{"disease":{"id":"vascular-malformations","name":"vascular malformations"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03774017","title":"Research on Hybrid Operation Technique in the Treatment of Complex Brain Arteriovenous Malformations","phase":"NA","overall_status":"UNKNOWN","enrollment_count":1200,"lead_sponsor_name":"Ministry of Science and Technology of the People´s Republic of China","has_results":false},{"nct_id":"NCT05113420","title":"The Efficacy and Safety of Different Phlebotonic Drugs in Children With Venous Malformations","phase":"","overall_status":"UNKNOWN","enrollment_count":1000,"lead_sponsor_name":"Center for Vascular Pathology, Moscow","has_results":false},{"nct_id":"NCT02638389","title":"Efficacy and Safety of Sirolimus in Vascular Anomalies That Are Refractory to Standard Care","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":250,"lead_sponsor_name":"Cliniques universitaires Saint-Luc- Université Catholique de Louvain","has_results":false},{"nct_id":"NCT07404670","title":"Microwave Ablation for Treatment of Vascular Malformations: Efficacy and Safety","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":150,"lead_sponsor_name":"Chengdu University of Traditional Chinese Medicine","has_results":false},{"nct_id":"NCT06040580","title":"Can we Use Resting-state fMRI and CSD Fiber Tractography for Presurgical Mapping?","phase":"","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Universitaire Ziekenhuizen KU Leuven","has_results":false},{"nct_id":"NCT06975618","title":"Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of CYH33 in Patients With PIK3CA-related Overgrowth Spectrum (PROS) and PIK3CA-related Vascular Malformations (PRVM)","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":141,"lead_sponsor_name":"Haihe Biopharma Co., Ltd.","has_results":false},{"nct_id":"NCT03429127","title":"Normal Saline Vrs Balanced i.v. Fluids in Neurosurgery","phase":"","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"Clinical Hospital Centre Zagreb","has_results":false},{"nct_id":"NCT03987152","title":"Treatment of Congenital Vascular Malformations Using Sirolimus: Improving Quality of Life","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":75,"lead_sponsor_name":"Radboud University Medical Center","has_results":false},{"nct_id":"NCT04921722","title":"Percutaneous Administration of Sirolimus in the Treatment of Superficial Complicated Vascular Anomalies","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":75,"lead_sponsor_name":"Children's Hospital of Fudan University","has_results":false},{"nct_id":"NCT07477548","title":"A Study to Evaluate the Efficacy and Safety of Everolimus in Patients With Teratment-refractory Vascular Anomalies","phase":"PHASE2","overall_status":"NOT_YET_RECRUITING","enrollment_count":67,"lead_sponsor_name":"Yonsei University","has_results":false},{"nct_id":"NCT06189092","title":"Treatment of Low-flow Venous Malformations With Electrosclerotherapy. Prospective Observational Study","phase":"","overall_status":"RECRUITING","enrollment_count":65,"lead_sponsor_name":"Istituto Ortopedico Rizzoli","has_results":false},{"nct_id":"NCT03972592","title":"Topical Sirolimus in Cutaneous Lymphatic Malformations","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":55,"lead_sponsor_name":"University Hospital, Tours","has_results":false},{"nct_id":"NCT05563831","title":"National Evaluation of Patients With PIK3CA-Related Overgrowth Spectrum (PROS)","phase":"","overall_status":"COMPLETED","enrollment_count":28,"lead_sponsor_name":"Institut National de la Santé Et de la Recherche Médicale, France","has_results":false},{"nct_id":"NCT05494710","title":"Bleomycin Electrosclerotherapy Treatment of Vascular Malformations: A Feasibility Study","phase":"NA","overall_status":"UNKNOWN","enrollment_count":20,"lead_sponsor_name":"South Tees Hospitals NHS Foundation Trust","has_results":false},{"nct_id":"NCT04637997","title":"Influence of Flat-knitted Compression Stockings Class I and II on Venous Malformations","phase":"NA","overall_status":"COMPLETED","enrollment_count":18,"lead_sponsor_name":"University Hospital Erlangen","has_results":true},{"nct_id":"NCT06994260","title":"Diagnostic Imaging of Vascular Malformations Using MSOT and ULM","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":15,"lead_sponsor_name":"University Hospital Erlangen","has_results":false},{"nct_id":"NCT02991352","title":"Stereotactic MRI Based Image Guidance for the Treatment of Vascular Malformations - a Pilot Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":10,"lead_sponsor_name":"Insel Gruppe AG, University Hospital Bern","has_results":false},{"nct_id":"NCT07037238","title":"An Open-Label, Single-Arm Exploratory Clinical Study of Everolimus for the Treatment of Vascular Malformations","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":10,"lead_sponsor_name":"Xuanwu Hospital, Beijing","has_results":false},{"nct_id":"NCT06160739","title":"Role of Sirolimus in Treatment of Microcystic , Mixed Lymphatic and Vascular Malformations","phase":"","overall_status":"UNKNOWN","enrollment_count":10,"lead_sponsor_name":"Sohag University","has_results":false},{"nct_id":"NCT04836884","title":"Vascular Anomaly Pathology and Genomics Biopsy Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":3,"lead_sponsor_name":"Mayo Clinic","has_results":false}],"total":20},"guidelines":[],"source":"Drug Landscape verified database"}