT07291830","title":"A Novel Remineralizing Self-Etch Primer for Orthodontic Bracket Bonding","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":45,"lead_sponsor_name":"University of Baghdad","has_results":false},{"nct_id":"NCT05871619","title":"Combined Application of Diode Laser and Different Remineralizing Agents on White Spot Lesions","phase":"NA","overall_status":"COMPLETED","enrollment_count":45,"lead_sponsor_name":"Al-Azhar University","has_results":false},{"nct_id":"NCT05868603","title":"Effect of Different Remineralization Gels","phase":"NA","overall_status":"UNKNOWN","enrollment_count":45,"lead_sponsor_name":"Marmara University","has_results":false},{"nct_id":"NCT07086235","title":"Remineralization Capacity and Patient Satisfaction of Self-Assembling Peptide With Fluoride Versus Tooth Protective Coating With Surface Pre-Reacted Glass on White Spot Lesions","phase":"NA","overall_status":"COMPLETED","enrollment_count":44,"lead_sponsor_name":"Nahda University","has_results":false},{"nct_id":"NCT06166849","title":"Clinical Evaluation of an Experimental Remineralization Product","phase":"NA","overall_status":"COMPLETED","enrollment_count":43,"lead_sponsor_name":"Ivoclar Vivadent AG","has_results":true},{"nct_id":"NCT06905379","title":"Remineralization Efficacy of Moringa Oleifera Varnish Vs MI Varnish in Initial Carious Lesions Over 6 Months Follow Up: a Randomized Controlled Clinical Trial","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":40,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT06834464","title":"Effect of Nanohydroxyapatite Paste After Different Pretreatment Techniques on White Spot White Spot Lesions","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"National Research Centre, Egypt","has_results":false},{"nct_id":"NCT04908293","title":"Home Remineralization of White Spot Lesions With Two Different Toothpastes.","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"University of Pavia","has_results":false},{"nct_id":"NCT04560478","title":"Comparing Fluoride Varnish and Sealant to Prevent White Spots in Orthodontic Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"Texas A&M University","has_results":false},{"nct_id":"NCT07229105","title":"Comparative Effectiveness of Remineralization Agents on Attachment-Associated Demineralization in Clear Aligner Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"Bezmialem Vakif University","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}