{"disease":{"id":"st-abr","name":"st abr"},"drugs":{"marketed":[{"drug_id":"neo-bladder-construct","indication_name":"BRAF V600E or V600K Mutation-Positive Unresectable or Metastatic Melanoma (Combination with Dabrafenib)","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"\"Neo-Bladder\" Construct","company_name":"Wake Forest University Health Sciences","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":29,"revenue":null,"mechanism":null},{"drug_id":"chembl-chembl2103875","indication_name":"BRAF V600E or V600K Mutation-Positive Unresectable or Metastatic Melanoma (Combination with Dabrafenib)","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"TRAMETINIB","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":5,"revenue":null,"mechanism":null},{"drug_id":"chembl-chembl2103875","indication_name":"BRAF V600E Mutation-Positive Metastatic NSCLC (Combination with Dabrafenib)","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"TRAMETINIB","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":5,"revenue":null,"mechanism":null},{"drug_id":"chembl-chembl2103875","indication_name":"BRAF V600E Mutation-Positive Locally Advanced or Metastatic Anaplastic Thyroid Cancer (Combination with Dabrafenib)","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"TRAMETINIB","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":5,"revenue":null,"mechanism":null},{"drug_id":"chembl-chembl2103875","indication_name":"BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors (Combination with Dabrafenib)","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"TRAMETINIB","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":5,"revenue":null,"mechanism":null}],"pipeline":[],"offLabel":[],"totalMarketed":5,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06065852","title":"National Registry of Rare Kidney Diseases","phase":"","overall_status":"RECRUITING","enrollment_count":35000,"lead_sponsor_name":"UK Kidney Association","has_results":false},{"nct_id":"NCT06653374","title":"Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns","phase":"","overall_status":"COMPLETED","enrollment_count":26000,"lead_sponsor_name":"HOSPITAL GINECO OBSTETRICO ISIDRO AYORA","has_results":false},{"nct_id":"NCT06607471","title":"Multimodal and Multidisciplinary Approach to Optimize Diagnostic, Prognostic, and Therapeutic Management of Patients with Non-ischemic Cardiomyopathies and Arrhythmogenic-inflammatory Phenotypes: a Multicenter, Observational, Retrospective and Prospective Registry Study.","phase":"","overall_status":"RECRUITING","enrollment_count":15000,"lead_sponsor_name":"Scientific Institute San Raffaele","has_results":false},{"nct_id":"NCT03047369","title":"The Myelin Disorders Biorepository Project","phase":"","overall_status":"RECRUITING","enrollment_count":12000,"lead_sponsor_name":"Children's Hospital of Philadelphia","has_results":false},{"nct_id":"NCT07263490","title":"PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)","phase":"","overall_status":"RECRUITING","enrollment_count":462,"lead_sponsor_name":"Copenhagen University Hospital, Hvidovre","has_results":false},{"nct_id":"NCT07025772","title":"Shaping Habitual Impulses For a Tobacco-free Style","phase":"NA","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"University of Houston","has_results":false},{"nct_id":"NCT05847361","title":"BH4 Blood Levels Variations in Pre Eclamptic Women","phase":"","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"University Tunis El Manar","has_results":false},{"nct_id":"NCT02699190","title":"LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies","phase":"","overall_status":"COMPLETED","enrollment_count":236,"lead_sponsor_name":"Children's Hospital of Philadelphia","has_results":true},{"nct_id":"NCT04943991","title":"Fabry Disease in High-risk Patients With Left Ventricular Hypertrophy: Prevalence and Implementation of a Clinical Score","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":200,"lead_sponsor_name":"Wuerzburg University Hospital","has_results":false},{"nct_id":"NCT05461469","title":"CDL Validation Study","phase":"","overall_status":"COMPLETED","enrollment_count":104,"lead_sponsor_name":"Occyo GmbH","has_results":false},{"nct_id":"NCT06653985","title":"Intra-articular Corticosteroid With Hyaluronic Acid Plus Physiotherapy for Hip Pathologies (NON-OP HIP)","phase":"NA","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"ArthroBiologix Inc.","has_results":false},{"nct_id":"NCT05974423","title":"Randomized Trial of Narcotic vs Non-Narcotic Pain Modulation After Labrum Repair","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":60,"lead_sponsor_name":"The Cooper Health System","has_results":false},{"nct_id":"NCT03407612","title":"Outcomes of CPM Usage Following Arthroscopic Acetabular Labral Repair","phase":"NA","overall_status":"COMPLETED","enrollment_count":54,"lead_sponsor_name":"Ohio State University","has_results":true}],"total":13},"guidelines":[],"source":"Drug Landscape verified database"}