{"disease":{"id":"shame","name":"shame","therapeutic_area":"","data":{},"enrichment_level":0,"last_enriched_at":null,"visit_count":0,"created_at":"2026-04-19T18:31:21.150Z","updated_at":"2026-04-19T18:39:44.960Z","meddra_pt":null,"meddra_code":null,"icd10_codes":null,"synonyms":[],"prevalence_global":null,"prevalence_us":null,"marketed_drug_count":1,"pipeline_drug_count":0,"trial_count":0},"drugs":{"marketed":[{"drug_id":"serotonin","indication_name":"shame","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Shame","generic_name":"SEROTONIN","company_name":"Deseret Biologicals, Inc.","drug_phase":"marketed","molecular_target":"","drug_class":"Non-Standardized Fungal Allergenic Extract [EPC]","quality_score":16,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":1,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04600557","title":"A Compassion-based Intervention for Internal and External Shame","phase":"NA","overall_status":"COMPLETED","enrollment_count":439,"lead_sponsor_name":"University of Texas at Austin","has_results":false},{"nct_id":"NCT05475535","title":"Can a Self-guided Mobile Phone Application Program Improve Wellbeing in University Students","phase":"NA","overall_status":"UNKNOWN","enrollment_count":400,"lead_sponsor_name":"National University of Singapore","has_results":false},{"nct_id":"NCT03504605","title":"Impact of Parental Perfectionistic Cognitions Self-compassion Intervention Effects on Shame in Child Health Context","phase":"NA","overall_status":"COMPLETED","enrollment_count":344,"lead_sponsor_name":"University of Sheffield","has_results":false},{"nct_id":"NCT06110702","title":"Effects of an EMDR Intervention on Traumatic and Obsessive Symptoms","phase":"NA","overall_status":"COMPLETED","enrollment_count":287,"lead_sponsor_name":"University of Pisa","has_results":false},{"nct_id":"NCT07284160","title":"A Study on the Effectiveness of Rest Shame Interventions Based on Cognitive Behavioural Therapy in Reducing Social Media Addiction","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":120,"lead_sponsor_name":"The Fourth Affiliated Hospital of Zhejiang University School of Medicine","has_results":false},{"nct_id":"NCT04243018","title":"Feasibility Trial of an Acceptance and Commitment Therapy Intervention for Individuals Experiencing Homelessness","phase":"NA","overall_status":"COMPLETED","enrollment_count":80,"lead_sponsor_name":"University College Dublin","has_results":false},{"nct_id":"NCT04984252","title":"Testing a Brief and Low Intensity Self-compassion Intervention","phase":"NA","overall_status":"COMPLETED","enrollment_count":69,"lead_sponsor_name":"University of Sheffield","has_results":false},{"nct_id":"NCT07294001","title":"Shame-Focused Cognitive Behavioral Therapy For Reducing Suicide Risk In Adolescent Psychiatric Inpatients (SF-CBT)","phase":"NA","overall_status":"RECRUITING","enrollment_count":42,"lead_sponsor_name":"Peking University","has_results":false},{"nct_id":"NCT05106959","title":"Piloting a Motivational Interviewing Shame-Resilience Training","phase":"NA","overall_status":"COMPLETED","enrollment_count":20,"lead_sponsor_name":"University of New Mexico","has_results":true},{"nct_id":"NCT05044715","title":"Effectiveness of Compassion Focused Therapy (CFT)","phase":"NA","overall_status":"TERMINATED","enrollment_count":14,"lead_sponsor_name":"Brigham Young University","has_results":false},{"nct_id":"NCT03463356","title":"Brief Shame Intervention Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":14,"lead_sponsor_name":"Miami University","has_results":false},{"nct_id":"NCT06384508","title":"Decrease Trauma-related Shame With Virtual Reality: The Effectiveness of SHINE-VR","phase":"NA","overall_status":"COMPLETED","enrollment_count":6,"lead_sponsor_name":"Universiteit Leiden","has_results":false},{"nct_id":"NCT01381146","title":"Victim Impact Modules for Jail Inmates","phase":"NA","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"George Mason University","has_results":false}],"total":13},"guidelines":[],"source":"Drug Landscape verified database"}