{"disease":{"id":"rhytides","name":"rhytides"},"drugs":{"marketed":[],"pipeline":[],"offLabel":[],"totalMarketed":0,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT01189760","title":"Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines and Frown Lines","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":917,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT02261493","title":"A Safety and Efficacy Study of OnabotulinumtoxinA in Upper Facial Rhytides","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":787,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT01189747","title":"Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":446,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT02261467","title":"A Safety and Efficacy Study of OnabotulinumtoxinA in Forehead and Glabellar Facial Rhytides","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":421,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT01797081","title":"BOTOX® in the Treatment of Crow's Feet Lines in Japan","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":300,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT06657365","title":"Safety and Efficacy Evaluation of the Monopolar Radiofrequency Device for the Improvement of Facial Wrinkles","phase":"NA","overall_status":"COMPLETED","enrollment_count":284,"lead_sponsor_name":"CLASSYS Inc.","has_results":false},{"nct_id":"NCT01814670","title":"Treatment With Botulinum Toxin Type A (BOTOX®) in Chinese Patients With Moderate to Severe Frown Lines","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":185,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT06724510","title":"Safety and Efficacy Evaluation of High Intensity Focused Ultrasound Device in Eyebrow Lifting","phase":"NA","overall_status":"RECRUITING","enrollment_count":180,"lead_sponsor_name":"CLASSYS Inc.","has_results":false},{"nct_id":"NCT01391299","title":"Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Forehead and Frown Lines","phase":"NA","overall_status":"COMPLETED","enrollment_count":175,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT01777620","title":"A Study of Subject Satisfaction With BOTOX® Cosmetic Treatment in Facial Rhytides","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":125,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT02176356","title":"Patient Satisfaction Study of Combined Facial Treatment With BOTOX® Cosmetic, JUVÉDERM® and LATISSE® (HARMONY Study)","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":116,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT01608659","title":"An Observational Retrospective Study to Evaluate Treatment Patterns of Botulinum Toxin Type A","phase":"","overall_status":"COMPLETED","enrollment_count":110,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT07160777","title":"Performance and Safety of Semical Dermal Fillers in Facial Rejuvenation","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":80,"lead_sponsor_name":"Semikal Technology","has_results":false},{"nct_id":"NCT04609020","title":"Study to Evaluate Subject Satisfaction With Facial Appearance and Impact of Combined Facial Treatment","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":64,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT06104514","title":"Safety and Efficacy of SofWave Treatment to Lift the Upper Lip and Improve the Peri-Oral Rhytids","phase":"NA","overall_status":"COMPLETED","enrollment_count":60,"lead_sponsor_name":"Sofwave Medical LTD","has_results":false},{"nct_id":"NCT03712449","title":"A Study to Evaluate Participant Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":59,"lead_sponsor_name":"Allergan","has_results":true},{"nct_id":"NCT04185909","title":"Renuvion Dermal System for Dermal Resurfacing","phase":"NA","overall_status":"COMPLETED","enrollment_count":55,"lead_sponsor_name":"Apyx Medical","has_results":true},{"nct_id":"NCT03286283","title":"The Use of J-Plasma® for Dermal Resurfacing","phase":"NA","overall_status":"COMPLETED","enrollment_count":55,"lead_sponsor_name":"Apyx Medical","has_results":true},{"nct_id":"NCT07079501","title":"Eye Cream 8-Week Efficacy Clinical Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":50,"lead_sponsor_name":"ChinaNorm","has_results":false},{"nct_id":"NCT07067086","title":"Cream Short-term Efficacy Clinical Study","phase":"NA","overall_status":"COMPLETED","enrollment_count":42,"lead_sponsor_name":"ChinaNorm","has_results":false},{"nct_id":"NCT05041465","title":"The Cosmetic Effect of Mineral Clay Masks","phase":"NA","overall_status":"COMPLETED","enrollment_count":41,"lead_sponsor_name":"University of California, Davis","has_results":false},{"nct_id":"NCT02954315","title":"The Effect of Almonds on Skin Lipids and Wrinkles","phase":"NA","overall_status":"COMPLETED","enrollment_count":31,"lead_sponsor_name":"University of California, Davis","has_results":false},{"nct_id":"NCT07526870","title":"Intradermal Microbotulinum Toxin for Sebum Reduction and Facial Pore Improvement","phase":"NA","overall_status":"COMPLETED","enrollment_count":30,"lead_sponsor_name":"Instituto de Oftalmología Fundación Conde de Valenciana","has_results":false},{"nct_id":"NCT03776461","title":"Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles","phase":"NA","overall_status":"COMPLETED","enrollment_count":25,"lead_sponsor_name":"Venus Concept","has_results":true},{"nct_id":"NCT04162496","title":"Restylane Refyne for Correction of Horizontal Neck Rhytides","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":24,"lead_sponsor_name":"Siperstein Dermatology","has_results":false},{"nct_id":"NCT07523373","title":"Facial Nerve Monitoring During Parotid and Facial Surgery Using a Non-Invasive Patch","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":20,"lead_sponsor_name":"Sheba Medical Center","has_results":false},{"nct_id":"NCT07155278","title":"Efficacy & Safety of hADM Skin Booster","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":20,"lead_sponsor_name":"Yonsei University","has_results":false},{"nct_id":"NCT07072806","title":"A Study Comparing the Safety, Efficacy, and Diffusion of Letibotulinum Toxin A Versus Other Botulinum Toxin Products in Adults With Moderate-to-Severe Forehead Wrinkles","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":20,"lead_sponsor_name":"Yonsei University","has_results":false},{"nct_id":"NCT04586816","title":"Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging","phase":"NA","overall_status":"COMPLETED","enrollment_count":19,"lead_sponsor_name":"Integrative Skin Science and Research","has_results":false},{"nct_id":"NCT05514834","title":"BCT-HA Kit for Dehydrated and Wrinkled Skin","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"University of Minnesota","has_results":false},{"nct_id":"NCT03831477","title":"Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles","phase":"NA","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"Venus Concept","has_results":true},{"nct_id":"NCT05517538","title":"Split-face Study: Cosmetic Botulinum Toxin Type A Injection Under Electromyography-guidance Versus Conventional Palpation Technique","phase":"NA","overall_status":"COMPLETED","enrollment_count":15,"lead_sponsor_name":"Mohamed Hayder Oleish Salih","has_results":false},{"nct_id":"NCT03799484","title":"Botulinum Toxin Type A Injection After Topical Anesthesia Versus Petrolatum Ointment","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":14,"lead_sponsor_name":"The University of Texas Health Science Center, Houston","has_results":true},{"nct_id":"NCT05807412","title":"Spread of PrabotulinumtoxinA-xvfs Versus OnabotulinumtoxinA in the Treatment of Forehead Rhytides","phase":"EARLY_PHASE1","overall_status":"COMPLETED","enrollment_count":10,"lead_sponsor_name":"Lupo Center for Aesthetic and General Dermatology","has_results":false},{"nct_id":"NCT06421207","title":"Open Label Study Exploring Tissue Histopathology After Ellacor® Procedure in an Abdominoplasty Model.","phase":"NA","overall_status":"COMPLETED","enrollment_count":6,"lead_sponsor_name":"Cytrellis Biosystems, Inc.","has_results":false},{"nct_id":"NCT06502470","title":"Healing Study of Fractional Skin Resurfacing and Tissue Histopathology After Ellacor Treatment","phase":"NA","overall_status":"COMPLETED","enrollment_count":3,"lead_sponsor_name":"Cytrellis Biosystems, Inc.","has_results":false},{"nct_id":"NCT04994990","title":"Effective OnabotulinumtoxinA Dose Response Study for Upper Facial Wrinkles","phase":"NA","overall_status":"WITHDRAWN","enrollment_count":0,"lead_sponsor_name":"Northwell Health","has_results":false}],"total":37},"guidelines":[],"source":"Drug Landscape verified database"}