{"disease":{"id":"vaginal-hysterectomy","name":"vaginal hysterectomy"},"drugs":{"marketed":[{"drug_id":"ampicillin","indication_name":"Vaginal Hysterectomy Infection Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Unasyn","generic_name":"AMPICILLIN","company_name":"Bristol-Myers Squibb","drug_phase":"marketed","molecular_target":"Transient receptor potential cation channel subfamily M member 4","drug_class":"Penicillin-class Antibacterial","quality_score":53,"revenue":null,"mechanism":""},{"drug_id":"piperacillin","indication_name":"Vaginal Hysterectomy Infection Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Pipracil","generic_name":"PIPERACILLIN","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"piperacillin","quality_score":10,"revenue":null,"mechanism":"Pipracil works by inhibiting bacterial cell wall synthesis, ultimately leading to cell lysis and death."},{"drug_id":"alatrofloxacin","indication_name":"Vaginal Hysterectomy Infection Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"ALATROFLOXACIN","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"","drug_class":"alatrofloxacin","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"cefoxitin","indication_name":"Vaginal Hysterectomy Infection Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Mefoxin In Sodium Chloride 0.9% In Plastic Container","generic_name":"CEFOXITIN","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"Cephalosporin Antibacterial","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"norfloxacin","indication_name":"Vaginal Hysterectomy Infection Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Noroxin","generic_name":"NORFLOXACIN","company_name":"","drug_phase":"marketed","molecular_target":"Gamma-aminobutyric acid receptor subunit alpha-1","drug_class":"Quinolone Antimicrobial","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"ofloxacin","indication_name":"Vaginal Hysterectomy Infection Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Floxin","generic_name":"OFLOXACIN","company_name":"","drug_phase":"marketed","molecular_target":"Histamine H3 receptor","drug_class":"Quinolone Antimicrobial [EPC]","quality_score":65,"revenue":null,"mechanism":""},{"drug_id":"ofloxacine","indication_name":"Vaginal Hysterectomy Infection Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Ofloxacine","company_name":"Assistance Publique - Hôpitaux de Paris","drug_phase":"phase_3","molecular_target":"Gamma-aminobutyric acid receptor subunit alpha-2, Histamine H3 receptor, Muscarinic acetylcholine receptor M1","drug_class":"","quality_score":null,"revenue":null,"mechanism":null}],"pipeline":[],"offLabel":[],"totalMarketed":7,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03446950","title":"Study Investigating Role of Unalike Patient Positioning on PROMIS Scores","phase":"NA","overall_status":"COMPLETED","enrollment_count":155,"lead_sponsor_name":"University of Louisville","has_results":false},{"nct_id":"NCT04886791","title":"Vaginal NOTES Hysterectomy Versus Vaginal Hysterectomy","phase":"NA","overall_status":"RECRUITING","enrollment_count":124,"lead_sponsor_name":"Zuyderland Medisch Centrum","has_results":false},{"nct_id":"NCT06982157","title":"A Comparison Between Vaginal Sacrospinous Ligament Fixation and Laparoscopic Uterosacral Ligament Suspension as a Uterine Preserving Surgery for Pelvic Organ Prolapse","phase":"","overall_status":"COMPLETED","enrollment_count":111,"lead_sponsor_name":"Hillel Yaffe Medical Center","has_results":false},{"nct_id":"NCT05921071","title":"Do Patients Who Received Tranexamic Acid in Vaginal Hysterectomy Loose Les Blood, Comparing to Patients Who Did Not?","phase":"NA","overall_status":"RECRUITING","enrollment_count":80,"lead_sponsor_name":"Wolfson Medical Center","has_results":false},{"nct_id":"NCT06429605","title":"Evaluating the Efficacy and Safety of Preoperative Administration of Duloxetine for Pain Management in Women Undergoing Hysterectomy Via Vaginal Route","phase":"NA","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"Erzincan Military Hospital","has_results":false},{"nct_id":"NCT04804826","title":"Same Day Discharge Following Pelvic Reconstructive Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":54,"lead_sponsor_name":"TriHealth Inc.","has_results":false},{"nct_id":"NCT03883347","title":"Sedation With Dexmedetomidine Versus Remifentanil in Urogynecological Surgery Under Spinal Anaesthesia","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":50,"lead_sponsor_name":"University of Athens","has_results":false},{"nct_id":"NCT05031117","title":"Dural Puncture Epidural Technique For Vaginal Procedures","phase":"NA","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"Cairo University","has_results":false},{"nct_id":"NCT04440475","title":"Tap Block vs Conventional Pain Medication for Patients Undergoing Robotic Sacrocolpopexy","phase":"NA","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"ProMedica Health System","has_results":false},{"nct_id":"NCT03907033","title":"Liposomal Bupivacaine in Vaginal Hysterectomy","phase":"PHASE4","overall_status":"TERMINATED","enrollment_count":28,"lead_sponsor_name":"Mayo Clinic","has_results":true},{"nct_id":"NCT05418764","title":"Effect of Validated Skills Simulation With the Miya Model","phase":"NA","overall_status":"COMPLETED","enrollment_count":25,"lead_sponsor_name":"Wake Forest University Health Sciences","has_results":false},{"nct_id":"NCT05332132","title":"Ex Vivo Study of the Heracure Device for Intra-uterine Morcellation After Vaginal or Laparoscopic Hysterectomy","phase":"NA","overall_status":"UNKNOWN","enrollment_count":10,"lead_sponsor_name":"Heracure Medical Ltd.","has_results":false},{"nct_id":"NCT03228654","title":"Electrosurgical Unipolar Vessel Sealing in Vaginal Hysterectomy","phase":"PHASE4","overall_status":"TERMINATED","enrollment_count":10,"lead_sponsor_name":"Ain Shams University","has_results":false},{"nct_id":"NCT04797585","title":"Vaginal Hysterectomy vs Supracervical Hysterectomy at the Time of Sacrocolpopexy","phase":"NA","overall_status":"TERMINATED","enrollment_count":3,"lead_sponsor_name":"The Cleveland Clinic","has_results":true}],"total":14},"guidelines":[],"source":"Drug Landscape verified database"}