{"disease":{"id":"sleep-disorder","name":"sleep disorder"},"drugs":{"marketed":[{"drug_id":"armodafinil","indication_name":"Sleepiness Due To Shift Work Sleep Disorder","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Nuvigil","generic_name":"ARMODAFINIL","company_name":"Nuvo Pharms","drug_phase":"marketed","molecular_target":"D(2) dopamine receptor","drug_class":"armodafinil","quality_score":54,"revenue":null,"mechanism":"Nuvigil works by selectively targeting the D(2) dopamine receptor to increase wakefulness and alertness."},{"drug_id":"modafinil","indication_name":"Sleepiness Due To Shift Work Sleep Disorder","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Provigil","generic_name":"modafinil","company_name":"Nuvo Pharms","drug_phase":"marketed","molecular_target":"D(2) dopamine receptor","drug_class":"Sympathomimetic-like Agent [EPC]","quality_score":80,"revenue":null,"mechanism":"Provigil works by increasing the activity of certain neurotransmitters in the brain, such as dopamine, to help regulate sleep-wake cycles."}],"pipeline":[],"offLabel":[],"totalMarketed":2,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT05247333","title":"Implementation of a Minor Ailment Service in Community Pharmacy Practice","phase":"NA","overall_status":"COMPLETED","enrollment_count":20987,"lead_sponsor_name":"Universidad de Granada","has_results":false},{"nct_id":"NCT06755840","title":"Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort Study","phase":"","overall_status":"RECRUITING","enrollment_count":15000,"lead_sponsor_name":"Xiangya Hospital of Central South University","has_results":false},{"nct_id":"NCT06763549","title":"COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":15000,"lead_sponsor_name":"Peerbridge Health, Inc","has_results":false},{"nct_id":"NCT07339371","title":"Comprehensive Care of Sleep Disordered Breathing","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":11100,"lead_sponsor_name":"Beijing Anzhen Hospital","has_results":false},{"nct_id":"NCT04256720","title":"The Multi-Ethnic Lifestyle Study","phase":"","overall_status":"UNKNOWN","enrollment_count":9500,"lead_sponsor_name":"University of Leicester","has_results":false},{"nct_id":"NCT06760000","title":"S365: A Multicenter Longitudinal Cohort of Sleep Health","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":5000,"lead_sponsor_name":"Peking University","has_results":false},{"nct_id":"NCT05657808","title":"Radicle Rest 2: A Study of Health and Wellness Products on Sleep and Health Outcomes","phase":"NA","overall_status":"COMPLETED","enrollment_count":4152,"lead_sponsor_name":"Radicle Science","has_results":false},{"nct_id":"NCT06336525","title":"Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometabolic Health Disparities.","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":3680,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT06669507","title":"The Sleep Clinic Outcome and Practice Study","phase":"NA","overall_status":"RECRUITING","enrollment_count":3400,"lead_sponsor_name":"St. Olavs Hospital","has_results":false},{"nct_id":"NCT04693182","title":"Health Promoting Work Schedules: The Effect of Abolishing Quick Returns","phase":"NA","overall_status":"UNKNOWN","enrollment_count":2700,"lead_sponsor_name":"Norwegian Institute of Public Health","has_results":false},{"nct_id":"NCT05511818","title":"Radicle Rest: A Study of Cannabinoids on Sleep and Health Outcomes","phase":"NA","overall_status":"COMPLETED","enrollment_count":2679,"lead_sponsor_name":"Radicle Science","has_results":false},{"nct_id":"NCT04519177","title":"Randomized Trial of a Sleep Disorders Program on Firefighter Safety and Disability ...","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":2400,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT03276585","title":"Night in Japan Home Sleep Monitoring Study","phase":"","overall_status":"UNKNOWN","enrollment_count":2000,"lead_sponsor_name":"Shiga University","has_results":false},{"nct_id":"NCT00071786","title":"Family Study of Affective and Anxiety Spectrum Disorders","phase":"","overall_status":"COMPLETED","enrollment_count":1944,"lead_sponsor_name":"National Institute of Mental Health (NIMH)","has_results":false},{"nct_id":"NCT06347744","title":"Radicle Rest 24: A Study of Health and Wellness Products on Sleep and Related Health Outcomes","phase":"NA","overall_status":"COMPLETED","enrollment_count":1646,"lead_sponsor_name":"Radicle Science","has_results":false},{"nct_id":"NCT04399200","title":"Apnea, Stroke and Incident Cardiovascular Events","phase":"","overall_status":"RECRUITING","enrollment_count":1620,"lead_sponsor_name":"University Hospital, Grenoble","has_results":false},{"nct_id":"NCT04598685","title":"Early Vascular Ageing in the YOUth","phase":"","overall_status":"COMPLETED","enrollment_count":1517,"lead_sponsor_name":"VASCage GmbH","has_results":false},{"nct_id":"NCT05656365","title":"Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders","phase":"","overall_status":"RECRUITING","enrollment_count":1500,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":false},{"nct_id":"NCT04224285","title":"Operational Trial of Dayzz App","phase":"NA","overall_status":"COMPLETED","enrollment_count":1355,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT07398430","title":"Metabolic Characteristics and Prognostic Model of Acute Coronary Syndrome Complicated With Obstructive Sleep Apnea","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":1200,"lead_sponsor_name":"Beijing Hospital","has_results":false},{"nct_id":"NCT04641819","title":"Yangzheng Compound Mixture in the Treatment of Sleep Disorder in Cancer Patients","phase":"PHASE4","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":1127,"lead_sponsor_name":"ShuGuang Hospital","has_results":false},{"nct_id":"NCT03855774","title":"Polymorphisms, Caffeine and Sleep Disorders","phase":"NA","overall_status":"COMPLETED","enrollment_count":1100,"lead_sponsor_name":"Institut de Recherche Biomedicale des Armees","has_results":false},{"nct_id":"NCT06441383","title":"Assessment of Sleep Disordersin People Living With HIV in the Era of New Antiretroviral Therapies in North of France","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":1100,"lead_sponsor_name":"Tourcoing Hospital","has_results":false},{"nct_id":"NCT07120711","title":"EGR2 and NLRP3 Pathways in Obstructive Sleep Apnea-Related Cognitive and Mood Disorders","phase":"","overall_status":"RECRUITING","enrollment_count":1000,"lead_sponsor_name":"Xinhua Hospital, Shanghai Jiao Tong University School of Medicine","has_results":false},{"nct_id":"NCT04417153","title":"Who Benefits More? Optimising Mindfulness Based Interventions for Improved Psychological Outcomes","phase":"","overall_status":"UNKNOWN","enrollment_count":1000,"lead_sponsor_name":"National University of Singapore","has_results":false},{"nct_id":"NCT07286877","title":"Enhanced Ward Rounds and Communication for Pre-procedural Anxiety in GI Endoscopy Patients","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":1000,"lead_sponsor_name":"LanZhou University","has_results":false},{"nct_id":"NCT06664944","title":"Technology Exposure and Child Health: Wellness Impact and Social Effects: An Observational Product Registry Study","phase":"","overall_status":"COMPLETED","enrollment_count":912,"lead_sponsor_name":"Aura","has_results":false},{"nct_id":"NCT00819208","title":"Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for High-Risk Stage II or Stage III Colon Cancer","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":889,"lead_sponsor_name":"Canadian Cancer Trials Group","has_results":false},{"nct_id":"NCT04636112","title":"Sleep Habits and AMI and Gensini Score","phase":"","overall_status":"COMPLETED","enrollment_count":873,"lead_sponsor_name":"The First Affiliated Hospital with Nanjing Medical University","has_results":false},{"nct_id":"NCT06744673","title":"A Study to Assess the Pregnancy Outcome in Women Exposed to Dayvigo® During Pregnancy Compared to an Unexposed Control Population","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":861,"lead_sponsor_name":"Eisai Inc.","has_results":false},{"nct_id":"NCT06427265","title":"Machine Learning-based Longitudinal Study of Post-ICU Syndrome Development Trajectory in Critically Ill Patients and Construction of Clinical Early Warning Models: a Research Protocol for Longitudinal Study","phase":"","overall_status":"RECRUITING","enrollment_count":840,"lead_sponsor_name":"The Affiliated Hospital Of Guizhou Medical University","has_results":false},{"nct_id":"NCT06619912","title":"Dexmedetomidine in Reducing Postoperative Delirium in Cardiac Surgery Patients","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":686,"lead_sponsor_name":"Xijing Hospital","has_results":false},{"nct_id":"NCT03763071","title":"Sleep Disturbances in the 2nd and 3rd Trimester","phase":"","overall_status":"COMPLETED","enrollment_count":683,"lead_sponsor_name":"Bartin State Hospital","has_results":false},{"nct_id":"NCT07444372","title":"Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation Ablation","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":658,"lead_sponsor_name":"Beijing Anzhen Hospital","has_results":false},{"nct_id":"NCT05171725","title":"Multidisciplinary Expert System for the Assessment & Management of Complex Brain Disorders","phase":"","overall_status":"COMPLETED","enrollment_count":635,"lead_sponsor_name":"Neurological Institute of Athens","has_results":false},{"nct_id":"NCT03903263","title":"Sleep Disturbances in Dermatology Patients","phase":"","overall_status":"COMPLETED","enrollment_count":624,"lead_sponsor_name":"University Hospital, Basel, Switzerland","has_results":false},{"nct_id":"NCT03614377","title":"DEvice-Detected CArdiac Tachyarrhythmic Events and Sleep-disordered Breathing (DEDiCATES)","phase":"","overall_status":"UNKNOWN","enrollment_count":600,"lead_sponsor_name":"Samsung Medical Center","has_results":false},{"nct_id":"NCT06140511","title":"DREAMER - IsolateD REM Sleep Without Atonia as a Risk Factor for REM Sleep Behavior disordER","phase":"","overall_status":"UNKNOWN","enrollment_count":600,"lead_sponsor_name":"Oasi Research Institute-IRCCS","has_results":false},{"nct_id":"NCT06093633","title":"A Prospective Study to Evaluate the WP in Comparison to PSG in Patients Suspected of Sleep Disorders","phase":"","overall_status":"RECRUITING","enrollment_count":600,"lead_sponsor_name":"Itamar-Medical, Israel","has_results":false},{"nct_id":"NCT06242717","title":"Postpartum Screening for Anxiety and Comorbid Conditions","phase":"","overall_status":"UNKNOWN","enrollment_count":550,"lead_sponsor_name":"University of British Columbia","has_results":false},{"nct_id":"NCT04573556","title":"A Study to Evaluate the Safety of DAYVIGO (Lemborexant) Tablets in Participants With Insomnia.","phase":"","overall_status":"COMPLETED","enrollment_count":550,"lead_sponsor_name":"Eisai Co., Ltd.","has_results":false},{"nct_id":"NCT00561821","title":"Efficacy and Safety Study of Org 50081 (Esmirtazapine) in Elderly Participants (P05709)","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":538,"lead_sponsor_name":"Merck Sharp & Dohme LLC","has_results":true},{"nct_id":"NCT06070389","title":"Polysomnography Validation of the Sansa Device","phase":"NA","overall_status":"COMPLETED","enrollment_count":533,"lead_sponsor_name":"Huxley Medical, Inc.","has_results":false},{"nct_id":"NCT06367400","title":"Validation of Pediatric Sleep Questionnaire on a Swedish Cohort","phase":"","overall_status":"RECRUITING","enrollment_count":520,"lead_sponsor_name":"Uppsala University","has_results":false},{"nct_id":"NCT03026634","title":"Prevalence and Dynamic of Sleep-disordered Breathing in Patients Pre and Post Heart Transplantation","phase":"","overall_status":"COMPLETED","enrollment_count":500,"lead_sponsor_name":"Heart and Diabetes Center North-Rhine Westfalia","has_results":false},{"nct_id":"NCT05359302","title":"Effects of Ramadan Fasting on Sleeping and Quality of Life","phase":"","overall_status":"COMPLETED","enrollment_count":500,"lead_sponsor_name":"University of Monastir","has_results":false},{"nct_id":"NCT05321355","title":"Mainz Register of Patients With Sleep Disorders","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Johannes Gutenberg University Mainz","has_results":false},{"nct_id":"NCT03623672","title":"North American Prodromal Synucleinopathy Consortium","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":500,"lead_sponsor_name":"Washington University School of Medicine","has_results":false},{"nct_id":"NCT05336890","title":"Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Ann & Robert H Lurie Children's Hospital of Chicago","has_results":false},{"nct_id":"NCT05826457","title":"North American Prodromal Synucleinopathy Consortium Stage 2","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Washington University School of Medicine","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}