{"disease":{"id":"sentinel-lymph-node","name":"sentinel lymph node"},"drugs":{"marketed":[{"drug_id":"fytic-acid","indication_name":"Sentinel lymph node mapping","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Phyliance","generic_name":"fytic acid","company_name":"PDRadiopharma Inc","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":20,"revenue":null,"mechanism":""},{"drug_id":"indocyanine-green","indication_name":"Sentinel lymph node mapping in breast cancer","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Spy Agent Green Kit","generic_name":"INDOCYANINE GREEN","company_name":"Renew Pharms","drug_phase":"marketed","molecular_target":"","drug_class":"Diagnostic Dye","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"indocyanine-green","indication_name":"Sentinel lymph node mapping in malignant melanoma","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Spy Agent Green Kit","generic_name":"INDOCYANINE GREEN","company_name":"Renew Pharms","drug_phase":"marketed","molecular_target":"","drug_class":"Diagnostic Dye","quality_score":40,"revenue":null,"mechanism":""}],"pipeline":[],"offLabel":[],"totalMarketed":3,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04156841","title":"Sentinel Lymph Node Biopsy in Early Breast Cancer: a Real-world Multicenter Cross-sectional Study (CABS001 Study)","phase":"","overall_status":"UNKNOWN","enrollment_count":21000,"lead_sponsor_name":"Xijing Hospital","has_results":false},{"nct_id":"NCT04109079","title":"Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy","phase":"NA","overall_status":"RECRUITING","enrollment_count":1900,"lead_sponsor_name":"University Hospitals of Derby and Burton NHS Foundation Trust","has_results":false},{"nct_id":"NCT04303715","title":"No Axillary sUrgical Treatment In Clinically Lymph Node Negative Patients After UltraSonography","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":1734,"lead_sponsor_name":"Seoul National University Hospital","has_results":false},{"nct_id":"NCT05707312","title":"Staging Endometrial caNcer Based on molEcular ClAssification","phase":"","overall_status":"UNKNOWN","enrollment_count":1032,"lead_sponsor_name":"Clinica Universidad de Navarra, Universidad de Navarra","has_results":false},{"nct_id":"NCT04889924","title":"ALND vs ART in Positive Sentinel Node After Neoadjuvant Therapy in Breast Cancer","phase":"NA","overall_status":"RECRUITING","enrollment_count":820,"lead_sponsor_name":"Hospital Universitari de Bellvitge","has_results":false},{"nct_id":"NCT04276532","title":"Sentinel Lymph Node Sampling for Patients With Middle-high Risk Endometrial Cancer Confined to the Uterus","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":780,"lead_sponsor_name":"Xiaojun Chen","has_results":false},{"nct_id":"NCT06149377","title":"Impact of a Predictive Model on Sentinel Lymph Node Biopsy in Initially Lymph Node-positive, HER2-positive Breast Cancer","phase":"","overall_status":"COMPLETED","enrollment_count":716,"lead_sponsor_name":"Fujian Medical University Union Hospital","has_results":false},{"nct_id":"NCT06911528","title":"Application of EndoScell Intraoperative Cellular Probing Technology for Early-Stage Breast Cancer","phase":"NA","overall_status":"RECRUITING","enrollment_count":709,"lead_sponsor_name":"Fudan University","has_results":false},{"nct_id":"NCT07098507","title":"De-escalation in Axillary Surgery for Early-stage Breast Cancer","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":620,"lead_sponsor_name":"Clinical Hospital Center Rijeka","has_results":false},{"nct_id":"NCT04568941","title":"Comparison Study of Different Tumor Biopsy Method for Sentinel Lymph Node Biopsy in Breast Cancer","phase":"NA","overall_status":"UNKNOWN","enrollment_count":600,"lead_sponsor_name":"Shandong Cancer Hospital and Institute","has_results":false},{"nct_id":"NCT06518135","title":"Axillary Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Patients With Initial cN1 Breast Cancer","phase":"","overall_status":"RECRUITING","enrollment_count":508,"lead_sponsor_name":"Henan Cancer Hospital","has_results":false},{"nct_id":"NCT04250129","title":"SENTINEL LYMPH NODE BIOPSY AFTER NEOADJUVANT CHEMOTHERAPY","phase":"","overall_status":"UNKNOWN","enrollment_count":500,"lead_sponsor_name":"Federation of Breast Diseases Societies","has_results":false},{"nct_id":"NCT04722692","title":"Delayed Sentinel Lymph Node Biopsy in Ductal Cancer in Situ","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"Uppsala University","has_results":false},{"nct_id":"NCT06704945","title":"No Axillary Surgical Treatment in Clinically Lymph Node Negative Patients on Ultrasonography After Neoadjuvant Chemotherapy","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":464,"lead_sponsor_name":"Seoul National University Hospital","has_results":false},{"nct_id":"NCT04932460","title":"Contrast-enhanced Ultrasonography Combined With Blue Dye as Dual-tracer for Sentinel Lymph Node Biopsy","phase":"NA","overall_status":"UNKNOWN","enrollment_count":350,"lead_sponsor_name":"First Affiliated Hospital, Sun Yat-Sen University","has_results":false},{"nct_id":"NCT06259513","title":"Omission of Axillary Surgery in Breast Cancer Patients","phase":"NA","overall_status":"RECRUITING","enrollment_count":350,"lead_sponsor_name":"KK Women's and Children's Hospital","has_results":false},{"nct_id":"NCT06212440","title":"Clinical Application of Multi-modal Sentinel Lymph Node Staining Method in Breast Cancer Patients After Neoadjuvant Chemotherapy","phase":"NA","overall_status":"COMPLETED","enrollment_count":348,"lead_sponsor_name":"National Cancer Center, Korea","has_results":false},{"nct_id":"NCT06652672","title":"Sentinel Node and Organ-sparing Surgery in Stage I Colon Carcinoma","phase":"NA","overall_status":"RECRUITING","enrollment_count":341,"lead_sponsor_name":"Meander Medical Center","has_results":false},{"nct_id":"NCT05048173","title":"Sentinel Lymph Node Biopsy Versus Lymphadenectomy in Endometrial Cancer","phase":"","overall_status":"COMPLETED","enrollment_count":334,"lead_sponsor_name":"Far Eastern Memorial Hospital","has_results":false},{"nct_id":"NCT05935150","title":"Omission of SLNB in CN0 Early Breast Cancer","phase":"NA","overall_status":"RECRUITING","enrollment_count":311,"lead_sponsor_name":"The First Affiliated Hospital with Nanjing Medical University","has_results":false},{"nct_id":"NCT05288686","title":"Use of Superparamagnetic Iron Oxide (SPIO) in Sentinel Lymph Node Detection for Breast Cancer","phase":"NA","overall_status":"UNKNOWN","enrollment_count":282,"lead_sponsor_name":"The University of Hong Kong","has_results":false},{"nct_id":"NCT06673511","title":"The Application of Sentinel Lymph Node Mapping Technique in the Surgery of Early Epithelial Ovarian Cancer","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":246,"lead_sponsor_name":"Anhui Provincial Hospital","has_results":false},{"nct_id":"NCT04829643","title":"Axillary Staging in Early Breast Cancer: SNB vs PET/MRI","phase":"NA","overall_status":"COMPLETED","enrollment_count":246,"lead_sponsor_name":"IRCCS San Raffaele","has_results":false},{"nct_id":"NCT03123042","title":"Feasibility Study of Sentinel Navigation Surgery After Non-curative Endoscopic Resection","phase":"NA","overall_status":"COMPLETED","enrollment_count":243,"lead_sponsor_name":"National Cancer Center, Korea","has_results":false},{"nct_id":"NCT03719833","title":"Sentinel Lymph Node Biopsy After Neoadjuvant Treatment in Breast Cancer Patents","phase":"","overall_status":"COMPLETED","enrollment_count":230,"lead_sponsor_name":"Clinical Hospital Center Rijeka","has_results":false},{"nct_id":"NCT07040540","title":"Hemodynamic Effects of Intradermal Methylene Blue During Breast Surgery Under General Anesthesia","phase":"","overall_status":"COMPLETED","enrollment_count":220,"lead_sponsor_name":"Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital","has_results":false},{"nct_id":"NCT06169072","title":"Sentinel Lymph Node Localisation With an Ultra-low Dose of Magtrace in Breast Cancer Patients","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":220,"lead_sponsor_name":"Vastra Gotaland Region","has_results":false},{"nct_id":"NCT04560491","title":"Intraoperative Examination of Sentinel Node in Endometrial Cancer (TRSGO-SLN-003)","phase":"","overall_status":"COMPLETED","enrollment_count":208,"lead_sponsor_name":"Ankara University","has_results":false},{"nct_id":"NCT05512468","title":"Application of Preoperative Axillary Lymph Node Marking With Nano-Carbon in Breast Cancer Patients Before Neoadjuvant Chemotherapy","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Fujian Medical University Union Hospital","has_results":false},{"nct_id":"NCT04714931","title":"Sentinel Lymph Node Assessment in Ovarian Cancer (TRSGO-SLN-OO5)","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Acibadem University","has_results":false},{"nct_id":"NCT03563781","title":"SEntine Lymph Node in earLY Ovarian Cancer (SELLY)","phase":"NA","overall_status":"COMPLETED","enrollment_count":176,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false},{"nct_id":"NCT07032220","title":"Application of Targeted Axillary Lymph Node Resection in Axillary Surgery After Neoadjuvant Chemotherapy for Breast Cancer: an Open-label, Multicenter Study","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":175,"lead_sponsor_name":"Fujian Medical University Union Hospital","has_results":false},{"nct_id":"NCT04822597","title":"Pain Control for Breast Cancer Patients Receiving Injection of Radioactive Tracer","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":167,"lead_sponsor_name":"University of Wisconsin, Madison","has_results":true},{"nct_id":"NCT05699291","title":"Cost of Using FLUOrescence to Green of Indocyanine for the Detection of Breast Cancer.","phase":"","overall_status":"COMPLETED","enrollment_count":163,"lead_sponsor_name":"GCS Ramsay Santé pour l'Enseignement et la Recherche","has_results":false},{"nct_id":"NCT05763641","title":"TAD After Chemotherapy in Locally Advanced Breast Cancer","phase":"","overall_status":"RECRUITING","enrollment_count":162,"lead_sponsor_name":"Hospital Universitari de Bellvitge","has_results":false},{"nct_id":"NCT05076942","title":"Groningen International Study on Sentinel Nodes in Vulvar Cancer-III","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":157,"lead_sponsor_name":"University Medical Center Groningen","has_results":false},{"nct_id":"NCT03200704","title":"A Study Assessing the Safety and Effectiveness of IC2000 and SPY Fluorescence Imaging Systems (SPY-PHI) in the Visualization of Lymphatic Vessels and Identification of Lymph Nodes During Sentinel Lymph Node Biopsy in Subjects With Breast Cancer","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":152,"lead_sponsor_name":"Novadaq Technologies ULC, now a part of Stryker","has_results":true},{"nct_id":"NCT07303231","title":"The Value of Indocyanine Green-guided Near-infrared Fluorescence Technology in Tracing Sentinel Lymph Nodes During Esophagectomy","phase":"PHASE3","overall_status":"NOT_YET_RECRUITING","enrollment_count":144,"lead_sponsor_name":"Fujian Medical University Union Hospital","has_results":false},{"nct_id":"NCT03606616","title":"Prospective Feasibility Study Applying the ACOSOG Z0011 Criteria to Chinese Patients","phase":"","overall_status":"COMPLETED","enrollment_count":142,"lead_sponsor_name":"Peking University People's Hospital","has_results":false},{"nct_id":"NCT03579979","title":"Sentinel Lymph Node Biopsy in Breast Cancer Surgery Using ICG","phase":"NA","overall_status":"COMPLETED","enrollment_count":130,"lead_sponsor_name":"Chinese Academy of Sciences","has_results":false},{"nct_id":"NCT06412211","title":"A Clinical Feasibility Study of a Photoacoustic Finder","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":129,"lead_sponsor_name":"Seoul St. Mary's Hospital","has_results":false},{"nct_id":"NCT03749707","title":"HPV in Sentinel Lymph Nodes of Cervical Cancer Patients","phase":"NA","overall_status":"COMPLETED","enrollment_count":127,"lead_sponsor_name":"University of Aarhus","has_results":false},{"nct_id":"NCT03549195","title":"TMTP1 Targeting Micro-metastasis LN in Laparoscopic SLN Detection in Cervical Cancer","phase":"NA","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"Huazhong University of Science and Technology","has_results":false},{"nct_id":"NCT06029504","title":"Optical Guided Sentinel Node Biopsy for Staging of Vulvar Cancer (I)","phase":"","overall_status":"RECRUITING","enrollment_count":115,"lead_sponsor_name":"Rigshospitalet, Denmark","has_results":false},{"nct_id":"NCT05985551","title":"Delayed SLND for Patients With Breast Cancer Undergoing Primary Systemic Treatment","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":114,"lead_sponsor_name":"Uppsala University","has_results":false},{"nct_id":"NCT04826211","title":"Axillary Staging in Node Positive Breast Cancer Patients Receiving PST. SNB vs PET/MRI","phase":"NA","overall_status":"COMPLETED","enrollment_count":109,"lead_sponsor_name":"IRCCS San Raffaele","has_results":false},{"nct_id":"NCT04514289","title":"To Assess and Compare the Performance Two Approach for Sentinel Lymph Node (SNLD) Biopsy for Endometrial Cancer","phase":"","overall_status":"UNKNOWN","enrollment_count":106,"lead_sponsor_name":"Haseki Training and Research Hospital","has_results":false},{"nct_id":"NCT04972682","title":"[SENTRY] Tailoring Postoperative Management Through Sentinel Lymph Node Biopsy in Low- and Intermediate-Risk Endometrial Cancer","phase":"NA","overall_status":"COMPLETED","enrollment_count":102,"lead_sponsor_name":"Moscow City Oncology Hospital No. 62","has_results":false},{"nct_id":"NCT03640819","title":"Carbon Dye Tattooing of Biopsied Axillary Node in Breast Cancer","phase":"NA","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"University Hospitals of Derby and Burton NHS Foundation Trust","has_results":false},{"nct_id":"NCT03097575","title":"Bronchial NIR Image-guided Resection","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":100,"lead_sponsor_name":"Massachusetts General Hospital","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}