{"disease":{"id":"transcatheter-aortic-valve-replacement","name":"transcatheter aortic valve replacement"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT07267117","title":"Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease","phase":"","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT06000943","title":"Ischemic And Bleeding Risk Assessment After TAVR","phase":"","overall_status":"RECRUITING","enrollment_count":2500,"lead_sponsor_name":"Niguarda Hospital","has_results":false},{"nct_id":"NCT04139616","title":"Prospective Validation of a Pre-Specified Algorithm for the Management of Conduction Disturbances Following TAVR","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec","has_results":false},{"nct_id":"NCT02556203","title":"Global Study Comparing a rivAroxaban-based Antithrombotic Strategy to an antipLatelet-based Strategy After Transcatheter aortIc vaLve rEplacement to Optimize Clinical Outcomes","phase":"PHASE3","overall_status":"TERMINATED","enrollment_count":1653,"lead_sponsor_name":"Bayer","has_results":true},{"nct_id":"NCT02664649","title":"Anti-Thrombotic Strategy After Trans-Aortic Valve Implantation for Aortic Stenosis","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":1510,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT05283356","title":"Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":1206,"lead_sponsor_name":"Fundacin Biomedica Galicia Sur","has_results":false},{"nct_id":"NCT05235555","title":"EffecTAVI Registry","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Federico II University","has_results":false},{"nct_id":"NCT06697249","title":"Feasibility of Valve-in-Root Transcatheter Aortic Valve Implantation in 363 Patients After Aortic Root Replacement and Repair","phase":"","overall_status":"COMPLETED","enrollment_count":760,"lead_sponsor_name":"Alicja Zientara","has_results":false},{"nct_id":"NCT07107568","title":"Assessment of Coronary Artery Disease Before Transcatheter Aortic Valve Replacement: A Randomized, Multicenter, Non-Inferiority Trial","phase":"NA","overall_status":"RECRUITING","enrollment_count":700,"lead_sponsor_name":"Medical University Innsbruck","has_results":false},{"nct_id":"NCT05375474","title":"Antithrombotic Strategy Based on Clinical Events and 4D-CT for Patients After TAVR","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":650,"lead_sponsor_name":"China National Center for Cardiovascular Diseases","has_results":false},{"nct_id":"NCT06559332","title":"Coronary Artery Disease Assessment Strategies in TAVI Patients","phase":"NA","overall_status":"RECRUITING","enrollment_count":546,"lead_sponsor_name":"Insel Gruppe AG, University Hospital Bern","has_results":false},{"nct_id":"NCT06953206","title":"Prospective, Long-term Evaluation of the SAPIEN 3 Ultra RESILIA Valve","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":500,"lead_sponsor_name":"Institut für Pharmakologie und Präventive Medizin","has_results":false},{"nct_id":"NCT06857201","title":"RAFT-TAVR PACE: LBBAP Vs. RVP Post-TAVR in Patients Requiring PPI","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":430,"lead_sponsor_name":"London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's","has_results":false},{"nct_id":"NCT04982406","title":"Transcatheter Aortic Valve Replacement (TAVR) Effects on Cardiac Conduction System","phase":"","overall_status":"COMPLETED","enrollment_count":409,"lead_sponsor_name":"Beth Israel Deaconess Medical Center","has_results":false},{"nct_id":"NCT05657912","title":"Cara CDRS (Conduction Disturbance Risk Score) 1.0","phase":"","overall_status":"COMPLETED","enrollment_count":355,"lead_sponsor_name":"Cara Medical Ltd","has_results":false},{"nct_id":"NCT01627691","title":"REPRISE II: REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of Lotus™ Valve System","phase":"NA","overall_status":"COMPLETED","enrollment_count":250,"lead_sponsor_name":"Boston Scientific Corporation","has_results":true},{"nct_id":"NCT07370467","title":"Transcatheter Mitral and Tricuspid Interventions: a Cardiac Magnetic Resonance Study","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":250,"lead_sponsor_name":"Centro Cardiologico Monzino","has_results":false},{"nct_id":"NCT05654792","title":"Prognostic Factors in NOP-LBBB After TAVI","phase":"","overall_status":"UNKNOWN","enrollment_count":230,"lead_sponsor_name":"Central Hospital, Nancy, France","has_results":false},{"nct_id":"NCT06212050","title":"Feasibility, Safety, and Effectiveness of the ACURATE neo2 Transcatheter Heart Valve for Severe Bicuspid Aortic Stenosis","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":200,"lead_sponsor_name":"National University of Ireland, Galway, Ireland","has_results":false},{"nct_id":"NCT05259241","title":"ADAPT Transcatheter Aortic Valve Intervention (TAVI & Chronic Total Occlusion Percutaneous Coronary Intervention (CTO PCI)","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Erasmus Medical Center","has_results":false},{"nct_id":"NCT04649190","title":"Post-TAVI Coronary Access Study","phase":"","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Sheba Medical Center","has_results":false},{"nct_id":"NCT03522454","title":"The PERFORM-TAVR Trial","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Jewish General Hospital","has_results":false},{"nct_id":"NCT07455292","title":"Phenotyping Left Ventricle Failure With Hemodynamic Biomarkers From 4D Flow Magnetic Resonance Imaging","phase":"NA","overall_status":"RECRUITING","enrollment_count":190,"lead_sponsor_name":"IRCCS Policlinico S. Donato","has_results":false},{"nct_id":"NCT02735902","title":"Anticoagulation Alone Versus Anticoagulation and Aspirin Following Transcatheter Aortic Valve Interventions (1:1)","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":170,"lead_sponsor_name":"Centre Hospitalier Universitaire de Nīmes","has_results":false},{"nct_id":"NCT04107038","title":"Monitored Anesthesia Care vs. General Anesthesia for Transcatheter Aortic Valve Replacement","phase":"NA","overall_status":"COMPLETED","enrollment_count":170,"lead_sponsor_name":"Medical University of South Carolina","has_results":false},{"nct_id":"NCT05758701","title":"CT TAVR Abdomen Study","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":164,"lead_sponsor_name":"University of Maryland, Baltimore","has_results":false},{"nct_id":"NCT03801460","title":"Physiological Reconditioning Program Administered Remotely in Patients Undergoing Transcatheter Aortic Valve Replacement: A Pilot Study","phase":"NA","overall_status":"UNKNOWN","enrollment_count":160,"lead_sponsor_name":"Unity Health Toronto","has_results":false},{"nct_id":"NCT05217888","title":"The Sentinel Registry","phase":"","overall_status":"COMPLETED","enrollment_count":158,"lead_sponsor_name":"Duk-Woo Park, MD","has_results":false},{"nct_id":"NCT07365345","title":"Frequency of Electrical Acupoint Stimulation on Hypotension in TAVR Patients","phase":"NA","overall_status":"RECRUITING","enrollment_count":150,"lead_sponsor_name":"Air Force Military Medical University, China","has_results":false},{"nct_id":"NCT05024942","title":"LUS in Aortic Stenosis Patients Undergoing TAVR","phase":"","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Catholic University of the Sacred Heart","has_results":false},{"nct_id":"NCT06420830","title":"Valve Performance of the SAPIEN 3 Ultra RESILIA Valve: A Prospective Registry With Central Echocardiography Analysis.","phase":"","overall_status":"RECRUITING","enrollment_count":150,"lead_sponsor_name":"Institut universitaire de cardiologie et de pneumologie de Québec, University Laval","has_results":false},{"nct_id":"NCT06040398","title":"The JUMPSTART Program: Encouraging Early Mobilization and Optimizing Recovery of TAVR Patients' Post-hospital Discharge","phase":"","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Hamilton Health Sciences Corporation","has_results":false},{"nct_id":"NCT04573049","title":"The Effectiveness and Safety of Levosimendan in Patients With Severe Aortic Stenosis and Heart Failure Undergoing Transcatheter Aortic Valve Replacement","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":124,"lead_sponsor_name":"China National Center for Cardiovascular Diseases","has_results":false},{"nct_id":"NCT05881291","title":"Efficacy and Safety of Ciprofol for General Anaesthesia in Patients Undergoing Transcatheter Aortic Valve Replacement","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":124,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT06818084","title":"TRanscAtheter TreatMent of PurE Aortic Regurgitation With VitaFlow Liberty System","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":120,"lead_sponsor_name":"Ruijin Hospital","has_results":false},{"nct_id":"NCT04870424","title":"Colchicine for Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":120,"lead_sponsor_name":"Insel Gruppe AG, University Hospital Bern","has_results":false},{"nct_id":"NCT07329660","title":"Crystalloid vs Colloid for Hemodynamics During Anesthesia Induction in TAVR Patients","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":116,"lead_sponsor_name":"Air Force Military Medical University, China","has_results":false},{"nct_id":"NCT07148973","title":"Outcomes for Patients With Ascending Aortic Dilation Who Underwent TAVR","phase":"","overall_status":"COMPLETED","enrollment_count":101,"lead_sponsor_name":"zjq","has_results":false},{"nct_id":"NCT04454177","title":"SMART Watch Facilitated Early Discharge in Patients Undergoing Transcatheter Aortic Valve Replacement","phase":"","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT05750927","title":"Aortic Stenosis With COmplex PCI (ASCOP) Features Retrospective Registry on Contemporary Management and Outcomes","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Niguarda Hospital","has_results":false},{"nct_id":"NCT05779787","title":"COronary Re-engageMent aFter randOm NavitoR alignmenT (COMFORT STUDY)","phase":"","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"Niguarda Hospital","has_results":false},{"nct_id":"NCT06896227","title":"TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics","phase":"NA","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"Heinrich-Heine University, Duesseldorf","has_results":false},{"nct_id":"NCT03649594","title":"Risk Stratification Post TAVI Using TEG","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"Torben Pottgiesser","has_results":false},{"nct_id":"NCT06983938","title":"This Study Will Evaluate the Safety and Potential Complications of Dual ProGlide vs Single ProGlide and Angioseal for Common Femoral Arteriotomy Closure Following Transcatheter Aortic Valve Replacement","phase":"NA","overall_status":"COMPLETED","enrollment_count":92,"lead_sponsor_name":"Baylor Research Institute","has_results":true},{"nct_id":"NCT04281771","title":"Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRI","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":92,"lead_sponsor_name":"Radboud University Medical Center","has_results":false},{"nct_id":"NCT04517955","title":"TAVI in Intermediate Risk Septuagenarians With Risk Factors Not Captured by the Traditional Surgical Risk Scores","phase":"","overall_status":"UNKNOWN","enrollment_count":80,"lead_sponsor_name":"University of Athens","has_results":false},{"nct_id":"NCT03747432","title":"Comparison of Procedural Sedation With Propofol and Dexmedetomidine During Transcatheter Aortic Valve Implantation","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":70,"lead_sponsor_name":"University Medical Centre Ljubljana","has_results":false},{"nct_id":"NCT04952909","title":"The ShortCut™ Study Protocol","phase":"NA","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Pi-cardia","has_results":true},{"nct_id":"NCT05075590","title":"Coronary Access After Supra-Annular THV Implantation","phase":"NA","overall_status":"UNKNOWN","enrollment_count":50,"lead_sponsor_name":"University of British Columbia","has_results":false},{"nct_id":"NCT05791344","title":"Intra-procedural ECG Changes During TAVR","phase":"","overall_status":"TERMINATED","enrollment_count":43,"lead_sponsor_name":"Cara Medical Ltd","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}