{"disease":{"id":"septic-arthritis","name":"septic arthritis"},"drugs":{"marketed":[{"drug_id":"ceftriaxon","indication_name":"E. Coli Septic Arthritis","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Ceftriaxon","company_name":"Centre Hospitalier Universitaire Vaudois","drug_phase":"marketed","molecular_target":"Alpha-synuclein, D-amino-acid oxidase, Penicillin-binding protein 1A","drug_class":"","quality_score":19,"revenue":null,"mechanism":null},{"drug_id":"ceftriaxon","indication_name":"Haemophilus Septic Arthritis","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Ceftriaxon","company_name":"Centre Hospitalier Universitaire Vaudois","drug_phase":"marketed","molecular_target":"Alpha-synuclein, D-amino-acid oxidase, Penicillin-binding protein 1A","drug_class":"","quality_score":19,"revenue":null,"mechanism":null},{"drug_id":"ceftriaxone","indication_name":"E. Coli Septic Arthritis","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Rocephin","generic_name":"ceftriaxone","company_name":"Generic (originally Roche)","drug_phase":"marketed","molecular_target":"Alpha-synuclein, D-amino-acid oxidase, Penicillin-binding protein 1A","drug_class":"Cephalosporin antibiotic (third-generation)","quality_score":50,"revenue":null,"mechanism":""},{"drug_id":"ceftriaxone","indication_name":"Haemophilus Septic Arthritis","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Rocephin","generic_name":"ceftriaxone","company_name":"Generic (originally Roche)","drug_phase":"marketed","molecular_target":"Alpha-synuclein, D-amino-acid oxidase, Penicillin-binding protein 1A","drug_class":"Cephalosporin antibiotic (third-generation)","quality_score":50,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":4,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06630988","title":"Diagnostic and Management of Hand Infection.","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":1400,"lead_sponsor_name":"Hospices Civils de Lyon","has_results":false},{"nct_id":"NCT05341908","title":"Prevalence of Pathogens in Synovial Fluid Obtained From Emergency Department Patients","phase":"","overall_status":"COMPLETED","enrollment_count":750,"lead_sponsor_name":"Olive View-UCLA Education & Research Institute","has_results":false},{"nct_id":"NCT05790434","title":"Diagnostic Criteria for Septic Arthritis","phase":"","overall_status":"UNKNOWN","enrollment_count":400,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT03716921","title":"Short 3-week Antibiotic Treatment Versus 6 Weeks in Adults With Septic Arthritis of Native Joint","phase":"NA","overall_status":"COMPLETED","enrollment_count":332,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT03979937","title":"Development and Validation of a Simple Diagnostic Tool Predictive of the Aseptic Character of Joint Effusion","phase":"","overall_status":"COMPLETED","enrollment_count":328,"lead_sponsor_name":"Centre Hospitalier le Mans","has_results":false},{"nct_id":"NCT04141787","title":"Ceftriaxone as Home IV for Staph Infections","phase":"PHASE4","overall_status":"UNKNOWN","enrollment_count":310,"lead_sponsor_name":"Vancouver Island Health Authority","has_results":false},{"nct_id":"NCT04460144","title":"Rapid Diagnostic Test for Septic Arthritis","phase":"","overall_status":"COMPLETED","enrollment_count":274,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT04284423","title":"Study of Synovial Lactate Level as Marker of Septic Arthritis","phase":"","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Khoo Teck Puat Hospital","has_results":false},{"nct_id":"NCT04563325","title":"Oral-only Antibiotics for Bone and Joint Infections in Children","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":180,"lead_sponsor_name":"Rigshospitalet, Denmark","has_results":false},{"nct_id":"NCT05971745","title":"Accuracy of Pediatric Emergency Medicine Providers in Diagnosing Hip Effusions Using Point of Care Ultrasound","phase":"","overall_status":"COMPLETED","enrollment_count":161,"lead_sponsor_name":"Connecticut Children's Medical Center","has_results":false},{"nct_id":"NCT03827759","title":"Differentiate Children Septic and Inflammatory Arthritis by Comparative Analysis","phase":"","overall_status":"TERMINATED","enrollment_count":100,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT06241365","title":"The Predictive Role of C-reactive Protein to Albumin Ratio (CAR) in the Treatment of Septic Arthritis in Young Chlidren","phase":"","overall_status":"COMPLETED","enrollment_count":82,"lead_sponsor_name":"wangxiaodong","has_results":false},{"nct_id":"NCT03827980","title":"Long- and Midterm Outcomes of Osteoarticular Infections in Paediatric Patients","phase":"","overall_status":"COMPLETED","enrollment_count":78,"lead_sponsor_name":"Prof. Dr. Ulrich Heininger","has_results":false},{"nct_id":"NCT00503438","title":"Ankle Joint Replacement Outcomes Study","phase":"","overall_status":"COMPLETED","enrollment_count":76,"lead_sponsor_name":"Smith & Nephew, Inc.","has_results":false},{"nct_id":"NCT06003374","title":"Extended Hip Ultrasound as Anew Protocol for Septic Hip in Children","phase":"","overall_status":"UNKNOWN","enrollment_count":46,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT03426761","title":"Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":41,"lead_sponsor_name":"Infectious Diseases Physicians, Inc.","has_results":false},{"nct_id":"NCT03846804","title":"Next-Generation Sequencing for Pathogen Detection and Quantification in Children With Musculoskeletal Infections","phase":"NA","overall_status":"COMPLETED","enrollment_count":38,"lead_sponsor_name":"Indiana University","has_results":true},{"nct_id":"NCT07388017","title":"Infrared Thermography for Diagnosis of Musculoskeletal Infections","phase":"","overall_status":"RECRUITING","enrollment_count":30,"lead_sponsor_name":"Sheffield Children's NHS Foundation Trust","has_results":false},{"nct_id":"NCT05593874","title":"Predictive Value of Nu.Q™ Biomarkers to Help Guiding the Management of Osteoarticular Infections","phase":"","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"University Hospital, Geneva","has_results":false},{"nct_id":"NCT07321418","title":"Mid-term Results of Epiphyseal Transfer for Hip Post Septic Epiphyseal Loss","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":20,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT07426471","title":"Delafloxacin Plasma and Tissue Concentration in Patients With Skin, Soft Tissue, and Bone and Joint Infections.","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":20,"lead_sponsor_name":"IRCCS San Raffaele","has_results":false},{"nct_id":"NCT03802552","title":"Cefadroxil and Cephalexin Drug Levels and Dosing in Pediatric Musculoskeletal Infections","phase":"PHASE1","overall_status":"COMPLETED","enrollment_count":17,"lead_sponsor_name":"University of Colorado, Denver","has_results":false},{"nct_id":"NCT05484284","title":"Two-stage Arthroplasty for the Septic Arthritis of the Native Knee Joint","phase":"NA","overall_status":"COMPLETED","enrollment_count":14,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT04786379","title":"Surgical Management of Knee Septic Arthritis","phase":"NA","overall_status":"TERMINATED","enrollment_count":10,"lead_sponsor_name":"Texas Tech University Health Sciences Center, El Paso","has_results":false},{"nct_id":"NCT05521880","title":"Anchoring Sequential Intermittent Long Acting Antimicrobials With Medication for Opioid Use Disorder (MOUD) for Invasive Infections Related to Opioid Use","phase":"PHASE4","overall_status":"TERMINATED","enrollment_count":2,"lead_sponsor_name":"University of Maryland, Baltimore","has_results":false},{"nct_id":"NCT05886166","title":"Clinical Utility of Exoskeleton Robot Training in Patients With Septic Arthritis After a Thermal Injury: A Case Report","phase":"NA","overall_status":"UNKNOWN","enrollment_count":2,"lead_sponsor_name":"Hangang Sacred Heart Hospital","has_results":false},{"nct_id":"NCT02508584","title":"Personalized Immunotherapeutic for Antibiotic-resistant Infection","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":1,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false}],"total":27},"guidelines":[],"source":"Drug Landscape verified database"}