{"disease":{"id":"rheumatic","name":"rheumatic"},"drugs":{"marketed":[{"drug_id":"prednisone","indication_name":"Acute rheumatic carditis","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Deltasone","generic_name":"prednisone","company_name":"Generic (originally Schering)","drug_phase":"marketed","molecular_target":"Annexin A1, Sodium/nucleoside cotransporter 1, Glucocorticoid receptor","drug_class":"Corticosteroid [EPC]","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"dexamethasone-phosphate","indication_name":"Acute rheumatic carditis","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Dexamethasone Sodium Phosphate","generic_name":"dexamethasone phosphate","company_name":"Merck & Co.","drug_phase":"marketed","molecular_target":"Androgen receptor, Glucocorticoid receptor, Mineralocorticoid receptor","drug_class":"Corticosteroid","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"sodium-succinate","indication_name":"Rheumatic Disorders","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"SODIUM SUCCINATE","company_name":"","drug_phase":"marketed","molecular_target":"","drug_class":"","quality_score":30,"revenue":null,"mechanism":""},{"drug_id":"sarilumab","indication_name":"Polymyalgia Rheumatica","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"SARILUMAB","company_name":"","drug_phase":"marketed","molecular_target":"IL-6 receptors (sIL-6R and mIL-6R)","drug_class":"Interleukin-6 Receptor Antagonist [EPC]","quality_score":60,"revenue":null,"mechanism":"Sarilumab inhibits IL-6 signaling by binding to both soluble and membrane-bound IL-6 receptors."},{"drug_id":"hydrocortisone-succinate","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Solu-Cortef","generic_name":"hydrocortisone succinate","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"Glucocorticoid receptor","drug_class":"Corticosteroid","quality_score":42,"revenue":null,"mechanism":""},{"drug_id":"benzylpenicillin","indication_name":"Rheumatic Fever Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Penicillin G Potassium In Plastic Container","generic_name":"Benzylpenicillin","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"","drug_class":"Penicillin-class Antibacterial","quality_score":32,"revenue":null,"mechanism":""},{"drug_id":"hydrocortisone-acetate","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Cortifoam","generic_name":"HYDROCORTISONE ACETATE","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"Corticosteroid-binding globulin","drug_class":"Corticosteroid","quality_score":42,"revenue":null,"mechanism":""},{"drug_id":"cortisone-acetate","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Cortone","generic_name":"CORTISONE ACETATE","company_name":"","drug_phase":"marketed","molecular_target":"Corticosteroid-binding globulin","drug_class":"alpha-Adrenergic Agonist [EPC]","quality_score":29,"revenue":null,"mechanism":""},{"drug_id":"sulfadiazine","indication_name":"Rheumatic Fever Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Sulfadiazine","generic_name":"SULFADIAZINE","company_name":"Eli Lilly","drug_phase":"marketed","molecular_target":"5-hydroxytryptamine receptor 2A","drug_class":"Sulfonamide Antibacterial [EPC]","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"betamethasone-acetate","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Celestone Soluspan","generic_name":"BETAMETHASONE ACETATE","company_name":"","drug_phase":"marketed","molecular_target":"Glucocorticoid receptor","drug_class":"Corticosteroid","quality_score":42,"revenue":null,"mechanism":""},{"drug_id":"dexamethasone","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Decadron","generic_name":"dexamethasone","company_name":"Generic (originally Merck)","drug_phase":"marketed","molecular_target":"Annexin A1, Interleukin-4, Androgen receptor","drug_class":"Corticosteroid [EPC]","quality_score":44,"revenue":null,"mechanism":""},{"drug_id":"erythromycin","indication_name":"Rheumatic Fever Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"E-Mycin","generic_name":"erythromycin","company_name":"Generic (originally Abbott/Lilly)","drug_phase":"marketed","molecular_target":"Aldehyde oxidase, Bile salt export pump, Cytochrome P450 1B1","drug_class":"Macrolide [EPC]","quality_score":27,"revenue":null,"mechanism":""},{"drug_id":"prednison","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"prednison","company_name":"Wen Zhang","drug_phase":"marketed","molecular_target":"Annexin A1, Sodium/nucleoside cotransporter 1, Glucocorticoid receptor","drug_class":"","quality_score":19,"revenue":null,"mechanism":null},{"drug_id":"methylprednisolone","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Medrol","generic_name":"methylprednisolone","company_name":"Generic (originally Upjohn/Pfizer)","drug_phase":"marketed","molecular_target":"Annexin A1, Short transient receptor potential channel 5, Glucocorticoid receptor","drug_class":"Glucocorticoid (corticosteroid)","quality_score":62,"revenue":null,"mechanism":"Potent synthetic glucocorticoid with 5x hydrocortisone potency and minimal mineralocorticoid activity, used for severe inflammatory conditions."},{"drug_id":"hydrocortisone","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Cortef","generic_name":"hydrocortisone","company_name":"Generic (originally Merck/Upjohn)","drug_phase":"marketed","molecular_target":"Annexin A1, Corticosteroid-binding globulin, Nitric oxide synthase, inducible","drug_class":"Corticosteroid [EPC]","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"triamcinolone","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Rodinolone","generic_name":"TRIAMCINOLONE","company_name":"","drug_phase":"marketed","molecular_target":"Glucocorticoid receptor","drug_class":"Corticosteroid","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"prednisone","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Deltasone","generic_name":"prednisone","company_name":"Generic (originally Schering)","drug_phase":"marketed","molecular_target":"Annexin A1, Sodium/nucleoside cotransporter 1, Glucocorticoid receptor","drug_class":"Corticosteroid [EPC]","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"erythrocin","indication_name":"Rheumatic Fever Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Benzamycin","generic_name":"Erythromycin Lactobionate","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"Potassium voltage-gated channel subfamily H member 2","drug_class":"Macrolide","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"intra-articular-corticosteroid-injections","indication_name":"Polymyalgia rheumatica","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Intra-articular corticosteroid injections","generic_name":"intra-articular-corticosteroid-injections","company_name":"Pfizer","drug_phase":"marketed","molecular_target":"Glucocorticoid receptor","drug_class":"Corticosteroid","quality_score":10,"revenue":null,"mechanism":""},{"drug_id":"betamethasone","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Betametasone","generic_name":"BETAMETHASONE","company_name":"","drug_phase":"marketed","molecular_target":"Glucocorticoid receptor","drug_class":"Corticosteroid","quality_score":65,"revenue":null,"mechanism":"Betamethasone works by binding to the glucocorticoid receptor, which then triggers a series of downstream effects that reduce inflammation and suppress the immune system."},{"drug_id":"cortisol","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Cortisol","company_name":"University of Zurich","drug_phase":"marketed","molecular_target":"Annexin A1, Corticosteroid-binding globulin, Nitric oxide synthase, inducible","drug_class":"","quality_score":null,"revenue":null,"mechanism":null},{"drug_id":"prednisolone","indication_name":"Polymyalgia rheumatica","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Prelone","generic_name":"prednisolone","company_name":"Generic (originally Schering)","drug_phase":"marketed","molecular_target":"Annexin A1, Corticosteroid-binding globulin, G-protein coupled bile acid receptor 1","drug_class":"Glucocorticoid (corticosteroid)","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"prednisolone","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":"Prelone","generic_name":"prednisolone","company_name":"Generic (originally Schering)","drug_phase":"marketed","molecular_target":"Annexin A1, Corticosteroid-binding globulin, G-protein coupled bile acid receptor 1","drug_class":"Glucocorticoid (corticosteroid)","quality_score":40,"revenue":null,"mechanism":""},{"drug_id":"penicillin","indication_name":"Rheumatic Fever Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"penicillin","company_name":"Karlstad University","drug_phase":"marketed","molecular_target":"Bacterial penicillin-binding protein, Beta-lactamase, Beta-lactamase TEM","drug_class":"","quality_score":null,"revenue":null,"mechanism":null},{"drug_id":"prednisolon","indication_name":"Polymyalgia rheumatica","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"prednisolon","company_name":"Hannover Medical School","drug_phase":"marketed","molecular_target":"Annexin A1, Corticosteroid-binding globulin, G-protein coupled bile acid receptor 1","drug_class":"","quality_score":null,"revenue":null,"mechanism":null},{"drug_id":"prednisolon","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"prednisolon","company_name":"Hannover Medical School","drug_phase":"marketed","molecular_target":"Annexin A1, Corticosteroid-binding globulin, G-protein coupled bile acid receptor 1","drug_class":"","quality_score":null,"revenue":null,"mechanism":null},{"drug_id":"methylprednisolon","indication_name":"Rheumatic heart disease","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Methylprednisolon","company_name":"Leiden University Medical Center","drug_phase":"marketed","molecular_target":"Annexin A1, Short transient receptor potential channel 5, Glucocorticoid receptor","drug_class":"","quality_score":null,"revenue":null,"mechanism":null},{"drug_id":"phenoxymethylpenicillin","indication_name":"Rheumatic Fever Prevention","indication_type":"approved","phase":null,"line_of_therapy":null,"is_primary_indication":false,"pivotal_trial_result":null,"pivotal_trial_p_value":null,"patient_population":null,"brand_name":null,"generic_name":"Phenoxymethylpenicillin","company_name":"Katarina Hedin","drug_phase":"marketed","molecular_target":"Bacterial penicillin-binding protein, Penicillin-binding protein 1A","drug_class":"","quality_score":null,"revenue":null,"mechanism":null}],"pipeline":[],"offLabel":[],"totalMarketed":28,"totalPipeline":0},"trials":{"data":[{"nct_id":"NCT06568029","title":"Construct Validity and Responsiveness of EQ-5D-3L in Patients With Rheumatic Disease","phase":"","overall_status":"COMPLETED","enrollment_count":77651,"lead_sponsor_name":"Karolinska Institutet","has_results":false},{"nct_id":"NCT05276999","title":"Rheumatic Heart Disease Community Streptococcal Treatment Program \"RESET\"","phase":"NA","overall_status":"COMPLETED","enrollment_count":66123,"lead_sponsor_name":"Children's Hospital Medical Center, Cincinnati","has_results":false},{"nct_id":"NCT04239521","title":"The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata","phase":"","overall_status":"COMPLETED","enrollment_count":51955,"lead_sponsor_name":"Momentum Data","has_results":false},{"nct_id":"NCT03840928","title":"PatientSpot Formerly Known as ArthritisPower","phase":"","overall_status":"UNKNOWN","enrollment_count":40000,"lead_sponsor_name":"Global Healthy Living Foundation","has_results":false},{"nct_id":"NCT02111564","title":"A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":12024,"lead_sponsor_name":"Janssen Research & Development, LLC","has_results":true},{"nct_id":"NCT04806620","title":"Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research","phase":"","overall_status":"RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Brain Inflammation Collaborative","has_results":false},{"nct_id":"NCT06766552","title":"A Registry Study Assessing PRO, Dosing Patterns, and Safety of Vunakizumab in Patients With General Rheumatic Diseases.","phase":"","overall_status":"NOT_YET_RECRUITING","enrollment_count":10000,"lead_sponsor_name":"Second Affiliated Hospital, School of Medicine, Zhejiang University","has_results":false},{"nct_id":"NCT04936815","title":"Echocardiographic Screening of Pregnant Women During Antenatal Care","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":9000,"lead_sponsor_name":"Thomas Pilgrim","has_results":false},{"nct_id":"NCT00024479","title":"Studies of the Natural History of Rheumatic Diseases","phase":"","overall_status":"RECRUITING","enrollment_count":7500,"lead_sponsor_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)","has_results":false},{"nct_id":"NCT02694185","title":"Secondary Event Prevention Using Population Risk Management After PCI and for Anti-Rheumatic Medications","phase":"NA","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":5269,"lead_sponsor_name":"VA Office of Research and Development","has_results":true},{"nct_id":"NCT05991219","title":"Screening and Secondary Prevention Rheumatic Heart Disease Study","phase":"","overall_status":"RECRUITING","enrollment_count":5000,"lead_sponsor_name":"National Institute of Cardiovascular Diseases, Pakistan","has_results":false},{"nct_id":"NCT04402086","title":"Rheumatology Patient Registry and Biorepository","phase":"","overall_status":"RECRUITING","enrollment_count":5000,"lead_sponsor_name":"Yale University","has_results":false},{"nct_id":"NCT06932497","title":"Gemelli Longitudinal Cohort on Long-term Outcomes in RheumatIc diseAses","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":5000,"lead_sponsor_name":"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","has_results":false},{"nct_id":"NCT02832544","title":"INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Non-Inferiority","phase":"PHASE3","overall_status":"COMPLETED","enrollment_count":4565,"lead_sponsor_name":"Population Health Research Institute","has_results":false},{"nct_id":"NCT04102930","title":"Clinical and Immunogenetic Characterization of Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR)","phase":"","overall_status":"RECRUITING","enrollment_count":4500,"lead_sponsor_name":"University of Leeds","has_results":false},{"nct_id":"NCT04780607","title":"Outcomes of Mitral Valve Surgery in Patients Affected by Rheumatic Heart Disease","phase":"","overall_status":"UNKNOWN","enrollment_count":4000,"lead_sponsor_name":"Beijing Anzhen Hospital","has_results":false},{"nct_id":"NCT05935709","title":"DANIsh VASculitis Database (DANIVAS)","phase":"","overall_status":"RECRUITING","enrollment_count":3000,"lead_sponsor_name":"Aarhus University Hospital","has_results":false},{"nct_id":"NCT04845997","title":"COVID-19 Vaccination in Patients With Rheumatic Diseases","phase":"","overall_status":"UNKNOWN","enrollment_count":3000,"lead_sponsor_name":"Sociedad Argentina de Reumatologia","has_results":false},{"nct_id":"NCT04568421","title":"Argentinian Registry of Patients With Rheumatic Diseases and COVID-19 Infection","phase":"","overall_status":"COMPLETED","enrollment_count":2982,"lead_sponsor_name":"Sociedad Argentina de Reumatologia","has_results":false},{"nct_id":"NCT05250154","title":"Rheumatic Heart Disease Research and Screening in Nepal: A Feasibility Study","phase":"","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":2438,"lead_sponsor_name":"University of Washington","has_results":false},{"nct_id":"NCT03558971","title":"Patient Self-administration of Cortisol for Cortisol-responding Disorders in Men and Women Over the Age of 17","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":2430,"lead_sponsor_name":"Helen Foundation","has_results":false},{"nct_id":"NCT07512401","title":"Methotrexate Monitoring Target Trial Emulation","phase":"","overall_status":"COMPLETED","enrollment_count":2414,"lead_sponsor_name":"Mayo Clinic","has_results":false},{"nct_id":"NCT07065474","title":"Effectiveness of Edutainment-Based Interventions in Increasing Knowledge of Rheumatic Fever and Rheumatic Heart Disease Among School-Going Children in Nepal: Study Protocol for Colors to Save Hearts Quasi-Experimental Pretest-Posttest Study","phase":"NA","overall_status":"NOT_YET_RECRUITING","enrollment_count":2400,"lead_sponsor_name":"Kathmandu Institute of Child Health","has_results":false},{"nct_id":"NCT05504928","title":"Effectiveness of a School-centered Prevention Program on Prevalence of Latent Rheumatic Heart Disease","phase":"NA","overall_status":"RECRUITING","enrollment_count":2300,"lead_sponsor_name":"Insel Gruppe AG, University Hospital Bern","has_results":false},{"nct_id":"NCT04754698","title":"COVID-19 CoronaVac in Patients With Autoimmune Rheumatic Diseases and HIV/AIDS","phase":"PHASE4","overall_status":"COMPLETED","enrollment_count":2196,"lead_sponsor_name":"University of Sao Paulo General Hospital","has_results":false},{"nct_id":"NCT05895487","title":"Study on Efficacy, Safety and Durability of the UniLine Prosthesis in the Treatment of Aortic and Mitral Valve Disease","phase":"","overall_status":"RECRUITING","enrollment_count":2000,"lead_sponsor_name":"Closed Joint-Stock Company NeoCor","has_results":false},{"nct_id":"NCT05668611","title":"Train the Trainer Curriculum to Scale up AI Supported Echo for RHD Screening in a Public Health System","phase":"NA","overall_status":"COMPLETED","enrollment_count":1628,"lead_sponsor_name":"Children's Hospital Medical Center, Cincinnati","has_results":false},{"nct_id":"NCT06004349","title":"Autoimmune and Autoinflammatory Genetics Study","phase":"","overall_status":"RECRUITING","enrollment_count":1500,"lead_sponsor_name":"NYU Langone Health","has_results":false},{"nct_id":"NCT05211024","title":"A Long-term Follow up Study for Patients Who Participated in the GOAL Trial (GOAL-Post)","phase":"","overall_status":"COMPLETED","enrollment_count":1423,"lead_sponsor_name":"Children's Hospital Medical Center, Cincinnati","has_results":false},{"nct_id":"NCT04542031","title":"COVID-19 in a Single Large UK Rheumatology Centre and Impact on QOL","phase":"NA","overall_status":"COMPLETED","enrollment_count":1010,"lead_sponsor_name":"The Royal Wolverhampton Hospitals NHS Trust","has_results":false},{"nct_id":"NCT05443321","title":"Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes","phase":"NA","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":1006,"lead_sponsor_name":"Brigham and Women's Hospital","has_results":false},{"nct_id":"NCT05693545","title":"GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial","phase":"PHASE2","overall_status":"ACTIVE_NOT_RECRUITING","enrollment_count":1004,"lead_sponsor_name":"Children's Hospital Medical Center, Cincinnati","has_results":false},{"nct_id":"NCT06940869","title":"Network to Understand Reproductive Rheumatology Registry","phase":"","overall_status":"ENROLLING_BY_INVITATION","enrollment_count":1000,"lead_sponsor_name":"Duke University","has_results":false},{"nct_id":"NCT03346525","title":"Determining the Impact of Penicillin in Latent RHD: The GOAL Trial","phase":"PHASE2","overall_status":"UNKNOWN","enrollment_count":807,"lead_sponsor_name":"Children's National Research Institute","has_results":false},{"nct_id":"NCT06499233","title":"Efficacy and Safety of Prophylactic Treatment for Pneumocystis Jirovecii Pneumonia in Patients With Autoimmune Inflammatory Rheumatic Disease","phase":"PHASE4","overall_status":"RECRUITING","enrollment_count":800,"lead_sponsor_name":"Tongji Hospital","has_results":false},{"nct_id":"NCT06965322","title":"Study on the Detection of Pleuropulmonary Manifestations in Rheumatoid Arthritis","phase":"","overall_status":"RECRUITING","enrollment_count":800,"lead_sponsor_name":"Medical University Innsbruck","has_results":false},{"nct_id":"NCT06011512","title":"Risk of Diabetes Mellitus in Patients With Giant Cell Arthritis and Polymyalgia Rheumatica.","phase":"","overall_status":"RECRUITING","enrollment_count":800,"lead_sponsor_name":"Salome Kristensen","has_results":false},{"nct_id":"NCT04848493","title":"National Project on Vaccines, COVID-19 and Frail Patients","phase":"","overall_status":"COMPLETED","enrollment_count":747,"lead_sponsor_name":"Azienda USL Reggio Emilia - IRCCS","has_results":false},{"nct_id":"NCT02124109","title":"The Genetic Basis of Acquired Heart Disease in Africa","phase":"","overall_status":"COMPLETED","enrollment_count":736,"lead_sponsor_name":"National Human Genome Research Institute (NHGRI)","has_results":false},{"nct_id":"NCT04704544","title":"Effectiveness of Tele-rheumatology for Delivering High Quality Rheumatology Care During the COVID-19 Crisis (EVOLVE)","phase":"NA","overall_status":"COMPLETED","enrollment_count":652,"lead_sponsor_name":"University of Alabama at Birmingham","has_results":false},{"nct_id":"NCT03454438","title":"Strategies to Improve Appropriate Referral to Rheumatologists","phase":"NA","overall_status":"COMPLETED","enrollment_count":544,"lead_sponsor_name":"Maasstad Hospital","has_results":false},{"nct_id":"NCT04426279","title":"Morbimortality of Covid-19 in Patients With Chronic Inflammatory Rheumatism Treated With Immunosuppressants","phase":"","overall_status":"TERMINATED","enrollment_count":539,"lead_sponsor_name":"University Hospital, Lille","has_results":false},{"nct_id":"NCT04398381","title":"Prognosis of SRD Patients in the ICU","phase":"","overall_status":"COMPLETED","enrollment_count":525,"lead_sponsor_name":"University Hospital, Montpellier","has_results":false},{"nct_id":"NCT05618782","title":"Clinical Trial to Evaluate the Efficacy and Safety of LEVI-04 in Patients With Osteoarthritis of the Knee","phase":"PHASE2","overall_status":"COMPLETED","enrollment_count":518,"lead_sponsor_name":"Levicept","has_results":true},{"nct_id":"NCT05807256","title":"Medically Assisted Fertilization Techniques in Systemic Immunoreumatologic Diseases","phase":"","overall_status":"RECRUITING","enrollment_count":500,"lead_sponsor_name":"IRCCS San Raffaele","has_results":false},{"nct_id":"NCT05191368","title":"Safety and Immunogenicity of Sars-cov-2 Vaccine in Patients With Rheumatic Diseases","phase":"","overall_status":"UNKNOWN","enrollment_count":500,"lead_sponsor_name":"Yunnan University of Chinese Medicine","has_results":false},{"nct_id":"NCT05516758","title":"A Study of Peresolimab (LY3462817) in Participants With Moderately-to-Severely Active Rheumatoid Arthritis","phase":"PHASE2","overall_status":"TERMINATED","enrollment_count":491,"lead_sponsor_name":"Eli Lilly and Company","has_results":true},{"nct_id":"NCT04587362","title":"The Diagnostic Ultrasound Enthesitis Tool (DUET) Study","phase":"","overall_status":"COMPLETED","enrollment_count":419,"lead_sponsor_name":"Women's College Hospital","has_results":false},{"nct_id":"NCT06806592","title":"A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases","phase":"PHASE3","overall_status":"RECRUITING","enrollment_count":400,"lead_sponsor_name":"Boehringer Ingelheim","has_results":false},{"nct_id":"NCT05291130","title":"AESCULAP® Plasmafit® Cementless Acetabular System With Vitelene® Vitamin E Stabilized Highly Crosslinked Polyethylene","phase":"","overall_status":"COMPLETED","enrollment_count":400,"lead_sponsor_name":"Federal State Budgetary Organization, Federal Center for Traumatology, Orthopedics and Arthroplasty","has_results":false}],"total":50},"guidelines":[],"source":"Drug Landscape verified database"}