{"disease":{"id":"somatic-mutation","name":"somatic mutation"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06895681","title":"UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":50000,"lead_sponsor_name":"University of California, San Francisco","has_results":false},{"nct_id":"NCT06585800","title":"Exploring the Landscape of Somatic Mutations in Human Tissue","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":1800,"lead_sponsor_name":"The Wellcome Sanger Institute","has_results":false},{"nct_id":"NCT06851052","title":"SMS - Study of Somatic Mutations Using Genome Sequencing","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":600,"lead_sponsor_name":"The Wellcome Sanger Institute","has_results":false},{"nct_id":"NCT01953926","title":"Basket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":582,"lead_sponsor_name":"Puma Biotechnology, Inc.","has_results":true},{"nct_id":"NCT06357845","title":"Linking Somatic Mutation Rate With Baseline Exposure in East Palestine","phase":"NA","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Case Comprehensive Cancer Center","has_results":false},{"nct_id":"NCT04788927","title":"Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":400,"lead_sponsor_name":"Rigshospitalet, Denmark","has_results":false},{"nct_id":"NCT05364294","title":"Molecular Diagnosis of Systemic Autoinflammatory Diseases","phase":"","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"Institut National de la Santé Et de la Recherche Médicale, France","has_results":false},{"nct_id":"NCT03286842","title":"To Study Clinical Effectiveness and Safety of Olaparib Monotherapy in Metastatic Breast Cancer Patients.","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":256,"lead_sponsor_name":"AstraZeneca","has_results":true},{"nct_id":"NCT06656767","title":"Somatic Mutation in Chronic Liver Disease","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":250,"lead_sponsor_name":"The Wellcome Sanger Institute","has_results":false},{"nct_id":"NCT03344965","title":"Olaparib In Metastatic Breast Cancer","phase":"PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":114,"lead_sponsor_name":"Beth Israel Deaconess Medical Center","has_results":false},{"nct_id":"NCT04516083","title":"Lynch Syndrome Can be Diagnosed Just From Somatic Mismatch Repair Mutation","phase":"","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"RWJ Barnabas Health at Jersey City Medical Center","has_results":false},{"nct_id":"NCT05735717","title":"MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":70,"lead_sponsor_name":"Masonic Cancer Center, University of Minnesota","has_results":false},{"nct_id":"NCT06832150","title":"SMS 2: Impact of Cancer Therapy on the Somatic Mutational Landscape of Normal Tissues","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":60,"lead_sponsor_name":"The Wellcome Sanger Institute","has_results":false},{"nct_id":"NCT06861647","title":"iSITE: Investigation of Somatic Alterations in Tumours of the Eye","phase":"","overall_status":"COMPLETED","enrollment_count":58,"lead_sponsor_name":"The Wellcome Sanger Institute","has_results":false},{"nct_id":"NCT06054295","title":"Somatic Mosaicism in Twins Discordant for Childhood Cancer","phase":"","overall_status":"RECRUITING","enrollment_count":50,"lead_sponsor_name":"Children's Oncology Group","has_results":false},{"nct_id":"NCT03966742","title":"Doxorubicin Eluting Intra-arterial Embolization for Aggressive Desmoid Fibromatosis","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":8,"lead_sponsor_name":"Rabin Medical Center","has_results":false},{"nct_id":"NCT02595840","title":"Biomarker Study Accompanying the AIO-TRK-0114 Study (MARBLE)","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":4,"lead_sponsor_name":"Universität Duisburg-Essen","has_results":false}],"total":17},"guidelines":[],"source":"Drug Landscape verified database"}