{"disease":{"id":"sars-severe-acute-respiratory-syndrome","name":"sars severe acute respiratory syndrome"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT04838795","title":"Sisonke (Together): OPEN LABEL TRIAL COVID-19","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":477102,"lead_sponsor_name":"Wits Health Consortium (Pty) Ltd","has_results":false},{"nct_id":"NCT05097677","title":"Follow-up of Covid-19 Long Term Sequelae","phase":"","overall_status":"COMPLETED","enrollment_count":7599,"lead_sponsor_name":"Azienda Ospedaliera Universitaria Integrata Verona","has_results":false},{"nct_id":"NCT04542915","title":"COVID-19-Related Health and Practices Among Dental Hygienists","phase":"","overall_status":"COMPLETED","enrollment_count":6976,"lead_sponsor_name":"American Dental Association","has_results":false},{"nct_id":"NCT04325646","title":"Sero-epidemiological Study of the SARS-CoV-2 Virus Responsible for COVID-19 in France","phase":"","overall_status":"COMPLETED","enrollment_count":5000,"lead_sponsor_name":"Institut Pasteur","has_results":false},{"nct_id":"NCT05543616","title":"A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children","phase":"PHASE3","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":4292,"lead_sponsor_name":"BioNTech SE","has_results":false},{"nct_id":"NCT04540185","title":"A Phase 3 Randomized Double Blind Efficacy and Safety Study of Oral Polio Vaccine and NA-831 for Covid-19","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":3600,"lead_sponsor_name":"Biomed Industries, Inc.","has_results":false},{"nct_id":"NCT04674189","title":"A Study to Evaluate the Safety and Immunogenicity of Vaccine CVnCoV in Healthy Adults in Germany for COVID-19","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":2357,"lead_sponsor_name":"CureVac","has_results":true},{"nct_id":"NCT04644159","title":"Longitudinal Follow-up of a Population Cohort in a French City With High SARS-CoV-2 Circulation, in Early 2020 [COVID-19]","phase":"","overall_status":"COMPLETED","enrollment_count":1000,"lead_sponsor_name":"Institut Pasteur","has_results":false},{"nct_id":"NCT04381819","title":"Norwegian SARS-CoV-2 Study - Virological, Clinical and Immunological Characterisation of COVID-19","phase":"","overall_status":"UNKNOWN","enrollment_count":1000,"lead_sponsor_name":"Oslo University Hospital","has_results":false},{"nct_id":"NCT04328961","title":"Hydroxychloroquine for COVID-19 Post-exposure Prophylaxis (PEP)","phase":"PHASE2, PHASE3","overall_status":"COMPLETED","enrollment_count":943,"lead_sponsor_name":"University of Washington","has_results":true},{"nct_id":"NCT04515147","title":"A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":668,"lead_sponsor_name":"CureVac","has_results":true},{"nct_id":"NCT04728802","title":"Proxalutamide Treatment for Hospitalized COVID-19 Patients","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":645,"lead_sponsor_name":"Applied Biology, Inc.","has_results":true},{"nct_id":"NCT04516811","title":"Therapeutic Use of Convalescent Plasma in the Treatment of Patients With Moderate to Severe COVID-19","phase":"PHASE3","overall_status":"UNKNOWN","enrollment_count":600,"lead_sponsor_name":"South African National Blood Service","has_results":false},{"nct_id":"NCT04546581","title":"Inpatient Treatment of COVID-19 With Anti-Coronavirus Immunoglobulin (ITAC)","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":593,"lead_sponsor_name":"University of Minnesota","has_results":true},{"nct_id":"NCT04366908","title":"Prevention and Treatment With Calcifediol of COVID-19 Induced Acute Respiratory Syndrome","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":517,"lead_sponsor_name":"Maimónides Biomedical Research Institute of Córdoba","has_results":false},{"nct_id":"NCT04558476","title":"Efficacy of CONvalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilation","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":475,"lead_sponsor_name":"University of Liege","has_results":false},{"nct_id":"NCT04476979","title":"Comparison of Tocilizumab Plus Dexamethasone vs. Dexamethasone for Patients With Covid-19","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":453,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT04649931","title":"Differences in Exhaled Breath by Using Ion Mobility Spectrometry (IMS) in Subjects Tested for SARS-CoV-2 Infection (COVID-19 Disease)","phase":"","overall_status":"COMPLETED","enrollment_count":450,"lead_sponsor_name":"B. Braun Melsungen AG","has_results":false},{"nct_id":"NCT04343729","title":"Methylprednisolone in the Treatment of Patients With Signs of Severe Acute Respiratory Syndrome in Covid-19","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":416,"lead_sponsor_name":"Fundação de Medicina Tropical Dr. Heitor Vieira Dourado","has_results":false},{"nct_id":"NCT04701710","title":"Prophylaxis Covid-19 in Healthcare Agents by Intensive Treatment With Ivermectin and Iota-carrageenan","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"Maria de los Angeles Peral de Bruno","has_results":false},{"nct_id":"NCT04629703","title":"Double-Blind, Randomized, Placebo-Controlled, Multi-Center Phase 3 Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjects","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":280,"lead_sponsor_name":"Rigel Pharmaceuticals","has_results":false},{"nct_id":"NCT04323527","title":"Chloroquine Diphosphate for the Treatment of Severe Acute Respiratory Syndrome Secondary to SARS-CoV2","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":278,"lead_sponsor_name":"Fundação de Medicina Tropical Dr. Heitor Vieira Dourado","has_results":false},{"nct_id":"NCT04446429","title":"Anti-Androgen Treatment for COVID-19","phase":"NA","overall_status":"COMPLETED","enrollment_count":268,"lead_sponsor_name":"Applied Biology, Inc.","has_results":true},{"nct_id":"NCT04784481","title":"Ivermectin Reproposing for Mild Stage COVID-19 Outpatients","phase":"PHASE1, PHASE2","overall_status":"COMPLETED","enrollment_count":254,"lead_sponsor_name":"Ministry of Public Health, Argentina","has_results":false},{"nct_id":"NCT04853199","title":"Quercetin In The Treatment Of SARS-COV 2","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Hôpital Universitaire Sahloul","has_results":false},{"nct_id":"NCT04306393","title":"Nitric Oxide Gas Inhalation in Severe Acute Respiratory Syndrome in COVID-19","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":200,"lead_sponsor_name":"Massachusetts General Hospital","has_results":true},{"nct_id":"NCT04559113","title":"Methylprednisolone in COVID-19 Patients (Methyl19LGH)","phase":"NA","overall_status":"UNKNOWN","enrollment_count":200,"lead_sponsor_name":"Lahore General Hospital","has_results":false},{"nct_id":"NCT05107258","title":"A Clinical Evaluation of Pine Trees Health Test System Including the Pine Trees Health Reader and COVID-19 Test for Point-of-Care","phase":"","overall_status":"COMPLETED","enrollment_count":195,"lead_sponsor_name":"Pine Trees, Inc.","has_results":false},{"nct_id":"NCT05074719","title":"Index Individuals in SARS-CoV-2 Prevention Research Studies (COVID-19 Index Individuals Companion Study)","phase":"","overall_status":"COMPLETED","enrollment_count":155,"lead_sponsor_name":"University of Washington","has_results":false},{"nct_id":"NCT04342650","title":"Chloroquine Diphosphate in the Prevention of SARS in Covid-19 Infection","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":152,"lead_sponsor_name":"Fundação de Medicina Tropical Dr. Heitor Vieira Dourado","has_results":false},{"nct_id":"NCT05947812","title":"A Clinical Evaluation of the Safety and Efficacy of Randomized Placebo Versus the 8-aminoquinoline Tafenoquine for Early Symptom Resolution in Patients With Mild to Moderate COVID 19 Disease and Low Risk of Disease Progression","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":148,"lead_sponsor_name":"60P Australia Pty Ltd","has_results":false},{"nct_id":"NCT04860258","title":"COVID-19: A Study to Evaluate Safety, Reactogenicity and Immunogenicity of the SARS-CoV-2 mRNA Vaccine CVnCoV in Adults With Co-morbidities","phase":"PHASE3","overall_status":"TERMINATED","enrollment_count":129,"lead_sponsor_name":"CureVac","has_results":true},{"nct_id":"NCT04497454","title":"Mechanical Ventilation Strategy for Coronavirus Disease 2019 (COVID-19)","phase":"NA","overall_status":"UNKNOWN","enrollment_count":128,"lead_sponsor_name":"University of Sao Paulo General Hospital","has_results":false},{"nct_id":"NCT04720794","title":"A Study To Evaluate The Performance of the Lucira Health All-In-One COVID-19 Test Kit vs Hologic Panther Fusion","phase":"NA","overall_status":"COMPLETED","enrollment_count":101,"lead_sponsor_name":"Lucira Health Inc","has_results":false},{"nct_id":"NCT04374734","title":"Quantification of Radiological Pulmonary Involvement in Acute Respiratory Failure","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"University Hospital, Strasbourg, France","has_results":false},{"nct_id":"NCT04659486","title":"Adolescents With COVID-19/MIS-C at HCFMUSP","phase":"NA","overall_status":"UNKNOWN","enrollment_count":100,"lead_sponsor_name":"University of Sao Paulo","has_results":false},{"nct_id":"NCT04480580","title":"Seroprevalence of SARS-Cov-2 in the Setting of a Non-dedicated COVID-19 Hospital in a Low CoV-2 Incidence Area: Implications for Surgery","phase":"","overall_status":"COMPLETED","enrollment_count":100,"lead_sponsor_name":"University of Cagliari","has_results":false},{"nct_id":"NCT04822818","title":"EFFICACY and SAFETY OF BEVACIZUMAB (ZIRABEV®) IN PATIENTS WITH SEVERE HYPOXEMIC COVID-19","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":96,"lead_sponsor_name":"Assistance Publique - Hôpitaux de Paris","has_results":false},{"nct_id":"NCT04443673","title":"Glycine Supplement for Severe COVID-19","phase":"NA","overall_status":"TERMINATED","enrollment_count":59,"lead_sponsor_name":"Instituto Nacional de Enfermedades Respiratorias","has_results":false},{"nct_id":"NCT04409873","title":"Antiseptic Mouthwash / Pre-Procedural Rinse on SARS-CoV-2 Load (COVID-19)","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":54,"lead_sponsor_name":"University of California, San Francisco","has_results":true},{"nct_id":"NCT04517630","title":"Renal Biomarkers in AKI and COVID-19","phase":"","overall_status":"COMPLETED","enrollment_count":51,"lead_sponsor_name":"Instituto Nacional de Enfermedades Respiratorias","has_results":false},{"nct_id":"NCT04978025","title":"Colloidal Silver, Treatment of COVID-19","phase":"NA","overall_status":"UNKNOWN","enrollment_count":50,"lead_sponsor_name":"Hôpital Universitaire Sahloul","has_results":false},{"nct_id":"NCT04615052","title":"Home-based Exercise in COVID-19 Survivors","phase":"NA","overall_status":"UNKNOWN","enrollment_count":50,"lead_sponsor_name":"University of Sao Paulo","has_results":false},{"nct_id":"NCT04584658","title":"Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection (DYADS Study)","phase":"","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"Cambridge University Hospitals NHS Foundation Trust","has_results":false},{"nct_id":"NCT04480333","title":"Safety, Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-831","phase":"PHASE1","overall_status":"UNKNOWN","enrollment_count":45,"lead_sponsor_name":"Biomed Industries, Inc.","has_results":false},{"nct_id":"NCT04327505","title":"Safety and Efficacy of Hyperbaric Oxygen for ARDS in Patients With COVID-19","phase":"PHASE2, PHASE3","overall_status":"TERMINATED","enrollment_count":34,"lead_sponsor_name":"Karolinska Institutet","has_results":false},{"nct_id":"NCT04560257","title":"High Flow Nasal Cannula HFNC In Covid-19 Patients","phase":"NA","overall_status":"UNKNOWN","enrollment_count":30,"lead_sponsor_name":"Lahore General Hospital","has_results":false},{"nct_id":"NCT04335786","title":"Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection Disease","phase":"PHASE4","overall_status":"TERMINATED","enrollment_count":23,"lead_sponsor_name":"Radboud University Medical Center","has_results":false},{"nct_id":"NCT04382391","title":"Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms","phase":"NA","overall_status":"TERMINATED","enrollment_count":21,"lead_sponsor_name":"Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)","has_results":true},{"nct_id":"NCT04320511","title":"Beaumont Quantitative Lung Function Imaging to Characterize Patients With SARS-COV 2","phase":"","overall_status":"TERMINATED","enrollment_count":15,"lead_sponsor_name":"Corewell Health East","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}