{"disease":{"id":"sclerosis-systemic","name":"sclerosis systemic"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT07077304","title":"EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":5000,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT05879419","title":"Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases","phase":"PHASE4","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":2005,"lead_sponsor_name":"University of Sao Paulo General Hospital","has_results":false},{"nct_id":"NCT06029335","title":"Clinical Risk Assessment of Cognitive Function in Systemic Autoimmune Diseases","phase":"","overall_status":"UNKNOWN","enrollment_count":400,"lead_sponsor_name":"University of Pecs","has_results":false},{"nct_id":"NCT04781543","title":"A Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":301,"lead_sponsor_name":"Amgen","has_results":true},{"nct_id":"NCT05878717","title":"A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease","phase":"PHASE2, PHASE3","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"GlaxoSmithKline","has_results":false},{"nct_id":"NCT03816345","title":"Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":300,"lead_sponsor_name":"National Cancer Institute (NCI)","has_results":false},{"nct_id":"NCT06462768","title":"Neutrophil Extracellular Traps in Different Forms of Systemic Sclerosis","phase":"","overall_status":"RECRUITING","enrollment_count":260,"lead_sponsor_name":"CHU de Reims","has_results":false},{"nct_id":"NCT05000216","title":"COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":258,"lead_sponsor_name":"National Institute of Allergy and Infectious Diseases (NIAID)","has_results":true},{"nct_id":"NCT06308978","title":"A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":244,"lead_sponsor_name":"Fate Therapeutics","has_results":false},{"nct_id":"NCT05626751","title":"An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc)","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":174,"lead_sponsor_name":"Amgen","has_results":true},{"nct_id":"NCT03819777","title":"Volatile Organic Compounds (VOCs) as a Biomarker in Immune-mediated Pulmonary Arterial Hypertension (PAH)","phase":"","overall_status":"UNKNOWN","enrollment_count":150,"lead_sponsor_name":"Maastricht University Medical Center","has_results":false},{"nct_id":"NCT04927390","title":"Mycophenolate in Limited Cutaneous Systemic Sclerosis (MINIMISE-Pilot)","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":120,"lead_sponsor_name":"University College, London","has_results":false},{"nct_id":"NCT03941184","title":"Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity","phase":"","overall_status":"COMPLETED","enrollment_count":114,"lead_sponsor_name":"Mayo Clinic","has_results":false},{"nct_id":"NCT06287125","title":"Renal Assessment for Early Detection of Renal Impairment in Systemic Sclerosis and Systemic Lupus Erythematosus Patients","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":95,"lead_sponsor_name":"Assiut University","has_results":false},{"nct_id":"NCT06925542","title":"A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":80,"lead_sponsor_name":"CRISPR Therapeutics","has_results":false},{"nct_id":"NCT04746313","title":"Prevalence of Hyperprolactinemia in Systemic Scleroderma","phase":"","overall_status":"COMPLETED","enrollment_count":71,"lead_sponsor_name":"University Hospital, Lille","has_results":false},{"nct_id":"NCT03816189","title":"Role of Eosinophil in Fibrogenesis of Systemic Sclerosis","phase":"","overall_status":"COMPLETED","enrollment_count":70,"lead_sponsor_name":"University Hospital, Lille","has_results":false},{"nct_id":"NCT04532151","title":"Optical Coherence Tomography Imaging in Systemic Sclerosis","phase":"NA","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"University Hospital, Strasbourg, France","has_results":false},{"nct_id":"NCT04464434","title":"Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"UMC Utrecht","has_results":false},{"nct_id":"NCT07292961","title":"Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With Scleroderma","phase":"NA","overall_status":"RECRUITING","enrollment_count":48,"lead_sponsor_name":"Hacettepe University","has_results":false},{"nct_id":"NCT06434363","title":"Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders","phase":"PHASE1, PHASE2","overall_status":"RECRUITING","enrollment_count":47,"lead_sponsor_name":"M.D. Anderson Cancer Center","has_results":false},{"nct_id":"NCT03919799","title":"KD025 in Subjects With Diffuse Cutaneous Systemic Sclerosis","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":36,"lead_sponsor_name":"Kadmon, a Sanofi Company","has_results":true},{"nct_id":"NCT05339087","title":"Efficacy and Safety of Riociguat in Incipient Pulmonary Vascular Disease as an Indicator for Early PAH","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":35,"lead_sponsor_name":"Heidelberg University","has_results":true},{"nct_id":"NCT06189495","title":"A Randomized, Double-blind, Placebo-controlled Phase II Clinical Study to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetic Profile of Genakumab Injection in Patients With Connective Tissue Disease-associated Interstitial Lung Disease","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":30,"lead_sponsor_name":"Changchun GeneScience Pharmaceutical Co., Ltd.","has_results":false},{"nct_id":"NCT04647890","title":"Effects of FT011 in Systemic Sclerosis","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Certa Therapeutics","has_results":true},{"nct_id":"NCT01559129","title":"Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effectiveness for Patients With Systemic Sclerosis With Interstitial Lung Disease","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":23,"lead_sponsor_name":"Celgene","has_results":true},{"nct_id":"NCT05859997","title":"Universal CAR-T Cells (BRL-301) in Relapse or Refractory Autoimmune Diseases","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":15,"lead_sponsor_name":"Bioray Laboratories","has_results":false},{"nct_id":"NCT06614270","title":"Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases","phase":"NA","overall_status":"RECRUITING","enrollment_count":15,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT03757065","title":"Cell Surface Marker Expression in Autoimmune Diseases","phase":"","overall_status":"COMPLETED","enrollment_count":14,"lead_sponsor_name":"Alpine Immune Sciences, Inc.","has_results":false},{"nct_id":"NCT07413341","title":"A Clinical Study of TI-0032-III Injection in Patients With Relapsed and Refractory Autoimmune Diseases","phase":"PHASE1","overall_status":"RECRUITING","enrollment_count":12,"lead_sponsor_name":"Therorna","has_results":false},{"nct_id":"NCT03630211","title":"Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis","phase":"PHASE2","overall_status":"RECRUITING","enrollment_count":8,"lead_sponsor_name":"Paul Szabolcs","has_results":false},{"nct_id":"NCT04837131","title":"A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":4,"lead_sponsor_name":"Michael M. Pham","has_results":true}],"total":32},"guidelines":[],"source":"Drug Landscape verified database"}