{"disease":{"id":"skin-ulcer","name":"Skin ulcer","therapeutic_area":"","data":{},"enrichment_level":0,"last_enriched_at":null,"visit_count":0,"created_at":"2026-04-19T18:31:21.150Z","updated_at":"2026-04-19T18:39:44.960Z","meddra_pt":null,"meddra_code":null,"icd10_codes":null,"synonyms":[],"prevalence_global":null,"prevalence_us":null,"marketed_drug_count":3,"pipeline_drug_count":0,"trial_count":0},"drugs":{"marketed":[{"drug_id":"sodium-hypochlorite","indication_name":"Treat cuts, abrasions, and skin ulcers","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"SODIUM HYPOCHLORITE","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"sodium hypochlorite","quality_score":16,"revenue":null,"mechanism":""},{"drug_id":"sulfadiazine","indication_name":"Skin ulcer","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Sulfadiazine","generic_name":"SULFADIAZINE","company_name":"Eli Lilly","drug_phase":"marketed","molecular_target":"5-hydroxytryptamine receptor 2A","drug_class":"Sulfonamide Antibacterial [EPC]","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"acexamic-acid","indication_name":"Skin ulcer","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Acemin","generic_name":"ACEXAMIC ACID","company_name":"","drug_phase":"phase_3","molecular_target":"","drug_class":"","quality_score":15,"revenue":null,"mechanism":"Acemin works by interacting with specific biological pathways to promote healing in skin ulcers."},{"drug_id":"advanced-therapy-only-without-dietary-intervention","indication_name":"Cultured Autologous Tissue-Engineered Skin Substitute for the Treatment of Ulcerative Colitis","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Advanced therapy only without dietary intervention","generic_name":"advanced-therapy-only-without-dietary-intervention","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"various cell types","drug_class":"advanced therapy","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"advanced-therapy-only-without-dietary-intervention","indication_name":"Cultured Autologous Tissue-Engineered Skin Substitute for the Treatment of Wound Healing in Venous Ulcer Patients","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Advanced therapy only without dietary intervention","generic_name":"advanced-therapy-only-without-dietary-intervention","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"various cell types","drug_class":"advanced therapy","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"advanced-therapy-only-without-dietary-intervention","indication_name":"Cultured Autologous Tissue-Engineered Skin Substitute for the Treatment of Wound Healing in Wound Care in Venous Ulcer Patients","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Advanced therapy only without dietary intervention","generic_name":"advanced-therapy-only-without-dietary-intervention","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"various cell types","drug_class":"advanced therapy","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"advanced-therapy-only-without-dietary-intervention","indication_name":"Cultured Autologous Tissue-Engineered Skin Substitute for the Treatment of Wound Healing in Wound Care in Wound Care in Venous Ulcer Patients","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Advanced therapy only without dietary intervention","generic_name":"advanced-therapy-only-without-dietary-intervention","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"various cell types","drug_class":"advanced therapy","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"advanced-therapy-only-without-dietary-intervention","indication_name":"Cultured Autologous Tissue-Engineered Skin Substitute for the Treatment of Wound Healing in Wound Care in Wound Care in Wound Care in Venous Ulcer Patients","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Advanced therapy only without dietary intervention","generic_name":"advanced-therapy-only-without-dietary-intervention","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"various cell types","drug_class":"advanced therapy","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"advanced-therapy-only-without-dietary-intervention","indication_name":"Cultured Autologous Tissue-Engineered Skin Substitute for the Treatment of Wound Healing in Wound Care in Wound Care in Wound Care in Wound Care in Venous Ulcer Patients","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Advanced therapy only without dietary intervention","generic_name":"advanced-therapy-only-without-dietary-intervention","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"various cell types","drug_class":"advanced therapy","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"advanced-therapy-only-without-dietary-intervention","indication_name":"Cultured Autologous Tissue-Engineered Skin Substitute for the Treatment of Wound Healing in Wound Care in Wound Care in Wound Care in Wound Care in Wound Care in Venous Ulcer Patients","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Advanced therapy only without dietary intervention","generic_name":"advanced-therapy-only-without-dietary-intervention","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"various cell types","drug_class":"advanced therapy","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"silvadene","indication_name":"Skin ulcer","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Silvadene","generic_name":"Silver Sulfadiazine","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"bacterial cell membrane and cell wall","drug_class":"sulfonamide antimicrobial","quality_score":10,"revenue":null,"mechanism":"Silver sulfadiazine acts on bacterial cell membrane and cell wall to produce bactericidal effect."}],"pipeline":[],"offLabel":[],"totalMarketed":11,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT03957447","title":"Treat Early and Broad: Thermotherapy of Buruli Ulcer Integrated Into WHO-recommended Wound Management in West Africa","phase":"","overall_status":"UNKNOWN","enrollment_count":5000,"lead_sponsor_name":"University Hospital Heidelberg","has_results":false},{"nct_id":"NCT06583395","title":"Quest to Analyze One Thousand Humans Meditating","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":3000,"lead_sponsor_name":"Tobias Moeller-Bertram","has_results":false},{"nct_id":"NCT07506967","title":"Early Detection and AI-Based Management of Skin-Related Neglected Tropical Diseases in Sub-Saharan Africa by Frontline Health Workers","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":2420,"lead_sponsor_name":"Kenya Medical Research Institute","has_results":false},{"nct_id":"NCT06369688","title":"IDEAL SKIIN CARES Bundle to Prevent Pressure Injury","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":1620,"lead_sponsor_name":"Baqiyatallah Medical Sciences University","has_results":false},{"nct_id":"NCT06167226","title":"Understanding Ayurveda Disease Conditions and Treatment Responses","phase":"","overall_status":"COMPLETED","enrollment_count":497,"lead_sponsor_name":"Ayurai Private Limited","has_results":false},{"nct_id":"NCT03823963","title":"Study on Pressure Ulcers Prevention With Mepilex® Border Sacrum Dressing in Scheduled Cardiovascular Surgery","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":478,"lead_sponsor_name":"University Hospital, Clermont-Ferrand","has_results":false},{"nct_id":"NCT03824886","title":"Enhancing SKIN Health and Safety in Aged CARE","phase":"NA","overall_status":"COMPLETED","enrollment_count":405,"lead_sponsor_name":"PD Dr. Jan Kottner","has_results":false},{"nct_id":"NCT03445975","title":"Washcloths Effectiveness in Preventing Pressure Ulcers","phase":"NA","overall_status":"COMPLETED","enrollment_count":240,"lead_sponsor_name":"Ospedale San Donato","has_results":false},{"nct_id":"NCT07350811","title":"Retrospective, Observationnal Study to Investigate Procedural Analgesia Delivered to Patients With Lacerations, Abrasions, Burns and Leg Ulcers.","phase":"","overall_status":"COMPLETED","enrollment_count":240,"lead_sponsor_name":"Versailles Hospital","has_results":false},{"nct_id":"NCT06674980","title":"Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs","phase":"NA","overall_status":"RECRUITING","enrollment_count":177,"lead_sponsor_name":"C5 Biomedical","has_results":false},{"nct_id":"NCT04971161","title":"Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of CVU (Phase IIb)","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":159,"lead_sponsor_name":"RHEACELL GmbH & Co. KG","has_results":false},{"nct_id":"NCT07079774","title":"TrueLok Elevate PMCF Study","phase":"","overall_status":"RECRUITING","enrollment_count":153,"lead_sponsor_name":"Orthofix s.r.l.","has_results":false},{"nct_id":"NCT06873867","title":"Treatment of Full-Thickness Wounds: NPWT Combined With Type-I Collagen Based Advanced Skin Substitute Versus NPWT Alone","phase":"NA","overall_status":"COMPLETED","enrollment_count":104,"lead_sponsor_name":"Adichunchanagiri Institute of Medical Sciences, B G Nagara","has_results":true},{"nct_id":"NCT07420868","title":"Comparison of Platelet-Rich Plasma Dressing Versus Normal Saline Dressing for Chronic Non-Healing Ulcers","phase":"NA","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"Multan Medical And Dental College","has_results":false},{"nct_id":"NCT06790277","title":"Polyurethane Foam-Pink Pad (RCT) Use in OR","phase":"NA","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"King Abdullah Medical City","has_results":false},{"nct_id":"NCT05729334","title":"Clinical Investigation EUCLIDES-01 for the Calculation of the Area of Skin Lesions","phase":"NA","overall_status":"COMPLETED","enrollment_count":65,"lead_sponsor_name":"Skilled Skin S.L.","has_results":false},{"nct_id":"NCT04065594","title":"Platelet Rich Plasma (PRP) Bio Stimulant Gel Dressing in Treating Chronic Non Healing Leg and Foot Ulcers: Cost and Effectiveness","phase":"NA","overall_status":"COMPLETED","enrollment_count":44,"lead_sponsor_name":"Zagazig University","has_results":false},{"nct_id":"NCT05378997","title":"Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa.","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":35,"lead_sponsor_name":"Xinnate AB","has_results":false},{"nct_id":"NCT03257098","title":"Allogeneic ABCB5-positive Stem Cells for Treatment of CVU","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":31,"lead_sponsor_name":"RHEACELL GmbH & Co. KG","has_results":false},{"nct_id":"NCT04689243","title":"Low Concentration ALA-PDT in Treatment of Skin Ulcer","phase":"NA","overall_status":"UNKNOWN","enrollment_count":28,"lead_sponsor_name":"Sichuan Provincial People's Hospital","has_results":false},{"nct_id":"NCT06425068","title":"Assessment of an Innovative Air Mattress on Critically Ill Infants","phase":"NA","overall_status":"COMPLETED","enrollment_count":23,"lead_sponsor_name":"Simon Annaheim","has_results":false},{"nct_id":"NCT05608317","title":"A Clinical Investigation to Follow the Progress of Exuding Chronic Venous Leg Ulcers Using a Non-Bordered Foam Dressing","phase":"NA","overall_status":"RECRUITING","enrollment_count":20,"lead_sponsor_name":"Molnlycke Health Care AB","has_results":false},{"nct_id":"NCT06563323","title":"Guselkumab in the Treatment of Adults With Pyoderma Gangrenosum (PG)","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":17,"lead_sponsor_name":"Oregon Health and Science University","has_results":false},{"nct_id":"NCT04145154","title":"Plasma and Scarring of Diabetic Ulcers","phase":"NA","overall_status":"COMPLETED","enrollment_count":16,"lead_sponsor_name":"Universidad de Guanajuato","has_results":false},{"nct_id":"NCT07428954","title":"Using Artificial Intelligence to Help Doctors Identify Different Skin Conditions and Improve Patient Care","phase":"","overall_status":"COMPLETED","enrollment_count":16,"lead_sponsor_name":"AI Labs Group S.L","has_results":false},{"nct_id":"NCT04577183","title":"A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1","phase":"NA","overall_status":"TERMINATED","enrollment_count":13,"lead_sponsor_name":"RedDress Ltd.","has_results":true},{"nct_id":"NCT07016438","title":"Clinical Study of PAL-222 Targeting Patients With Refractory Skin Ulcer","phase":"NA","overall_status":"RECRUITING","enrollment_count":6,"lead_sponsor_name":"PharmaBio Corporation","has_results":false},{"nct_id":"NCT04901325","title":"Baricitinib in the Treatment of Adults With Pyoderma Gangrenosum (PG)","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":5,"lead_sponsor_name":"Oregon Health and Science University","has_results":false},{"nct_id":"NCT01657318","title":"Olivamine-containing Products in the Management of Patients With Nonhealing Lower Extremity Ulcers","phase":"","overall_status":"TERMINATED","enrollment_count":5,"lead_sponsor_name":"De La Salle University Medical Center","has_results":false},{"nct_id":"NCT04240574","title":"Debritom - Micro Water Jet Technology and Wound Healing","phase":"NA","overall_status":"TERMINATED","enrollment_count":2,"lead_sponsor_name":"Stephanie Wu","has_results":true}],"total":30},"guidelines":[],"source":"Drug Landscape verified database"}