{"disease":{"id":"sepsis-septic-shock","name":"sepsis septic shock"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06368336","title":"Health Related Quality of Life After Intensive Care for Sepsis, a National Cohort Study.","phase":"","overall_status":"COMPLETED","enrollment_count":210484,"lead_sponsor_name":"Uppsala University Hospital","has_results":false},{"nct_id":"NCT06354452","title":"Effect of Statin Therapy on Sepsis-related Mortality in Intensive Care Unit Patients","phase":"","overall_status":"COMPLETED","enrollment_count":59578,"lead_sponsor_name":"Hospital de Granollers","has_results":false},{"nct_id":"NCT03752489","title":"Unsupervised Machine Learning for Clustering of Septic Patients to Determine Optimal Treatment","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":51645,"lead_sponsor_name":"Dascena","has_results":false},{"nct_id":"NCT05304728","title":"Sepsis Clinical Decision Support [CDS] Master Enrollment Study Protocol","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":40000,"lead_sponsor_name":"Beckman Coulter, Inc.","has_results":false},{"nct_id":"NCT04005001","title":"Machine Learning Sepsis Alert Notification Using Clinical Data","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":37986,"lead_sponsor_name":"Dascena","has_results":false},{"nct_id":"NCT03655626","title":"Implementation and Evaluations of Sepsis Watch","phase":"NA","overall_status":"COMPLETED","enrollment_count":32003,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT02389036","title":"Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":20010,"lead_sponsor_name":"The George Institute","has_results":false},{"nct_id":"NCT07167173","title":"Predictive Model for Multidrug Resistance in Patients Admitted to the Emergency Department With Sepsis","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Hospital Italiano de Buenos Aires","has_results":false},{"nct_id":"NCT05491941","title":"Assessment for Implementation Methods in Sepsis","phase":"NA","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Rhode Island Hospital","has_results":false},{"nct_id":"NCT04567433","title":"Days Alive and Out of Hospital for Patients With Sepsis","phase":"","overall_status":"COMPLETED","enrollment_count":6213,"lead_sponsor_name":"The George Institute for Global Health, Australia","has_results":false},{"nct_id":"NCT06184659","title":"Empirical Meropenem Versus Piperacillin/Tazobactam for Adult Patients With Sepsis","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":5800,"lead_sponsor_name":"Scandinavian Critical Care Trials Group","has_results":false},{"nct_id":"NCT04903405","title":"Immune Function Monitoring and Immunotherapy in Sepsis","phase":"","overall_status":"UNKNOWN","enrollment_count":5000,"lead_sponsor_name":"Sun Yat-sen University","has_results":false},{"nct_id":"NCT06178822","title":"Towards Novel BIOmarkers to Diagnose SEPsis on the Emergency Room","phase":"","overall_status":"RECRUITING","enrollment_count":3300,"lead_sponsor_name":"Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)","has_results":false},{"nct_id":"NCT05172479","title":"Prognostic Accuracy of qSOFA, SIRS, and EWSs for In-hospital Mortality in Emergency Department","phase":"","overall_status":"COMPLETED","enrollment_count":3274,"lead_sponsor_name":"Aseer Central Hospital","has_results":false},{"nct_id":"NCT03235193","title":"Predictive algoRithm for EValuation and Intervention in SEpsis","phase":"NA","overall_status":"COMPLETED","enrollment_count":2296,"lead_sponsor_name":"Dascena","has_results":false},{"nct_id":"NCT03068741","title":"Paramedic Initiated Treatment of Sepsis Targeting Out-of-hospital Patients (PITSTOP)","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":2061,"lead_sponsor_name":"Dr. Damon Scales","has_results":false},{"nct_id":"NCT04103203","title":"Fast Assay for Pathogen Identification - Quasi-Experimental Intervention Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":1978,"lead_sponsor_name":"Hasselt University","has_results":false},{"nct_id":"NCT03841162","title":"Fast Assay for Pathogen Identification and Characterization","phase":"","overall_status":"COMPLETED","enrollment_count":1957,"lead_sponsor_name":"Hasselt University","has_results":false},{"nct_id":"NCT04203979","title":"Sepsis: From Syndrome to Personalized Care","phase":"","overall_status":"RECRUITING","enrollment_count":1950,"lead_sponsor_name":"Oslo University Hospital","has_results":false},{"nct_id":"NCT03249246","title":"Epidemiology of Sepsis in Turkish ICUs.","phase":"","overall_status":"COMPLETED","enrollment_count":1499,"lead_sponsor_name":"Nur Baykara","has_results":false},{"nct_id":"NCT05065333","title":"Implementation Trial of Predictive Modeling to Enhance Diagnosis and Improve Treatment in Pediatric Septic Shock","phase":"NA","overall_status":"COMPLETED","enrollment_count":1345,"lead_sponsor_name":"University of Colorado, Denver","has_results":false},{"nct_id":"NCT02232750","title":"Evaluation of CPD MNV as an Aid in the Diagnosis and Risk Assessment of Sepsis (Protocol # Sepsis 1-14)","phase":"","overall_status":"COMPLETED","enrollment_count":1320,"lead_sponsor_name":"Ohio State University","has_results":false},{"nct_id":"NCT03077672","title":"Mitochondrial DNA as a Biomarker of Sepsis Severity","phase":"","overall_status":"COMPLETED","enrollment_count":1304,"lead_sponsor_name":"Weill Medical College of Cornell University","has_results":false},{"nct_id":"NCT07369206","title":"ICU Admission Diagnoses and ICU Mortality","phase":"","overall_status":"COMPLETED","enrollment_count":1248,"lead_sponsor_name":"Ataturk University","has_results":false},{"nct_id":"NCT03677102","title":"Fluids in Septic Shock (FISSH)","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":1113,"lead_sponsor_name":"McMaster University","has_results":false},{"nct_id":"NCT05190861","title":"Evaluation of Droplet Digital PCR Rapid Detection Method and Precise Diagnosis and Treatment for Suspected Sepsis","phase":"NA","overall_status":"COMPLETED","enrollment_count":1032,"lead_sponsor_name":"Huashan Hospital","has_results":false},{"nct_id":"NCT06766461","title":"Beta-Lactam Antibiotics InitiaL ExpoSure OptimisEd in CriticallY Ill Patients with SEpsis","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":980,"lead_sponsor_name":"Erasmus Medical Center","has_results":false},{"nct_id":"NCT03708796","title":"DIAGNOSis of Infection in Emergency Department","phase":"","overall_status":"COMPLETED","enrollment_count":759,"lead_sponsor_name":"Association pour la Formation l'Enseignement et la Recherche du Service de l'Accueil des Urgences","has_results":false},{"nct_id":"NCT07179276","title":"Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock","phase":"NA","overall_status":"RECRUITING","enrollment_count":750,"lead_sponsor_name":"University Hospital, Clermont-Ferrand","has_results":false},{"nct_id":"NCT06654895","title":"Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study","phase":"","overall_status":"RECRUITING","enrollment_count":700,"lead_sponsor_name":"Bluejay Diagnostics, Inc.","has_results":false},{"nct_id":"NCT06902493","title":"Impact of Prior SGLT2 Inhibitors Use on the Development and Progression of Sepsis-Associated Acute Kidney Injury","phase":"","overall_status":"COMPLETED","enrollment_count":664,"lead_sponsor_name":"University of Jazan","has_results":false},{"nct_id":"NCT06657625","title":"Impact of the Introduction of a Performance Improvement Program on the Initial Management of Sepsis and Septic Shock in Adults in the Emergency Department: a Before-and-after Study (IPA-SOS)","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":600,"lead_sponsor_name":"University Hospital, Brest","has_results":false},{"nct_id":"NCT03113721","title":"Assessment of Heparin Binding Protein for the Prediction of Severe Sepsis","phase":"","overall_status":"UNKNOWN","enrollment_count":571,"lead_sponsor_name":"Axis Shield Diagnostics Ltd","has_results":false},{"nct_id":"NCT03388944","title":"PCT Guided Stopping of Antibiotic Therapy in Children With Sepsis","phase":"NA","overall_status":"COMPLETED","enrollment_count":561,"lead_sponsor_name":"All India Institute of Medical Sciences","has_results":false},{"nct_id":"NCT03727243","title":"Molecular Diagnosis and Risk Stratification of Sepsis in India","phase":"","overall_status":"UNKNOWN","enrollment_count":550,"lead_sponsor_name":"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","has_results":false},{"nct_id":"NCT03977688","title":"Evaluating a CytoSorb Score in Septic Shock","phase":"","overall_status":"COMPLETED","enrollment_count":500,"lead_sponsor_name":"Klinikum Emden","has_results":false},{"nct_id":"NCT03356249","title":"Next-Generation Sequencing Diagnostics of Bacteremia in Sepsis","phase":"","overall_status":"COMPLETED","enrollment_count":500,"lead_sponsor_name":"University Hospital Heidelberg","has_results":false},{"nct_id":"NCT06287684","title":"Molecular Subtype-Specific Mechanisms and Therapeutic Strategies in Sepsis","phase":"","overall_status":"RECRUITING","enrollment_count":460,"lead_sponsor_name":"Mater Dei Hospital, Malta","has_results":false},{"nct_id":"NCT07425587","title":"Multicenter Symphony™ IL-6 Monitoring Sepsis ED Pilot Study","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":450,"lead_sponsor_name":"Bluejay Diagnostics, Inc.","has_results":false},{"nct_id":"NCT04621981","title":"Sodium Bicarbonate Ringer's Solution Versus Normal Saline for Early Fluid Resuscitation in Patients With Sepsis","phase":"NA","overall_status":"UNKNOWN","enrollment_count":450,"lead_sponsor_name":"Xiangya Hospital of Central South University","has_results":false},{"nct_id":"NCT04571801","title":"Optimization of Sepsis Therapy Based on Patient-specific Digital Precision Diagnostics","phase":"NA","overall_status":"COMPLETED","enrollment_count":410,"lead_sponsor_name":"University Hospital, Essen","has_results":false},{"nct_id":"NCT05787184","title":"Sepsis Early EvaluatioN Through Rapid Ultrasound and veNous Gas Analysis","phase":"","overall_status":"UNKNOWN","enrollment_count":400,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false},{"nct_id":"NCT07442032","title":"Cardiovascular Phenotypes in Sepsis","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":400,"lead_sponsor_name":"Karolinska Institutet","has_results":false},{"nct_id":"NCT02473263","title":"Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":398,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT04316884","title":"Mechanisms for Organ Dysfunction in Covid-19","phase":"","overall_status":"COMPLETED","enrollment_count":380,"lead_sponsor_name":"Uppsala University","has_results":false},{"nct_id":"NCT05140213","title":"A STUDY BEFORE/AFTER THE IMPLEMENTATION OF AN ANTI-INFECTIOUS PRESCRIPTION AID","phase":"","overall_status":"COMPLETED","enrollment_count":371,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT02734550","title":"(1,3)-β-D-glucan Based Diagnosis of Invasive Candida Infection in Sepsis","phase":"NA","overall_status":"COMPLETED","enrollment_count":342,"lead_sponsor_name":"Center for Sepsis Control and Care, Germany","has_results":false},{"nct_id":"NCT01867905","title":"Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock","phase":"","overall_status":"COMPLETED","enrollment_count":330,"lead_sponsor_name":"University of British Columbia","has_results":false},{"nct_id":"NCT04747795","title":"Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":301,"lead_sponsor_name":"Universitaire Ziekenhuizen KU Leuven","has_results":false},{"nct_id":"NCT06709573","title":"Early Versus Late Adjunctive Vasopressin in Septic Shock","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"The Cleveland Clinic","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}