{"disease":{"id":"tourette-s-syndrome","name":"tourette s syndrome"},"drugs":{"marketed":[{"drug_id":"haloperidol","indication_name":"Gilles de la Tourette's syndrome","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Haldol","generic_name":"haloperidol","company_name":"Johnson & Johnson (Janssen)","drug_phase":"marketed","molecular_target":"3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase, 5-hydroxytryptamine receptor 1E, 5-hydroxytryptamine receptor 5A","drug_class":"Typical Antipsychotic [EPC]","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"pimozide","indication_name":"Gilles de la Tourette's syndrome","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Orap","generic_name":"PIMOZIDE","company_name":"Teva","drug_phase":"marketed","molecular_target":"5-hydroxytryptamine receptor 7","drug_class":"Typical Antipsychotic [EPC]","quality_score":10,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":2,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04806620","title":"Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research","phase":"","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Brain Inflammation Collaborative","has_results":false},{"nct_id":"NCT00001260","title":"Brain Tissue Collection for Neuropathological Studies","phase":"","overall_status":"TERMINATED","enrollment_count":2161,"lead_sponsor_name":"National Institute of Mental Health (NIMH)","has_results":false},{"nct_id":"NCT06848959","title":"Development and Application of a Diagnosis and Treatment System for Children's Brain Diseases Based on Knowledge Graphs and Large Models","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Yun Liu,PhD","has_results":false},{"nct_id":"NCT01019343","title":"Physiological Investigations of Movement Disorders","phase":"NA","overall_status":"COMPLETED","enrollment_count":1273,"lead_sponsor_name":"National Institute of Neurological Disorders and Stroke (NINDS)","has_results":false},{"nct_id":"NCT03225430","title":"Evaluation of a Cognitive Psychophysiological Treatment for Tourette Syndrome and Tic Disorders","phase":"NA","overall_status":"COMPLETED","enrollment_count":144,"lead_sponsor_name":"Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal","has_results":false},{"nct_id":"NCT04114539","title":"Ecopipam Tablets to Study Tourette Syndrome in Children and Adolescents - Open Label Extension","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":124,"lead_sponsor_name":"Emalex Biosciences Inc.","has_results":true},{"nct_id":"NCT04805385","title":"Effects of Lactobacillus Plantarum PS128 in Patients With Tourette's Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":121,"lead_sponsor_name":"China Medical University Hospital","has_results":false},{"nct_id":"NCT04449003","title":"Influence of Stress and Psychiatric Symptoms on Children With Tourette Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":66,"lead_sponsor_name":"Vanderbilt University Medical Center","has_results":false},{"nct_id":"NCT05233306","title":"Investigations of the Pathophysiology of Gilles de la Tourette Syndrome. Part 2: 7T MRI","phase":"","overall_status":"COMPLETED","enrollment_count":65,"lead_sponsor_name":"Max Planck Institute for Human Cognitive and Brain Sciences","has_results":false},{"nct_id":"NCT06361004","title":"Exploring DBS Efficacy in Treatment-refractory Tourette's Syndrome","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":60,"lead_sponsor_name":"Xuanwu Hospital, Beijing","has_results":false},{"nct_id":"NCT04578912","title":"Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics","phase":"NA","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"University of Minnesota","has_results":true},{"nct_id":"NCT00368433","title":"Hypersensitivity in Tourette Syndrome","phase":"","overall_status":"COMPLETED","enrollment_count":46,"lead_sponsor_name":"National Institute of Neurological Disorders and Stroke (NINDS)","has_results":false},{"nct_id":"NCT05696769","title":"Tourette Discrimination (TD) Stigma Scale","phase":"","overall_status":"COMPLETED","enrollment_count":43,"lead_sponsor_name":"Wake Forest University Health Sciences","has_results":false},{"nct_id":"NCT05232955","title":"Investigations of the Pathophysiology of Gilles de la Tourette Syndrome. Part 1: Simultaneous PET and 3T MRI","phase":"","overall_status":"COMPLETED","enrollment_count":40,"lead_sponsor_name":"Max Planck Institute for Human Cognitive and Brain Sciences","has_results":false},{"nct_id":"NCT04087616","title":"Internet-based CBIT for Children With Chronic Tics","phase":"NA","overall_status":"UNKNOWN","enrollment_count":40,"lead_sponsor_name":"Tel Aviv Medical Center","has_results":false},{"nct_id":"NCT02205918","title":"Brain-Behavior Interactions in Tic Suppression","phase":"","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"University of Minnesota","has_results":false},{"nct_id":"NCT05434546","title":"A Study to Explore the Effect of Sepranolone in Tourette Syndrome","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":26,"lead_sponsor_name":"Asarina Pharma","has_results":false},{"nct_id":"NCT03765463","title":"Extinction Learning in Youth With Tourette Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":20,"lead_sponsor_name":"Johns Hopkins University","has_results":false},{"nct_id":"NCT05628805","title":"Theta Burst Stimulation to Improve Inhibitory Motor Physiology in Tourette Syndrome","phase":"NA","overall_status":"COMPLETED","enrollment_count":16,"lead_sponsor_name":"Children's Hospital Medical Center, Cincinnati","has_results":false}],"total":19},"guidelines":[],"source":"Drug Landscape verified database"}